Fish Oil Supplementation in Pregnancy and Neurodevelopment in Childhood—A Randomized Clinical Trial

2021 ◽  
Author(s):  
Laerke Sass ◽  
Elín Bjarnadóttir ◽  
Jakob Stokholm ◽  
Bo Chawes ◽  
Rebecca K. Vinding ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Fish Oil ◽  
Randomized Clinical Trial ◽  
Fish Oil Supplementation ◽  
In Pregnancy

scholarly journals Effect of fish oil supplementation in pregnancy on bone, lean, and fat mass at six years: randomised clinical trial

BMJ ◽  
2018 ◽  
pp. k3312 ◽  
Author(s):  
Rebecca Kofod Vinding ◽  
Jakob Stokholm ◽  
Astrid Sevelsted ◽  
Tobias Sejersen ◽  
Bo L Chawes ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Fish Oil ◽  
Fat Mass ◽  
Randomised Clinical Trial ◽  
Fish Oil Supplementation ◽  
In Pregnancy

scholarly journals Gene Expression and Biological Pathways in Tissue of Men with Prostate Cancer in a Randomized Clinical Trial of Lycopene and Fish Oil Supplementation

PLoS ONE ◽  
2011 ◽  
Vol 6 (9) ◽  
pp. e24004 ◽  
Author(s):  
Mark Jesus M. Magbanua ◽  
Ritu Roy ◽  
Eduardo V. Sosa ◽  
Vivian Weinberg ◽  
Scott Federman ◽  
...  
Keyword(s):  
Gene Expression ◽  
Prostate Cancer ◽  
Clinical Trial ◽  
Fish Oil ◽  
Randomized Clinical Trial ◽  
Biological Pathways ◽  
Fish Oil Supplementation

scholarly journals A phase IV, multi-centre, randomized clinical trial comparing two pertussis-containing vaccines in pregnant women in England and vaccine responses in their infants

BMC Medicine ◽  
2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Christine Elizabeth Jones ◽  
Anna Calvert ◽  
Jo Southern ◽  
Mary Matheson ◽  
Nick Andrews ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Pertussis Toxin ◽  
Geometric Mean ◽  
Control Group ◽  
Primary Immunization ◽  
Link Type ◽  
In Pregnancy ◽  
Pertussis Antigens ◽  
Phase Iv

Abstract Background Pertussis vaccines containing three or five pertussis antigens are recommended in pregnancy in many countries, but no studies have compared the effect on infants’ antigen-specific immunoglobulin G (IgG) concentrations. The aim of this study was to compare anti-pertussis IgG responses following primary immunization in infants of mothers vaccinated with TdaP5-IPV (low dose diphtheria toxoid, tetanus toxoid, acellular pertussis [five antigens] and inactivated polio) or TdaP3-IPV in pregnancy (three pertussis antigens). Methods This multi-centre phase IV randomized clinical trial was conducted in a tertiary referral centre and primary care sites in England. Women were randomized to receive TdaP5-IPV (n = 77) or TdaP3-IPV (n = 77) at 28–32 gestational weeks. A non-randomized control group of 44 women who had not received a pertussis-containing vaccine in pregnancy and their 47 infants were enrolled post-partum. Results Following infant primary immunization, there was no difference in the geometric mean concentrations (GMCs) of anti-pertussis toxin, filamentous haemagglutinin or pertactin IgG between infants born to women vaccinated with TdaP5-IPV (n = 67) or TdaP3-IPV (n = 63). However, the GMC of anti-pertussis toxin IgG was lower in infants born to TdaP5-IPV- and TdaP3-IPV-vaccinated mothers compared to infants born to unvaccinated mothers (n = 45) (geometric mean ratio 0.71 [0.56–0.90] and 0.78 [0.61–0.98], respectively); by 13 months of age, this difference was no longer observed. Conclusion Blunting of anti-pertussis toxin IgG response following primary immunization occurs in infants born to women vaccinated with TdaP5-IPV and TdaP3-IPV, with no difference between maternal vaccines. The blunting effect had resolved by 13 months of age. These results may be helpful for countries considering which pertussis-containing vaccine to recommend for use in pregnancy. Trial registration ClinicalTrials.gov, NCT02145624, registered 23 May 2014

scholarly journals Metformin versus Insulin in the Management of Pre-Gestational Diabetes Mellitus in Pregnancy and Gestational Diabetes Mellitus at the Korle Bu Teaching Hospital: A Randomized Clinical Trial

