Outcomes of acute basilar artery occlusion—real‐world experience in a middle‐income country

2021 ◽  
Author(s):  
Felipe Borelli Del Guerra ◽  
Guilherme Diogo Silva ◽  
Iago Navas Perissinoti ◽  
Livia Morais ◽  
Felipe Lorenzo Dornelas Marsolla ◽  
...  
Keyword(s):  
Basilar Artery ◽  
Real World ◽  
Artery Occlusion ◽  
Middle Income Country ◽  
Income Country ◽  
Basilar Artery Occlusion ◽  
Middle Income

Abstract 1122‐000068: Basilar Artery Occlusion Thrombectomy Between Evidence Based Medicine and the Real‐World Practice, Single Centre Experience

2021 ◽  
Vol 1 (S1) ◽  
Author(s):  
Islam El Malky ◽  
Ali Hendi ◽  
Hazem Abdelkhalek
Keyword(s):  
Clinical Outcome ◽  
Intracranial Hemorrhage ◽  
Basilar Artery ◽  
Real World ◽  
Artery Occlusion ◽  
Basilar Artery Occlusion ◽  
Early Reperfusion ◽  
Good Outcome ◽  
Symptomatic Intracranial Hemorrhage ◽  
Multiple Variables

Introduction : BAO (basilar artery occlusion) is well known by catastrophic outcomes whether death or disability in approximately 70 %. 1 Thrombectomy as an intervention in large vessel occlusion of anterior proximal circulation was approved after multiple RCTs and meta‐analyses. 2 In spite of two RCTs that appeared lately, there is still uncertainty about the effect of thrombectomy in BAO. 9, 10 Our study aims to report the outcome of BAO, as a further clue of MT effectiveness in BAO and variables affecting good outcome and mortality rate. Methods : We retrospectively collected the clinical and radiological data of 30 BAO patients treated in our center between 2016 and 2020. There is no limitation as regard age or presenting NIHHS. Twenty‐two patients who came to the emergency within 4.5 hours had I.V. thrombolytic therapy (73.3%). A favorable clinical outcome was considered if mRS ≤ 2. Angioplasty, stenting, or I.A thrombolysis were used as a rescue treatment. Symptomatic intracranial hemorrhage within two days after the initiation of treatment and mortality at 90 days were reported. The radiological outcome was assessed by modified Thrombolysis in Cerebral Infarction (mTICI) score where mTICI ≥ 2b or 3 at the end of the intervention was considered a favorable radiological result. Multiple variables were tested for their effect on favorable clinical outcomes and mortality (Table 1). Results : Among 30 patients, the mean age was 61.23 ± 16.81 years; 20/30 (66.7%) male. A favorable functional outcome was achieved in (40.7%). Successful revascularization was achieved in 26 patients (86.7 %). Four patients had procedural complications (13.3%). Symptomatic intracranial hemorrhage occurred in three cases (11%) and mortality at 90 days was 11 patients (36.7 %). The presenting NIHSS is the only predictor of mortality and the optimal cut‐off value for death was 15 with AUC = 0.758 (sensitivity 91 % and specificity 59%) and p‐value = 0.02. TOR (time of onset to recanalization) had no effect on the clinical outcome which is controversy with the paradigm of early reperfusion leading to a good outcome Conclusions : In spite of two RCSs approved no statistical difference between medical treatment and thrombectomy, thrombectomy is still an effective procedure in real‐world practice in selected cases. The presenting NIHSS is the only predictor of mortality in our studies. More studies are warranted to discover other predictors of BAO thrombectomy outcome to improve case selection and avoid futile recanalization.

