scholarly journals Global variation in freshwater physico‐chemistry and its influence on chemical toxicity in aquatic wildlife

2021 ◽  
Author(s):  
João Paulo S. Pinheiro ◽  
Fredric M. Windsor ◽  
Rod W. Wilson ◽  
Charles R. Tyler
Keyword(s):  
Chemical Toxicity ◽  
Global Variation ◽  
Aquatic Wildlife

Global Variation of ULF Geomagnetic Fields and Detection of Anomalous Changes at a Certain Observatory using Reference Data

2011 ◽  
Vol 131 (9) ◽  
pp. 698-704
Author(s):  
Katsumi Hattori ◽  
Peng Han ◽  
Qinghua Huang
Keyword(s):  
Reference Data ◽  
Global Variation ◽  
Geomagnetic Fields

Predicting Chemical Toxicity from Proteomics and Computational Chemistry

2008 ◽  
Author(s):  
Subhash C. Basak
Keyword(s):  
Computational Chemistry ◽  
Chemical Toxicity

scholarly journals The Role of the Human Microbiome in Chemical Toxicity

2019 ◽  
Vol 38 (4) ◽  
pp. 251-264 ◽  
Author(s):  
Jason M. Koontz ◽  
Blair C. R. Dancy ◽  
Cassandra L. Horton ◽  
Jonathan D. Stallings ◽  
Valerie T. DiVito ◽  
...  
Keyword(s):  
Health Outcomes ◽  
Human Microbiome ◽  
Chemical Exposure ◽  
Environmental Chemicals ◽  
Microbial Interactions ◽  
World Population ◽  
Toxic Exposure ◽  
Chemical Toxicity ◽  
Microbial Enzymes ◽  
Overwhelming Evidence

There is overwhelming evidence that the microbiome must be considered when evaluating the toxicity of chemicals. Disruption of the normal microbial flora is a known effect of toxic exposure, and these disruptions may lead to human health effects. In addition, the biotransformation of numerous compounds has been shown to be dependent on microbial enzymes, with the potential for different host health outcomes resulting from variations in the microbiome. Evidence suggests that such metabolism of environmental chemicals by enzymes from the host's microbiota can affect the toxicity of that chemical to the host. Chemical-microbial interactions can be categorized into two classes: Microbiome Modulation of Toxicity (MMT) and Toxicant Modulation of the Microbiome (TMM). MMT refers to transformation of a chemical by microbial enzymes or metabolites to modify the chemical in a way that makes it more or less toxic. TMM is a change in the microbiota that results from a chemical exposure. These changes span a large magnitude of effects and may vary from microbial gene regulation, to inhibition of a specific enzyme, to the death of the microbes. Certain microbiomes or microbiota may become associated with different health outcomes, such as resistance or susceptibility to exposure to certain toxic chemicals, the ability to recover following a chemical-induced injury, the presence of disease-associated phenotypes, and the effectiveness of immune responses. Future work in toxicology will require an understanding of how the microbiome interacts with toxicants to fully elucidate how a compound will affect a diverse, real-world population.

scholarly journals A peep into the state of ground water quality in the district of Tiruvannamalai, Tamil Nadu, India, from a radiological and chemical toxicity perspective

2021 ◽  
Vol 11 (5) ◽  
Author(s):  
Durai Ganesh ◽  
G. Senthilkumar ◽  
P. Eswaran ◽  
M. Balakrishnan ◽  
S. N. Bramha ◽  
...  
Keyword(s):  
Water Quality ◽  
Ground Water ◽  
Water Samples ◽  
Tamil Nadu ◽  
Potable Water ◽  
Uranium Concentration ◽  
The State ◽  
Chemical Toxicity ◽  
Ground Water Quality ◽  
Led Fluorimeter

AbstractUranium concentration in the ground water samples from the district of Tiruvannamalai, Tamil Nadu, was measured using an LED fluorimeter. All the samples were qualified as potable water from the radiological perspective. Though some samples showed mild chemical toxicity, they are still safe for ingestion. Different risk coefficients were calculated, and they were compared with recommended safety limits specified by various agencies. Software tools such as QGIS 15, GraphPad Prism 8 and Surfer 15 were employed for developing maps and plots.

scholarly journals Global variation in SARS-CoV-2 proteome and its implication in pre-lockdown emergence and dissemination of 5 dominant SARS-CoV-2 clades

2021 ◽  
pp. 104973
Author(s):  
L. Ponoop Prasad Patro ◽  
Chakkarai Sathyaseelan ◽  
Patil Pranita Uttamrao ◽  
Thenmalarchelvi Rathinavelan
Keyword(s):  
Global Variation

scholarly journals Chemical Contamination Pathways and the Food Safety Implications along the Various Stages of Food Production: A Review

2021 ◽  
Vol 18 (11) ◽  
pp. 5795
Author(s):  
Kgomotso Lebelo ◽  
Ntsoaki Malebo ◽  
Mokgaotsa Jonas Mochane ◽  
Muthoni Masinde
Keyword(s):  
Food Safety ◽  
Food Production ◽  
Food Industry ◽  
Food Packaging ◽  
Agricultural Sector ◽  
Negative Impact ◽  
Anthropogenic Factors ◽  
Chemical Contamination ◽  
Chemical Toxicity ◽  
Chemical Substances

Historically, chemicals exceeding maximum allowable exposure levels have been disastrous to underdeveloped countries. The global food industry is primarily affected by toxic chemical substances because of natural and anthropogenic factors. Food safety is therefore threatened due to contamination by chemicals throughout the various stages of food production. Persistent Organic Pollutants (POPs) in the form of pesticides and other chemical substances such as Polychlorinated Biphenyls (PCBs) have a widely documented negative impact due to their long-lasting effect on the environment. This present review focuses on the chemical contamination pathways along the various stages of food production until the food reaches the consumer. The contamination of food can stem from various sources such as the agricultural sector and pollution from industrialized regions through the air, water, and soil. Therefore, it is imperative to control the application of chemicals during food packaging, the application of pesticides, and antibiotics in the food industry to prevent undesired residues on foodstuffs. Ultimately, the protection of consumers from food-related chemical toxicity depends on stringent efforts from regulatory authorities both in developed and underdeveloped nations.

scholarly journals Broad diversity of bacteria degrading 17ß-estradiol-3-sulfate isolated from river sediment and biofilm at a wastewater treatment plant discharge

2021 ◽  
Author(s):  
Tamara Mainetti ◽  
Marilena Palmisano ◽  
Fabio Rezzonico ◽  
Blaž Stres ◽  
Susanne Kern ◽  
...  
Keyword(s):  
Wastewater Treatment ◽  
River Sediment ◽  
Wastewater Treatment Plants ◽  
Treatment Plant ◽  
Aquatic Environments ◽  
Bacterial Isolates ◽  
Degrading Bacteria ◽  
17Β Estradiol ◽  
Aquatic Wildlife ◽  
Harmful Effects

AbstractConjugated estrogens, such as 17β-estradiol-3-sulfate (E2-3S), can be released into aquatic environments through wastewater treatment plants (WWTP). There, they are microbiologically degraded into free estrogens, which can have harmful effects on aquatic wildlife. Here, the degradation of E2-3S in environmental samples taken upstream, downstream and at the effluent of a WWTP was assessed. Sediment and biofilm samples were enriched for E2-3S-degrading microorganisms, yielding a broad diversity of bacterial isolates, including known and novel degraders of estrogens. Since E2-3S-degrading bacteria were also isolated in the sample upstream of the WWTP, the WWTP does not influence the ability of the microbial community to degrade E2-3S.

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