Intraperitoneal kisspeptin‐10 administration ameliorates sodium arsenite‐induced reproductive toxicity in adult male mice

Andrologia ◽  
2021 ◽  
Author(s):  
Iffat Fatima ◽  
Irfan Zia Qureshi
Keyword(s):  
Adult Male ◽  
Sodium Arsenite ◽  
Reproductive Toxicity ◽  
Male Mice

Evidence for diazinon-mediated inhibition of cis-permethrin metabolism and its effects on reproductive toxicity in adult male mice

2012 ◽  
Vol 34 (4) ◽  
pp. 489-497 ◽  
Author(s):  
Dong Wang ◽  
Michihiro Kamijima ◽  
Ai Okamura ◽  
Yuki Ito ◽  
Yukie Yanagiba ◽  
...  
Keyword(s):  
Adult Male ◽  
Reproductive Toxicity ◽  
Male Mice

Growth hormone deficiency and excess alter the gut microbiome in adult male mice

2020 ◽  
Author(s):  
Jensen EA ◽  
Young JA ◽  
Jackson Z ◽  
Busken J ◽  
List EO ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Growth Hormone Deficiency ◽  
Adult Male ◽  
Gut Microbiome ◽  
Hormone Deficiency ◽  
Male Mice

Effect of Hematopoietic Stem Cells and Platelet-Rich Plasma on the Healing of Experimental Skin Burned Tissues: A Comparative Study in Adult Male Mice

2019 ◽  
Vol 42 (3) ◽  
pp. 740-754
Author(s):  
Heba Saad Eldien ◽  
Nashwa Mostafa ◽  
Ola Abd ElTawab ◽  
Hussein Hassan ◽  
Tarek Abd Elhamid ◽  
...  
Keyword(s):  
Stem Cells ◽  
Comparative Study ◽  
Hematopoietic Stem Cells ◽  
Adult Male ◽  
Platelet Rich Plasma ◽  
Male Mice ◽  
Hematopoietic Stem

The possible protective role of curcumin on the toxic effect of nicotine in the lung of adult male mice

2012 ◽  
Vol 35 (4) ◽  
pp. 805-811
Author(s):  
Dorria A.M. Zaghloul ◽  
Esam Salah Kamel ◽  
Hekmat O. Abd el-Aziz ◽  
Mohammed A. Mahmoud
Keyword(s):  
Toxic Effect ◽  
Adult Male ◽  
Protective Role ◽  
Male Mice

scholarly journals Diisopropylfluorophosphate-induced status epilepticus drives complex glial cell phenotypes in adult male mice

2021 ◽  
Vol 152 ◽  
pp. 105276
Author(s):  
Clémence Maupu ◽  
Julie Enderlin ◽  
Alexandre Igert ◽  
Myriam Oger ◽  
Stéphane Auvin ◽  
...  
Keyword(s):  
Status Epilepticus ◽  
Glial Cell ◽  
Adult Male ◽  
Male Mice ◽  
Cell Phenotypes

Male reproductive toxicity of sodium arsenite in mice

2004 ◽  
Vol 23 (8) ◽  
pp. 399-403 ◽  
Author(s):  
Niraj Pant ◽  
R C Murthy ◽  
S P Srivastava
Keyword(s):  
Drinking Water ◽  
Sodium Arsenite ◽  
Sperm Count ◽  
Prostate Gland ◽  
Reproductive Toxicity ◽  
Atomic Absorption Spectrophotometry ◽  
Reproductive Organs ◽  
Oral Exposure ◽  
Human Beings ◽  
Testicular Weight

The effect of chronic oral exposure to arsenic on male mouse testicular and accessory sex organ weights, sperm parameters and testicular marker enzymes was studied. In addition, the distribution of arsenic in reproductive organs was measured using atomic absorption spectrophotometry. Sodium arsenite administered to mice (Mus musculus) via drinking water at a dose of 53.39 βmol/L (4 ppm As) for 365 days caused a decrease in the absolute and relative testicular weight. However, epididymal and accessory sex organ weight was similar to control. The activities of marker testicular enzymes such as sorbitol dehydrogenase, acid phosphatase and 17β-hydroxysteroid dehydrogenase (17β-HSD) were significantly decreased, but those of lactate dehydrogenase and γ-glutamyl transpeptidase (γ-GT) were significantly increased. A decrease in sperm count and sperm motility, along with an increase in abnormal sperm, was observed in arsenite-exposed mice. A significant accumulation of arsenic in testes, epididymis, seminal vesicle and prostate gland was observed in treated animals. Thus long term exposure (365 days) at the dose level of 53.39 μmol/L sodium arsenite (4 ppm As), to which human beings are likely to be exposed via drinking water, may cause testicular and spermatotoxic effect.

