Nitric oxide regulation of migrating motor complex: randomized trial of NG-monomethyl-l-arginine effects in relation to muscarinic and serotonergic receptor blockade

2015 ◽  
Vol 215 (2) ◽  
pp. 105-118 ◽  
Author(s):  
M. A. Halim ◽  
L. Gillberg ◽  
S. Boghus ◽  
M. Sundbom ◽  
U. Karlbom ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Randomized Trial ◽  
Migrating Motor Complex ◽  
Receptor Blockade ◽  
Motor Complex ◽  
Serotonergic Receptor

scholarly journals P085 Direct smooth muscle stimulatory effect of nitrergic inhibition by L-NMMA on the migrating motor complex modulated by muscarinic and 5-HT3 receptor blockade

2014 ◽  
Vol 8 ◽  
pp. S97
Author(s):  
M.A. Halim ◽  
S. Boghos ◽  
L. Gillberg ◽  
U. Karlbom ◽  
M. Sundbom ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Migrating Motor Complex ◽  
Receptor Blockade ◽  
Motor Complex

Sa2044 Direct Smooth Muscle Stimulatory Effect of L-NMMA on the Migrating Motor Complex Modulated by Muscarinic and 5-HT3 Receptor Blockade

2014 ◽  
Vol 146 (5) ◽  
pp. S-362
Author(s):  
Per M. Hellström ◽  
Md Abdul Halim ◽  
Sandy Boghos ◽  
Linda Gillberg ◽  
Magnus Sundbom ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Migrating Motor Complex ◽  
Receptor Blockade ◽  
Motor Complex

Involvement of neuronal nitric oxide synthase (nNOS) in the regulation of migrating motor complex (MMC) in sheep

2012 ◽  
Vol 192 (3) ◽  
pp. 352-358 ◽  
Author(s):  
M. Castro ◽  
J.M. Muñoz ◽  
M.P. Arruebo ◽  
M.D. Murillo ◽  
C. Arnal ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Neuronal Nitric Oxide Synthase ◽  
Migrating Motor Complex ◽  
Motor Complex ◽  
Oxide Synthase

scholarly journals Nitric oxide and the migrating motor complex

Gut ◽  
1999 ◽  
Vol 44 (1) ◽  
pp. 7 ◽  
Author(s):  
G LINDBERG
Keyword(s):  
Nitric Oxide ◽  
Migrating Motor Complex ◽  
Motor Complex

Nitric oxide regulates migrating motor complex cycling and its postprandial disruption

1993 ◽  
Vol 265 (4) ◽  
pp. G759-G766 ◽  
Author(s):  
S. K. Sarna ◽  
M. F. Otterson ◽  
R. P. Ryan ◽  
V. E. Cowles
Keyword(s):  
Nitric Oxide ◽  
Small Intestine ◽  
Methyl Ester ◽  
Motor Activity ◽  
Intravenous Infusion ◽  
No Synthase ◽  
Migrating Motor Complex ◽  
Fasting State ◽  
Motor Complex ◽  
Gastrointestinal Motor

We investigated the role of nitric oxide (NO) in the regulation of migrating motor complex (MMC) cycling during the fasting state and its postprandial disruption. Intravenous infusion of Nohgr-nitro-l-arginine methyl ester (l-NAME) first produced a premature MMC and then disrupted MMC cycling for the rest of the day. The cycle length of the MMCs was significantly shorter than the control on the 2nd, 3rd, and 4th day after l-NAME infusion. The gastric cyclic motor activity (CMA) did not usually exhibit a premature cycle on the day of l-NAME infusion but was disrupted by l-NAME infusion; the duration of CMA disruption in the stomach was significantly longer than that of MMC disruption in the small intestine. Infusion of Nohgr-nitro-l-arginine (l-NNA) exhibited similar effects. The intravenous infusion of l-NAME also significantly shortened the duration of MMC disruption by a meal. l-Arginine alone had no significant effect on gastrointestinal motor activity during the fasting or the fed state, but when infused with l-NAME, it blocked the effects of NO synthase inhibition. Angiotensin II increased the mean arterial pressure to a level similar to that produced by l-NAME but had no significant effect on the fasting or the fed pattern of gastrointestinal motor activity. We conclude that NO containing nonadrenergic noncholinergic (NANC) neurons play a significant role in regulating MMC and CMA cycling during the fasting state and their disruption by a meal. However, NO may not be the only NANC neurotransmitter to inhibit contractions in the gut; phase I activity in the small intestine persisted during NO synthase inhibition by l-NAME or l-NNA. nonadrenergic noncholinergic neurons; cyclic motor activity: Nohgr-nitro-l-arginine methyl ester; Nohgr-nitro-l-arginine; vasoactive intestinal peptide; cholecystokinin Submitted on November 30, 1992 Accepted on June 3, 1993

Endogenous motilin, but not ghrelin plasma levels fluctuate in accordance with gastric phase III activity of the migrating motor complex in man

2014 ◽  
Vol 27 (1) ◽  
pp. 63-71 ◽  
Author(s):  
E. Deloose ◽  
R. Vos ◽  
M. Corsetti ◽  
I. Depoortere ◽  
J. Tack
Keyword(s):  
Plasma Levels ◽  
Migrating Motor Complex ◽  
Phase Iii ◽  
Motor Complex

scholarly journals The Relationship Between Feed Intake and Frequency of the Migrating Motor Complex in Domestic Turkeys: Is There a Cephalic Phase?

1991 ◽  
Vol 70 (8) ◽  
pp. 1758-1762
Author(s):  
JAN SCHLAMP ◽  
GARY E. DUKE ◽  
ORAL A. EVANSON
Keyword(s):  
Feed Intake ◽  
Migrating Motor Complex ◽  
Motor Complex ◽  
Cephalic Phase ◽  
The Relationship

Comparative effects of glutamate receptor blockade and of nitric oxide synthase inhibition in transient focal cerebral ischemia in rats

1997 ◽  
Vol 42 (1) ◽  
pp. 19S
Author(s):  
R.G. Boulu ◽  
I. Margaill ◽  
S. Parmentier ◽  
J. Callebert ◽  
M. Allix ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Cerebral Ischemia ◽  
Nitric Oxide Synthase ◽  
Glutamate Receptor ◽  
Focal Cerebral Ischemia ◽  
Receptor Blockade ◽  
Transient Focal Cerebral Ischemia ◽  
Oxide Synthase

scholarly journals Inflammatory Mediators in Tracheal Aspirates of Preterm Infants Participating in a Randomized Trial of Inhaled Nitric Oxide

PLoS ONE ◽  
2017 ◽  
Vol 12 (1) ◽  
pp. e0169352 ◽  
Author(s):  
Mandy Laube ◽  
Elena Amann ◽  
Ulrike Uhlig ◽  
Yang Yang ◽  
Hans W. Fuchs ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Randomized Trial ◽  
Preterm Infants ◽  
Inflammatory Mediators ◽  
Inhaled Nitric Oxide ◽  
Tracheal Aspirates
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