Leaf tissue of broccoli (Brassica oleracea L. ssp. italica Plenck. cv. Waltham 29) and Brussels sprouts (B. oleracea ssp. gemmifera cv. Jade Cross) was collected at three times during the growing season from plants fertilized with four levels of N, P, and K in factorial combination with, and without, farmyard manure. The leaf tissue was analyzed for total N, P, and K concentration. Leaf-tissue N, P, and K increased with increasing levels of applied N, P, and K, respectively. Significant N × P interactions occurred in which applied N increased tissue-P levels and applied P increased tissue-N levels. Growth responses to applied N and P tended to reduce tissue-K levels. Manure had almost no effect on tissue N and only small effects on tissue P and K. Concentrations of all three nutrients declined during the growing season. Critical N, P, and K levels for plant growth were within previously published ranges of 5.2–6.0% N, 0.35–0.60% P, and 1.7–2.2% K.