PLoS ONE ◽  
2015 ◽  
Vol 10 (5) ◽  
pp. e0125712 ◽  
Author(s):  
Titus Beyuo ◽  
Samuel Amenyi Obed ◽  
Kenneth Kweku Adjepong-Yamoah ◽  
Kwasi Agyei Bugyei ◽  
Samuel Antwi Oppong ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Clinical Trial ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Randomized Clinical Trial ◽  
Teaching Hospital ◽  
In Pregnancy

scholarly journals Fish-oil supplementation in pregnancy, child metabolomics and asthma risk

EBioMedicine ◽  
2019 ◽  
Vol 46 ◽  
pp. 399-410 ◽  
Author(s):  
Daniela Rago ◽  
Morten A. Rasmussen ◽  
Kathleen A. Lee-Sarwar ◽  
Scott T. Weiss ◽  
Jessica Lasky-Su ◽  
...  
Keyword(s):  
Fish Oil ◽  
Asthma Risk ◽  
Fish Oil Supplementation ◽  
In Pregnancy

Relapse Prevention Among Women Who Stop Smoking Early in Pregnancy: A Randomized Clinical Trial of a Self-help Intervention

1995 ◽  
Vol 11 (3) ◽  
pp. 178-184 ◽  
Author(s):  
Daniel H. Ershoff ◽  
Virginia P. Quinn ◽  
Patricia Dolan Mullen
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Relapse Prevention ◽  
Self Help ◽  
Stop Smoking ◽  
In Pregnancy

scholarly journals Fish oil supplementation for primary prevention of atrial fibrillation after coronary artery bypass graft surgery: A randomized clinical trial

2017 ◽  
Vol 42 ◽  
pp. 41-48 ◽  
Author(s):  
Ali Vasheghani Farahani ◽  
Awat Yousefi Azar ◽  
Hamid Reza Goodarzynejad ◽  
Elnaz Khorrami ◽  
Mohammad Javad Hosseinzadeh-Attar ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Clinical Trial ◽  
Coronary Artery ◽  
Primary Prevention ◽  
Coronary Artery Bypass Graft ◽  
Fish Oil ◽  
Artery Bypass ◽  
Bypass Graft ◽  
Artery Bypass Graft ◽  
Fish Oil Supplementation

scholarly journals The impact of the active management of risk in pregnancy at term on birth outcomes: a randomized clinical trial

2008 ◽  
Vol 198 (5) ◽  
pp. 511.e1-511.e15 ◽  
Author(s):  
James M. Nicholson ◽  
Samuel Parry ◽  
Aaron B. Caughey ◽  
Sarah Rosen ◽  
Allison Keen ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Birth Outcomes ◽  
Active Management ◽  
The Impact ◽  
In Pregnancy ◽  
Management Of Risk

scholarly journals Adapting iron dose supplementation in pregnancy for greater effectiveness on mother and child health: protocol of the ECLIPSES randomized clinical trial

2014 ◽  
Vol 14 (1) ◽  
Author(s):  
Victoria Arija ◽  
Francesc Fargas ◽  
Gemma March ◽  
Susana Abajo ◽  
Josep Basora ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Child Health ◽  
Randomized Clinical Trial ◽  
Mother And Child Health ◽  
Mother And Child ◽  
And Child Health ◽  
In Pregnancy

Analysis of hospital cost outcome of DHA-rich fish-oil supplementation in pregnancy: Evidence from a randomized controlled trial

2015 ◽  
Vol 102-103 ◽  
pp. 5-11 ◽  
Author(s):  
Sharmina Ahmed ◽  
Maria Makrides ◽  
Nicholas Sim ◽  
Andy McPhee ◽  
Julie Quinlivan ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Fish Oil ◽  
Hospital Cost ◽  
Controlled Trial ◽  
Randomized Controlled ◽  
Fish Oil Supplementation ◽  
In Pregnancy
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