Methylprednisolone therapy for short-term prevention of SUNCT syndrome

Cephalalgia ◽  
2009 ◽  
Vol 30 (6) ◽  
pp. 735-739 ◽  
Author(s):  
A Trauninger ◽  
B Alkonyi ◽  
N Kovács ◽  
S Komoly ◽  
Z Pfund
Keyword(s):  
Physical Disability ◽  
Conjunctival Injection ◽  
Short Term ◽  
Sunct Syndrome ◽  
Abortive Treatment ◽  
Anti Inflammatory ◽  
Daily Pain

Short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) is characterized by severe and frequent daily pain attacks causing transient physical disability for the patients during the headache period. Currently there is no option for abortive treatment of the attacks, mainly due to the short-lived nature and frequency of the repeated headaches, while highly efficacious therapy is also unavailable for short-term prevention. We report rapidly suppressed headache attacks with orally administered methylprednisolone in eight headache periods of three patients with idiopathic, episodic SUNCT syndrome. The remission was maintained until the period was over in all cases. Although the mechanism of methylprednisolone action is unclear, it is probably based on the anti-inflammatory effects of the drug.

scholarly journals SUNCT syndrome associated with pituitary tumor: case report

2006 ◽  
Vol 64 (2b) ◽  
pp. 507-510 ◽  
Author(s):  
Pedro A.S. Rocha Filho ◽  
Antonio Cezar R. Galvão ◽  
Manoel J. Teixeira ◽  
Getulio D. Rabello ◽  
Ida Fortini ◽  
...  
Keyword(s):  
Case Report ◽  
Clinical Condition ◽  
Pituitary Tumor ◽  
Complete Removal ◽  
Pathological Diagnosis ◽  
Conjunctival Injection ◽  
Intense Pain ◽  
Sunct Syndrome ◽  
The Subject ◽  
Daily Pain

For twelve years, the subject of this report, a 38-year-old man, presented a clinical condition compatible with the SUNCT (short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing) syndrome. He presented a stabbing and intense daily pain located in the left pre-auricular and temporal regions. Each of these intense pain attacks lasted around one minute and presented a frequency of two to eight times per day. The pain was associated with ipsilateral lacrimation, conjunctival injection and rhinorrhea. MRI revealed a pituitary tumor with little suprasellar extent. The subject’s serial assays of prolactin, GH, TSH and ACTH were within normal levels. Following transsphenoidal hypophysectomy, with complete removal of the tumor, the subject no more presented pain. The pathological diagnosis was non-secreting adenoma. Fourteen months after the surgery, he remains symptom-free.

Nonsteroidal anti-inflammatory drug use does not affect short-term endoscopic and histologic outcomes afterHelicobacter pylorieradication in patients with rheumatoid arthritis

2007 ◽  
Vol 17 (3) ◽  
pp. 228-234 ◽  
Author(s):  
Eiichi Tanaka ◽  
Shigeo Kamitsuji ◽  
Eisuke Inoue ◽  
Toru Yamada ◽  
Ayako Nakajima ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Drug Use ◽  
Short Term ◽  
Inflammatory Drug ◽  
Anti Inflammatory

Short-lasting, unilateral neuralgiform headache attacks with conjunctival injection and tearing syndrome treated successfully with transsphenoidal resection of a growth hormone-secreting pituitary adenoma

2008 ◽  
Vol 109 (1) ◽  
pp. 123-125 ◽  
Author(s):  
Matthew A. Adamo ◽  
Doniel Drazin ◽  
A. John Popp
Keyword(s):  
Growth Hormone ◽  
Pituitary Adenoma ◽  
Tumor Resection ◽  
Conjunctival Injection ◽  
Sunct Syndrome ◽  
Trigeminal Autonomic Cephalgias ◽  
Transsphenoidal Resection

Short-lasting, unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) syndrome was first described in 1978 as one of the trigeminal autonomic cephalgias. In this paper the authors present a patient with a growth hormone–secreting pituitary adenoma who experienced resolution of SUNCT syndrome after transsphenoidal tumor resection.

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