scholarly journals Specific transgenerational imprinting effects of the endocrine disruptor methoxychlor on male gametes

Reproduction ◽  
2011 ◽  
Vol 141 (2) ◽  
pp. 207-216 ◽  
Author(s):  
Christelle Stouder ◽  
Ariane Paoloni-Giacobino
Keyword(s):  
Adult Male ◽  
Endocrine Disrupting Chemicals ◽  
Methylation Pattern ◽  
Imprinted Genes ◽  
Male Mice ◽  
Systematic Analysis ◽  
Adult Mice ◽  
Male Gametes ◽  
Pregnant Mice ◽  
Methylation Defects

Endocrine-disrupting chemicals (EDCs), among which methoxychlor (MXC), have been reported to affect the male reproductive system. This study evaluates the possible deleterious effects of MXC on imprinted genes. After administration of the chemical in adult male mice or in pregnant mice we analyzed by pyrosequencing possible methylation defects in two paternally imprinted (H19 and Meg3 (Gtl2)) and three maternally imprinted (Mest (Peg1), Snrpn, and Peg3) genes in the sperm and in the tail, liver, and skeletal muscle DNAs of the adult male mice and of the male offspring. MXC treatment of adult mice decreased the percentages of methylated CpGs of Meg3 and increased those of Mest, Snrpn, and Peg3 in the sperm DNA. MXC treatment of pregnant mice decreased the mean sperm concentrations by 30% and altered the methylation pattern of all the imprinted genes tested in the F1 offspring. In the latter case, MXC effects were transgenerational but disappeared gradually from F1 to F3. MXC did not affect imprinting in the somatic cells, suggesting that it exerts its damaging effects via the process of reprogramming that is unique to gamete development. A systematic analysis at the CpG level showed a heterogeneity in the CpG sensitivity to MXC. This observation suggests that not only DNA methylation but also other epigenetic modifications can explain the transgenerational effects of MXC. The reported effects of EDCs on human male spermatogenesis might be mediated by complex imprinting alterations analogous to those described in this study.

scholarly journals The androgen receptor is required for maintenance of bone mass in adult male mice

2019 ◽  
Vol 479 ◽  
pp. 159-169 ◽  
Author(s):  
Jianyao Wu ◽  
Petra Henning ◽  
Klara Sjögren ◽  
Antti Koskela ◽  
Juha Tuukkanen ◽  
...  
Keyword(s):  
Androgen Receptor ◽  
Bone Mass ◽  
Adult Male ◽  
Male Mice

scholarly journals Of mice and men-warning: Intact versus castrated adult male mice as xenograft hosts are equivalent to hypogonadal versus abiraterone treated aging human males, respectively

The Prostate ◽  
2013 ◽  
Vol 73 (12) ◽  
pp. 1316-1325 ◽  
Author(s):  
J.P. Michiel Sedelaar ◽  
Susan S. Dalrymple ◽  
John T. Isaacs
Keyword(s):  
Adult Male ◽  
Male Mice ◽  
Of Mice And Men

On the role of corticosterone in behavioral disorders, microbiota composition alteration and neuroimmune response in adult male mice subjected to maternal separation stress

2019 ◽  
Vol 66 ◽  
pp. 242-250 ◽  
Author(s):  
Hossein Amini-Khoei ◽  
Elaheh Haghani-Samani ◽  
Masoumeh Beigi ◽  
Amin Soltani ◽  
Gholam Reza Mobini ◽  
...  
Keyword(s):  
Behavioral Disorders ◽  
Adult Male ◽  
Maternal Separation ◽  
Microbiota Composition ◽  
Male Mice
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