Aortic valve cusp aneurysm as a result of blood culture‐negative infective endocarditis, interesting echocardiographic and surgical images

2020 ◽  
Vol 37 (3) ◽  
pp. 469-471 ◽  
Author(s):  
Shokoufeh Hajsadeghi ◽  
Mahboubeh Pazoki ◽  
Marziyeh Pakbaz ◽  
Sam Zeraatian ◽  
Mohammad Amin Zaeim
Keyword(s):  
Infective Endocarditis ◽  
Aortic Valve ◽  
Blood Culture ◽  
Culture Negative

Blood culture-negative infective endocarditis: a worse outcome? Results from a large multicentre retrospective Spanish cohort study

2021 ◽  
pp. 1-9
Author(s):  
Lorenzo Roberto Suardi ◽  
Arístides de Alarcón ◽  
María Victoria García ◽  
Antonio Plata Ciezar ◽  
Carmen Hidalgo Tenorio ◽  
...  
Keyword(s):  
Cohort Study ◽  
Infective Endocarditis ◽  
Blood Culture ◽  
Culture Negative ◽  
Spanish Cohort

scholarly journals Blood culture-negative endocarditis caused by Tropheryma whipplei: a case report of Whipple’s endocarditis

2021 ◽  
Author(s):  
Silke Knol ◽  
Rogier L Nijhuis ◽  
Felix Geeraedts ◽  
Gerard Linssen
Keyword(s):  
Aortic Valve ◽  
Blood Culture ◽  
Tropheryma Whipplei ◽  
Polymerase Chain Reaction Test ◽  
Reaction Test ◽  
Polymerase Chain ◽  
Diagnostic Clue ◽  
Chain Reaction Test ◽  
Culture Negative

Case description: A 67-year-old man was admitted with progressive heart failure, due to blood culture-negative endocarditis of the aortic valve. In early course, urgent aortic valve replacement was needed. A polymerase chain reaction test (PCR) on samples of the explanted aortic valve revealed Tropheryma whipplei. He received ceftriaxone, followed by long-term co-trimoxazole. Recent arthralgia may have been a diagnostic clue. Conclusion: Whipple’s endocarditis should be assessed in patients with arthralgia and blood culture-negative endocarditis (BCNIE).

scholarly journals Cardiobacterium hominis and Cardiobacterium valvarum: Two Case Stories with Infective Episodes in Pacemaker Treated Patients

2016 ◽  
Vol 10 (1) ◽  
pp. 183-187 ◽  
Author(s):  
Tina Bennett Bonavent ◽  
Xiaohui Chen Nielsen ◽  
Kjeld Skødebjerg Kristensen ◽  
Nikolaj Ihlemann ◽  
Claus Moser ◽  
...  
Keyword(s):  
Infective Endocarditis ◽  
Aortic Valve ◽  
Blood Culture ◽  
Disease Severity ◽  
Bicuspid Aortic Valve ◽  
Case Reports ◽  
Cardiac Devices ◽  
Etiologic Agents ◽  
Case Stories

Introduction: Cardiobacterium hominis and Cardiobacterium valvarum are well known, though rare, etiologic agents of infective endocarditis. Cardiac devices are increasingly implanted. Case Reports: Two cases of infective episodes in pacemaker (PM) treated patients with respectively C. hominis and C. valvarum are presented. In one case blood-culture bottles yielded growth of C. hominis at two episodes with two years apart. At the second episode a vegetation was recognized at the PM lead and the PM device and lead was removed. In the C. valvarum case, echocardiography revealed a bicuspid aortic valve with severe regurgitation and a more than 1 cm sized vegetation. Conclusion: The cases illustrate the diversity in disease severity by Cardiobacterium species. Careful follow up has to be performed in order not to overlook a relatively silent relapsing infection.

scholarly journals A Curious Case of Blood-Culture-Negative Infective Endocarditis

2018 ◽  
Vol 32 (1) ◽  
pp. e3-e5
Author(s):  
Satoru Fujii ◽  
Elena Tugaleva ◽  
Michael W.A. Chu ◽  
Daniel Bainbridge
Keyword(s):  
Infective Endocarditis ◽  
Blood Culture ◽  
Culture Negative

scholarly journals Evaluation of Laboratory Predictors for In-Hospital Mortality in Infective Endocarditis and Negative Blood Culture Pattern Characteristics

Pathogens ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 551
Author(s):  
Ana-Maria Buburuz ◽  
Antoniu Petris ◽  
Irina Iuliana Costache ◽  
Igor Jelihovschi ◽  
Catalina Arsenescu-Georgescu ◽  
...  
Keyword(s):  
Infective Endocarditis ◽  
Blood Culture ◽  
Blood Cell ◽  
Hospital Mortality ◽  
Cell Count ◽  
Neutrophil Count ◽  
Hospital Death ◽  
Blood Cell Count ◽  
Positive Groups ◽  
Culture Negative

Objective: This study aimed to identify possible differences between blood culture-negative and blood culture-positive groups of infective endocarditis (IE), and explore the associations between biological parameters and in-hospital mortality. Methods: This was a retrospective study of patients hospitalized for IE between 2007 and 2017. Epidemiological, clinical and paraclinical characteristics, by blood culture-negative and positive groups, were collected. The best predictors of in-hospital mortality based on the receiver-operating characteristic (ROC) analysis and AUC (area under the curve) results were identified. Results: A total of 126 IE patients were included, 54% with negative blood cultures at admission. Overall, the in-hospital mortality was 28.6%, higher in the blood culture-negative than positive group (17.5% vs. 11.1%, p = 0.207). A significant increase in the Model for End-Stage Liver Disease Excluding International Normalized Ratio (MELD-XI) score was observed in the blood culture-negative group (p = 0.004), but no baseline characteristics differed between the groups. The best laboratory predictors of in-hospital death in the total study group were the neutrophil count (AUC = 0.824), white blood cell count (AUC = 0.724) and MELD-XI score (AUC = 0.700). Conclusion: Classic laboratory parameters, such as the white blood cell count and neutrophil count, were associated with in-hospital mortality in infective endocarditis. In addition, MELD-XI was a good predictor of in-hospital death.

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