scholarly journals Non-steroidal anti-inflammatory drugs and hypertension in the elderly: a community-based cross-sectional study.

1993 ◽  
Vol 35 (5) ◽  
pp. 455-459 ◽  
Author(s):  
AG Johnson ◽  
LA Simons ◽  
J Simons ◽  
Y Friedlander ◽  
J McCallum
2019 ◽  
Author(s):  
Nuru Abdu ◽  
Samuel Teweldemedhin ◽  
Asmerom Mosazghi ◽  
Luwam Asfaha ◽  
Makda Teshale ◽  
...  

Abstract Introduction: Globally, non-steroidal anti-inflammatory drugs (NSAIDs) usage in the elderly with chronic pain has been reported as frequent. Though it is fundamental in maintaining their quality of life, the risk of polypharmacy, drug interactions and adverse effects is of paramount importance as the elderly usually require multiple medications for their co-morbidities. If prescriptions are not appropriately monitored and managed, they are likely to expose patients to serious drug interactions and potentially fatal adverse effects. Thus, the objective of the study was to assess the appropriateness of NSAIDs use and incidence of NSAIDs related potential interactions in elderly. Methods: A descriptive cross-sectional study was conducted among elderly out-patients (aged 60 and above) who visited three hospitals in Asmara between August 22 and September 29, 2018. The sampling design was two-stage random sampling and data was collected using a questionnaire, exit interview and by abstracting information from patients’ clinical cards. Descriptive and analytical statistics including chi-square test and logistic regression were employed using SPSS. Results: A total of 285 elderly respondents were enrolled in the study with similar male to female ratio. One in four of all respondents were chronic NSAIDs users, of which 74.6% were not prescribed prophylactic gastro-protective agents (GPAs). About 20% of the elderly were involved in polypharmacy and nearly all of the encountered potential NSAIDs related interactions (n=322) with prescribed drugs were moderate. Diabetes and hypertension were significantly associated with chronic NSAIDs use (OR=3, 95% CI: 1.54, 5.84; OR=9.99, 95% CI: 4.46, 22.38) and incidence of drug interactions (OR=3.95, 95%CI: 1.92, 8.13; OR=3.12, 95%CI: 1.81, 5.33) while diabetes and cardiac problem were significantly associated with incidence of polypharmacy (OR=4.33, 95% CI: 2.36, 7.96; OR=3.56, 95% CI: 1.05, 12.11). Conclusion: Though the overall reflection of prescription pattern of NSAIDs during the study period was almost satisfactory, gastro-protective agents were poorly prescribed as a prophylaxis.


2016 ◽  
Vol 105 (11) ◽  
pp. e543-e548 ◽  
Author(s):  
Nathalie Bertille ◽  
Gérard Pons ◽  
Elisabeth Fournier-Charrière ◽  
Babak Khoshnood ◽  
Martin Chalumeau

Author(s):  
K. Kriti Bhat ◽  
M. C. Yadavannavar

Background: With the increasing life expectancy, the population around the world is growing old at a higher rate. Ensuring their quality of life and addressing their health care needs is a major challenge ahead. Elderly women are more vulnerable and there is a dearth for information regarding their health problems in India. Therefore, this study was undertaken focusing on the health problems of rural elderly women. The objective of the study was to assess the morbidity pattern of rural elderly women.Methods: A community based cross-sectional study was conducted in the rural field practice area of Shri B M Patil Medical College, Vijayapura from November 2015 to February 2016. A house-to-house survey was done and 200 women aged ≥60 years were included in the study. They were interviewed using pretested and predesigned questionnaire after obtaining informed consent. Information regarding demographic profile, present or past illness, economic history and physical activity of daily living were collected. Analysis was done using SPSS v.16 and data was represented using proportions and percentages.Results: Majority of the participants were illiterate (96.4%). Most (83.6%) of them were financially dependent. Most common chronic illness was arthritis (73.3%) and visual problem (58.8%).Conclusions: Our study reveals majority of the elderly women are suffering from one or multiple chronic illnesses. As a matter of fact, there is an urgent need to develop better health care services for the elderly women residing in rural areas.


2021 ◽  
pp. 004947552110448
Author(s):  
Subramani Jagadeesan ◽  
Subramanian Muthathal ◽  
Archismita Santra

In India, the world's second most populous state, an increasing proportion of its population are elderly. Older people invariably face special psychiatric challenges. In a community-based cross-sectional study, depression was found to be present in almost a third of the elderly; furthermore, low family income, poor literacy and uncertain employment status were found to be significant associations.


2021 ◽  
Vol 59 (243) ◽  
pp. 1116-1119
Author(s):  
Aashish Bhattarai ◽  
Anna Acharya ◽  
Krishna Raj Khanal

Introduction: Non-steroidal anti-inflammatory drugs are major drugs in treatment of pain and inflammation of different orthopedic conditions. There are different classes of non-steroidal anti-Inflammatory Drugs based on their selectivity to cyclooxygenase enzyme which has significant differences in safety profile. This study aims to determine the prevalence of non-steroidal anti-inflammatory drugs prescription in the orthopaedic outpatient department of a tertiary care hospital. Methods: This was a descriptive cross-sectional study conducted among the patients in the orthopedic outpatient department of tertiary care hospital from December 2020 to March 2021. Ethical approval was taken from the Institutional Review Committee of the college (Ref: 0311202007). Convenient sampling was done. A structured proforma was used with consent. The data were analyzed with Social Statistical Package for the Social Sciences version 20. Point estimate at 95% Confidence Interval was done and frequency and percentage were calculated. Results: Out of 140 orthopaedic out patient department prescriptions screened, 118 (84.28%) (78.25-90.30 at 95% Confidence Interval) prescriptions included non-steroidal anti-inflammatory drugs. Aceclofenac 76 (64.4%) was the most prescribed non-steroidal anti-inflammatory drug. Conclusions: Aceclofenac was the most preferred agent for the treatment in the department of orthopedics. The most common proton pump inhibitor used alone with non-steroidal anti-inflammatory drugs was rabeprazole.


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