Family history of alcoholism in the United States: prevalence and demographic characteristics

BackgroundBoth a family history of alcoholism and migration-related factors like US v. foreign nativity increase the risk for developing alcohol use disorders in Hispanic Americans. For this study, we integrated these two lines of research to test whether the relationship between familial alcoholism and alcohol dependence changes with successive generations in the United States.MethodData were from the waves 1 and 2 National Epidemiologic Survey on Alcohol and Related Conditions (NESARC). Subjects self-identified Hispanic ethnicity (N = 4122; n = 1784 first, n = 1169 second, and n = 1169 third or later generation) and reported ever consuming ⩾12 drinks in a 1-year period. A family history of alcoholism was assessed in first- and second-degree relatives. Analyses predicting the number of alcohol dependence symptoms were path models.ResultsAlcohol dependence symptoms were associated with a stronger family history of alcoholism and later generational status. There was a significant interaction effect between familial alcoholism and generational status; the relationship of familial alcoholism with alcohol dependence symptoms increased significantly with successive generations in the United States, more strongly in women than men. Acculturation partially mediated the interaction effect between familial alcoholism and generational status on alcohol dependence, although not in the expected direction.ConclusionsFamilial alcoholism interacted with generational status in predicting alcohol dependence symptoms in US Hispanic drinkers. This relationship suggests that heritability for alcoholism is influenced by a higher-order environmental factor, likely characterized by a relaxing of social restrictions on drinking.

Download Full-text

Population Prevalence of First-Degree Family History of Breast and Ovarian Cancer in the United States: Implications for Genetic Testing§

The Open Health Services and Policy Journal ◽

10.2174/1874924000801010034 ◽

2008 ◽

Vol 1 (1) ◽

pp. 34-37 ◽

Cited By ~ 4

Author(s):

Ingrid J. Hall ◽

Andrea Middlebrooks ◽

Steven S. Coughlin

Keyword(s):

United States ◽

Ovarian Cancer ◽

Genetic Testing ◽

Family History ◽

The United States ◽

Breast And Ovarian Cancer ◽

Population Prevalence ◽

History Of

Download Full-text

Abstract 145: Differences in Presenting Symptoms of Fibromuscular Dysplasia Patients With Family History of Fibromuscular Dysplasia, Arterial Aneurysm, Dissection, or Sudden Death: A Report from the United States Registry for Fibromuscular Dysplasia

Circulation Cardiovascular Quality and Outcomes ◽

10.1161/circoutcomes.9.suppl_2.145 ◽

2016 ◽

Vol 9 (suppl_2) ◽

Author(s):

Joon B Kim ◽

Steven T Heidt ◽

Xiaokui Gu ◽

Heather L Gornik ◽

Jeffrey W Olin ◽

...

Keyword(s):

United States ◽

Family History ◽

Sudden Death ◽

Fibromuscular Dysplasia ◽

The United States ◽

Categorical Variables ◽

Arterial Aneurysm ◽

Presenting Symptoms ◽

History Of ◽

Student’S T

Introduction: Fibromuscular dysplasia (FMD) is a non-atherosclerotic, non-inflammatory vascular disorder which may lead to stenosis, tortuosity, dissection, or aneurysm in any arterial bed. Some affected patients have a family history of FMD, arterial aneurysm (AA), arterial dissection (AD) or sudden death (SD), supporting a genetic predisposition. The clinical characteristics of this patient population have not been described. We hypothesized that patients with a family history of FMD, AA, AD, or SD would present differently than those without. Methods: By July 2014, of 880 patients enrolled in the United States Registry for FMD, 295 had a family history of FMD, AA, AD, or SD. These patients were compared to those without family history, analyzing demographics, symptoms at time of diagnosis, and vascular bed involvement. Student’s t-tests and Fisher’s exact tests were used to analyze continuous and categorical variables, respectively. Results: Patients with a family history of FMD, AA, AD, or SD were younger at diagnosis and more likely to experience CNS symptoms (headache, tinnitus, neck pain), post-prandial abdominal pain, as well as stroke and TIA at time of diagnosis. They also exhibited a trend toward more frequent carotid dissection (Table 1). Conclusions: Patients with a family history of FMD, arterial aneurysm (AA), dissection (AD), or sudden death (SD) more commonly had extracranial arterial bed complications, and experienced symptoms related to this vascular territory at time of diagnosis. These results suggest that FMD may present differently in those with this family history.

Download Full-text

Subclinical tremor in normal controls with versus without a family history of essential tremor: data from the United States and Turkey

European Journal of Neurology ◽

10.1111/j.1468-1331.2009.02875.x ◽

2009 ◽

Vol 17 (4) ◽

pp. 607-611 ◽

Cited By ~ 5

Author(s):

E. D. Louis ◽

O. Dogu ◽

R. Ottman

Keyword(s):

United States ◽

Family History ◽

Essential Tremor ◽

The United States ◽

History Of ◽

Normal Controls

Download Full-text

Family History of Cancer and Risk of Lung Cancer among Lifetime Nonsmoking Women in the United States

American Journal of Epidemiology ◽

10.1093/oxfordjournals.aje.a008783 ◽

1996 ◽

Vol 143 (6) ◽

pp. 535-542 ◽

Cited By ~ 66

Author(s):

A. H. Wu ◽

E. T. H. Fontham ◽

P. Reynolds ◽

R. S. Greenberg ◽

P. Buffler ◽

...

Keyword(s):

United States ◽

Lung Cancer ◽

Family History ◽

The United States ◽

Family History Of Cancer ◽

History Of ◽

History Of Cancer

Download Full-text

A COMPARATIVE STUDY OF MOTIVATION AND ENTREPRENEURIAL INTENTIONALITY: CHINESE AND AMERICAN PERSPECTIVES

Journal of Developmental Entrepreneurship ◽

10.1142/s1084946710001506 ◽

2010 ◽

Vol 15 (02) ◽

pp. 187-204 ◽

Cited By ~ 18

Author(s):

ROBERT PLANT ◽

JEN REN

Keyword(s):

United States ◽

Family History ◽

Family Background ◽

The United States ◽

Business Programs ◽

Self Employment ◽

Entrepreneurial Intent ◽

History Of ◽

Preference Inventory ◽

The Impact

In this paper, we compare the intentionality of students in graduate business programs in the United States and China toward becoming entrepreneurs. We utilize Amabile's Work Preference Inventory (WPI) to examine the motivational dimension of entrepreneurial intentionality and the Theory of Planned Behavior (TPB) to compare the impact of gender and family history of self-employment on employment intentionality. Our results suggest there is a positive relationship with entrepreneurial intent in both the intrinsic challenge characteristic and extrinsic compensation characteristic. Results also suggest the intrinsic enjoyment characteristic and extrinsic outward characteristic are negatively correlated to self-employment. In addition, the study found that males in China exhibited a significantly greater intentionality toward self-employment than females did. We also found that entrepreneurial intentionality is stronger in the U.S. study group than in the China group for those with prior self-employment experience, as well as when they have a background that includes a family history of self-employment. However, when there is no family background of self-employment, the Chinese show greater intentionality to become self-employed than the group located in the United States.

Download Full-text