The association between retrospective outcome evaluations and pre-post-treatment changes in psychodynamic group-psychotherapy

2008 ◽  
Vol 49 (4) ◽  
pp. 339-343 ◽  
Author(s):  
HANS HENRIK JENSEN ◽  
ERIK LYKKE MORTENSEN ◽  
MARTIN LOTZ
2015 ◽  
Vol 32 (3) ◽  
pp. 202-208 ◽  
Author(s):  
Paul R. Martin ◽  
Moira Callan ◽  
Archana Kaur ◽  
Karen Gregg

The traditional approach to headache trigger management is to advise avoidance of all triggers, but we have advocated an alternative approach called ‘Learning to Cope with Triggers’ (LCT), in which the objective is to desensitise headache sufferers to some triggers or to build up tolerance for the triggers, using exposure techniques. A recent publication established the efficacy of this approach to trigger management. Reported here are three cases to illustrate how LCT is used in practice. Two cases were male and one was female, with ages ranging from 32 to 67 years. The headache diagnoses were frequent episodic tension-type headache, migraine without aura, and chronic tension-type headache; all had had headaches since childhood/adolescence. The headache triggers that were the focus of the intervention were heat, tiredness, and stress/anger. Post-treatment, changes in the capacity of the triggers to elicit headaches were reported in all three cases. Reductions in headaches from pre- to post-treatment, and from pre- to 4-month follow-up, were: case 1, 69% and 60% respectively; case 2, 76% and 80% respectively; and case 3, 73% and 61% respectively. Decreases in medication consumption, and enhanced self-efficacy were also recorded.


Author(s):  
W. Kinnaird ◽  
A. Stewart-Lord

Abstract Aim: Sexual dysfunction is a common side effect of external beam radiotherapy (EBRT) and androgen deprivation therapy (ADT) to treat prostate cancer. Men are likely to experience erectile dysfunction, low libido, ejaculatory problems and penile shortening. This qualitative study explored men’s perceptions of sexual dysfunction, including factors such as self-perception, relationships and information and support needs. Methods: Semi-structured interviews were carried out with n = 8 men living 18–30 months after EBRT ± ADT. The interviews were transcribed and thematic analysis was carried out. Results: All men experienced sexual dysfunction following treatment. The main themes arising were: (i) priorities—sexual issues were not a priority when making treatment decisions, (ii) information and support—men described a lack of information and support about sexual dysfunction and (iii) impact—sexual dysfunction impacted on their self-perception and relationships. Findings: Men undergoing EBRT/ADT for prostate cancer may be affected by post-treatment changes in sexual function in a range of ways. This study suggests that they would benefit from early and wide-ranging information and support on sexual dysfunction, even if they do not consider it as a priority. Candid discussions about self-perception and relationships, as well as physical changes, may equip them to cope with post-treatment changes.


Medicina ◽  
2020 ◽  
Vol 56 (4) ◽  
pp. 192
Author(s):  
Henrikas Pauzas ◽  
Ugne Gyvyte ◽  
Tadas Latkauskas ◽  
Laura Kairevice ◽  
Paulius Lizdenis ◽  
...  

Background and objectives: The effectiveness of neoadjuvant therapy, which is commonly used for stage II-III rectal cancer (RC) treatment, is limited. Genes associated with the pathogenesis of RC could determine response to this treatment. Therefore, the aim of this study was to investigate the potential predictive value of VEGFA, COX2, HUR and CUGBP2 genes and the associations between post-treatment changes in gene expression and the efficacy of neoadjuvant therapy. Materials and Methods: Biopsies from RC and healthy rectal tissue of 28 RC patients were collected before neoadjuvant therapy and 6-8 weeks after neoadjuvant therapy. The expression levels of VEGFA, COX2, HUR, CUGBP2 genes were evaluated using a quantitative real-time polymerase chain reaction. Results: The results reveal a significantly higher expression of VEGFA, COX2 and HUR mRNA in RC tissue compared to healthy rectal tissue (p < 0.05), and elevated VEGFA gene expression in pre-treatment tissues was associated with a better response to neoadjuvant therapy based on T-stage downstaging (p < 0.05). The expression of VEGFA, HUR and CUGBP2 genes significantly decreased after neoadjuvant therapy (p < 0.05). Responders to treatment demonstrated a significantly stronger decrease of VEGFA and COX2 expression after neoadjuvant therapy than non-responders (p < 0.05). Conclusions: The findings of this study suggest that the pre-treatment VEGFA gene expression might have predictive value for the response to neoadjuvant therapy, while the post-treatment decrease in VEGFA and COX2 gene expression could indicate the effectiveness of neoadjuvant therapy in RC patients.