Philadelphia-positive B-lymphoblastic leukemia in a middle-income country – a real-world multicenter cohort

2021 ◽  
pp. 106666
Author(s):  
Wellington F Silva ◽  
Alexandre Silverio ◽  
Bruno Kosa Lino Duarte ◽  
Thais Ferraz Aguiar ◽  
Rodrigo Miguel Bendlin ◽  
...  
Keyword(s):  
Real World ◽  
Lymphoblastic Leukemia ◽  
Middle Income Country ◽  
Income Country ◽  
Middle Income ◽  
Multicenter Cohort

Is immune tolerance induction conceivable in haemophilia with inhibitors in a low‐middle income country? Real‐world data from Tunisia

Haemophilia ◽  
2021 ◽  
Author(s):  
Emna Hammami ◽  
Wijden El Borgi ◽  
El Mahmoudi Hajer ◽  
Bouattour Houda ◽  
Mariem Achour ◽  
...  
Keyword(s):  
Immune Tolerance ◽  
Real World ◽  
Tolerance Induction ◽  
Middle Income Country ◽  
Income Country ◽  
Real World Data ◽  
Middle Income ◽  
Immune Tolerance Induction ◽  
World Data

scholarly journals PCN24 TYROSINE KINASE INHIBITORS: REAL WORLD EVIDENCE ABOUT HEALTH OUTCOMES IN A MIDDLE INCOME COUNTRY

2019 ◽  
Vol 22 ◽  
pp. S439
Author(s):  
J. Gonzalez ◽  
N. Castrillon ◽  
D. Lopera ◽  
C. Aguirre
Keyword(s):  
Tyrosine Kinase ◽  
Health Outcomes ◽  
Tyrosine Kinase Inhibitors ◽  
Real World ◽  
Kinase Inhibitors ◽  
Middle Income Country ◽  
Income Country ◽  
Middle Income ◽  
Real World Evidence

scholarly journals Management of advanced prostate cancer in a middle-income country: real-world consideration of the Advanced Prostate Cancer Consensus Conference 2017

2019 ◽  
Vol 124 (3) ◽  
pp. 373-382 ◽  
Author(s):  
Marniza Saad ◽  
Adlinda Alip ◽  
Jasmine Lim ◽  
Matin Mellor Abdullah ◽  
Flora Li Tze Chong ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Real World ◽  
Advanced Prostate Cancer ◽  
Consensus Conference ◽  
Middle Income Country ◽  
Income Country ◽  
Middle Income

scholarly journals Outcomes of diffuse large B-cell lymphoma in elderly patients – real-world experience from a middle-income country setting

2021 ◽  
Vol 15 ◽  
Author(s):  
Chandrayee Sarker ◽  
Vivek S Radhakrishnan ◽  
Paya Mandal ◽  
Jeevan Kumar ◽  
Saurabh Bhave ◽  
...  
Keyword(s):  
Elderly Patients ◽  
B Cell ◽  
Real World ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Middle Income Country ◽  
Income Country ◽  
Middle Income ◽  
Large B Cell Lymphoma ◽  
Large B Cell

Women break down the barriers to the Vietnamese social sciences and humanities

2019 ◽  
Author(s):  
Quan-Hoang Vuong
Keyword(s):  
Social Sciences ◽  
Gender Inequality ◽  
Middle Income Country ◽  
Women In Science ◽  
Income Country ◽  
The West ◽  
Middle Income ◽  
Social Sciences And Humanities ◽  
The Social ◽  
Low And Middle Income

Valian rightly made a case for better recognition of women in science during the Nobel week in October 2018 (Valian, 2018). However, it seems most published views about gender inequality in Nature focused on the West. This correspondence shifts the focus to women in the social sciences and humanities (SSH) in a low- and middle-income country (LMIC).

Endovascular Treatment for Acute Basilar Artery Occlusion: A Nationwide Prospective Registry

2019 ◽  
Author(s):  
Wenjie Zi ◽  
Zhongming Qiu ◽  
Deping Wu ◽  
Fengli Li ◽  
Hansheng Liu ◽  
...  
Keyword(s):  
Endovascular Treatment ◽  
Basilar Artery ◽  
Artery Occlusion ◽  
Basilar Artery Occlusion
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