Author(s):  
Michael Wolf ◽  
U. Schulte ◽  
K. Küpper ◽  
C. Bourauel ◽  
L. Keilig ◽  
...  

Author(s):  
Mohammad Shamim Al Mamun ◽  
Md Zakir Hossain

This case report will evaluate the management of bimaxillary protrusion by standard edge wise technique with extraction of premolars. The objective of treatment was to use mild forces and to provide maximum space for the retraction of anterior teeth. The goal of the treatment was to improve facial appearance. The case was successfully managed by extraction of all first Premolars and fixed appliance therapy using standard edge wise mechanics. Post-treatment changes were good and stableBan J Orthod & Dentofac Orthop, April 2013; Vol-3, No.2


2021 ◽  
Vol 14 (1) ◽  
pp. 3-7
Author(s):  
Umesh Parajuli ◽  
Manish Bajracharya ◽  
Manju Pandey ◽  
Ima Gurung ◽  
Sapna Laxmi Tuladhar

Background: The orthodontic treatment should aim to maintain the inter-canine and inter-molar width to that of the pre-treatment values. The study was conducted with objective to evaluate arch width changes in Class I and Class II patients treated with fixed orthodontics. Methods: This was a hospital-based cross-sectional study with two study groups. The first group included patients with Class I malocclusion, treated with four first premolar extractions and the second group included patients with Class II Div 1 malocclusion, treated with upper two first premolar extractions. The inter-canine and inter-molar width of the pre and post-treatment study model were measured. To compare the changes observed amongst two groups, independent samples t-test was performed. A paired sample t-test was used to evaluate the treatment changes within each group. Results: There was significant increase in inter-canine width in both maxillary and mandibular arches in both the groups. In Class I extraction group there was significant decrease in the inter-molar width in both maxillary and mandibular arches. The Class II Div1 maxillary extraction group also showed significant increase in inter-canine width in both maxillary and mandibular arches. In the same group there was decrease in post treatment Methods: This was a hospital-based cross-sectional study with two study groups. The first group included patients with Class I malocclusion, treated with four first premolar extractions and the second group included patients with Class II Div 1 malocclusion, treated with upper two first premolar extractions. The inter-canine and inter-molar width of the pre and post-treatment study model were measured. To compare the changes observed amongst two groups, independent samples t-test was performed.  A paired sample t-test was used to evaluate the treatment changes within each group. Results: There was significant increase in inter-canine width in both maxillary and mandibular arches in both the groups. In Class I extraction group there was significant decrease in the inter-molar width in both maxillary and mandibular arches. The Class II Div1 maxillary extraction group also showed significant increase in inter-canine width in both maxillary and mandibular arches. In the same group there was decrease in post-treatment inter-molar width in both arches with significant decrease in the maxillary inter-molar width. Conclusion: There was increase in inter-canine width in both Class I extraction group and Class II Div 1 maxillary extraction group with decrease in inter-molar width in both the groups.  


2020 ◽  
Author(s):  
Sam Sedaghat ◽  
Frederick Schmitz ◽  
Johannes Berek ◽  
Charlotte Borchers ◽  
Maya Sedaghat

Abstract Background: To assess the configuration of primary and recurrent synovial sarcoma on MRI. Additionally, to evaluate postoperative MRI regarding diagnostic performance and locoregional post-treatment changes.Methods: Twenty-five patients with histologically proven synovial sarcomas underwent 1.5-T MRI follow-up between 2012 and 2018. In all, 258 pre- and postoperative MRIs with available radiological and pathological were screened for primary/recurrent synovial sarcoma, diagnostic performance (false-positive/-negative and true-positive/-negative values) and post-treatment changes.Results: The median age of the patients was 40±15.2 years. The median volumes of primary and recurrent synovial sarcomas were 603 cm3 and 806 cm3, respectively. Of the patients 24% presented recurrences (n=6). In two patients false-positive diagnosis was made . There was one false-negative diagnosis of synovial sarcoma. Primary synovial sarcomas were significantly most often polycyclic/multilobulated (p=0.01) and heterogeneous in appearance with marked contrast enhancement. Recurrent synovial sarcomas showed two appearances: ovoid/nodular/homogeneous and polycyclic/multilobulated/heterogeneous, both with marked contrast enhancement. The most common post-treatment changes were subcutaneous (92%; p<0.001) and muscular edema (72%; p<0.001-0.003). Conclusion: While the configuration of primary synovial sarcomas was mainly polycyclic/multilobulated/heterogeneous, recurrent synovial sarcomas showed two shapes: ovoid/homogeneous and polycyclic/multilobulated/heterogeneous. MRI is still a highly valuable imaging modality for the postoperative surveillance of synovial sarcomas. Subcutaneous and muscular edema are common post-treatment changes.


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