Evaluation of a New Immunoassay for Determination of Phenytoin and Phenobarbital: Results of a European Collaborative Control Study

Epilepsia ◽  
1977 ◽  
Vol 18 (3) ◽  
pp. 367-374 ◽  
Author(s):  
D. Schmidt ◽  
V. Goldberg ◽  
P. J. M. Guelen ◽  
S. Johannessen ◽  
E. v. d. Kleijn ◽  
...  
Keyword(s):  
Collaborative Control ◽  
Control Study

scholarly journals Factores de riesgo del síndrome confusional agudo en ancianos hospitalizados.

2018 ◽  
Author(s):  
Juan Rodado ◽  
Irine Aragon
Keyword(s):  
Risk Factors ◽  
Previous History ◽  
Source Population ◽  
Co Morbidity ◽  
Factores De Riesgo ◽  
History Of ◽  
Transversal Study ◽  
Special Relevance ◽  
Control Study

Background: Acute confusional syndrome is a current problem of special relevance among elderlypatients admitted to hospital medical services. The determination of its risk factors is an essential process in the development and implementation of programs to prevent this complication. Methods: With the mentioned aim we have carried out this case-control study as an analytical, observational, retrospective and transversal study, whose source population was integrated by 60 patients over age 65 according to inclusion and exclusion criteria and divided into two groups: with and without delirium. Discussion: Our analysis has confirmed the association between these factors and delirium: illness severity; previous history of Delirium (OR 10.6); mental status (OR 7.3); high risk medications (OR 6.9); renal failure (OR 6.5); medication at risk added (OR 6); physical status (OR 5.2); use of neuroleptics (OR5.1); anemia (OR 4.75); sodium alterations (OR 4.5); urinary catheter (OR 3.8); low albumin (OR 3.7); infection (OR 3.1). Conclusion: There is no relationship proved between acute confusional syndrom and the following factors: use of benzodiazepines, aggressive procedures, immobility, old age, dementia, diminished ADL skills, co-morbidity and polypharmacy, even if they have been identified as risk factors in previous studies. Hence, these results should be interpreted with caution.

An intact bony tympanic facial canal does not protect from secondary facial paresis in adult acute otitis media

2020 ◽  
Vol 134 (5) ◽  
pp. 409-414
Author(s):  
C Meerwein ◽  
S Pazahr ◽  
T M Stadler ◽  
N Nierobisch ◽  
A Dalbert ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Otitis Media ◽  
Case Control Study ◽  
Acute Otitis Media ◽  
Case Control ◽  
Facial Canal ◽  
Facial Paresis ◽  
Retrospective Case ◽  
Control Study

AbstractObjectiveTo investigate the prevalence of bony dehiscence in the tympanic facial canal in patients with acute otitis media with facial paresis compared to those without facial paresis.MethodA retrospective case–control study was conducted on acute otitis media patients with facial paresis undergoing high-resolution temporal bone computed tomography.ResultsForty-eight patients were included (24 per group). Definitive determination of the presence of a bony dehiscence was possible in 44 out of 48 patients (91.7 per cent). Prevalence of bony dehiscence in acute otitis media patients with facial paresis was not different from that in acute otitis media patients without facial paresis (p = 0.21). Presence of a bony dehiscence was associated with a positive predictive value of 66.7 per cent in regard to development of facial paresis. However, an intact bony tympanic facial canal did not prevent facial paresis in 44.8 per cent of cases (95 per cent confidence interval = 34.6–55.6).ConclusionPrevalence of bony dehiscence in acute otitis media patients with facial paresis did not differ from that in acute otitis media patients without facial paresis. An intact tympanic bony facial canal does not protect from facial paresis development.

Coagulation Parameters among Women with Obstetric Complications in Specialist Hospital Sokoto, Nigeria

2020 ◽  
pp. 23-33
Author(s):  
Onuigwe Festus Uchechukwu ◽  
Khadija Bello Tudu ◽  
Erhabor Osaro ◽  
Buhari Hauwa Ali ◽  
Bagudo Aliyu Ibrahim ◽  
...  
Keyword(s):  
Platelet Count ◽  
Pregnant Women ◽  
Case Control Study ◽  
Obstetric Complications ◽  
Age Group ◽  
Obstetrics And Gynaecology ◽  
Counting Chamber ◽  
Manual Methods ◽  
Control Study

Background and Aim: Obstetric complications are part of the leading causes of maternal mortality worldwide. This study was carried out to investigate the effect of   complications on the Prothrombin time (PT), activated partial thromboplastin time (APTT), and platelet count (PLC). Women with obstetric complications were recruited as subjects). Pregnant women without complications were included as controls. Study Design: This is a case-control study. Place and Duration of Study: The study took place in Obstetrics and Gynaecology Department of Specialist Hospital Sokoto and the duration was six months. Methodology: Pregnant women aged 18–41 years (mean age 29.5 years) were recruited for the study. The determination of PT and APTT was done by manual methods using commercially prepared Agappe reagent kits, whereas PLC was done by manual methods using a haemocytometer (Improved Neubauer counting chamber). Data were analyzed using SPSS version 23. Results: The results of PT and APTT were significantly higher among women with obstetric complications (14.26±0.23 seconds and 31.32±0.70 second) compared to normal pregnant women (13.00 ± 0.13 seconds and 29.66±0.33) (P<0.05). The PLC was significantly lower among women with obstetric complications compared to women without obstetric complications (P< 0.05).Obstetric complications in subject show a significant association when compared with PT and APTT (P< 0.05). The age group of subjects shows a significant association when compared with APTT (P< 0.05). Conclusion: Findings from this study have shown that obstetric complications causes decrease in platelet count and prolongation in PT and APTT. There is need to assess the PT, APTT and Platelet count routinely for pregnant women to improve the ante-natal care in Specialist Hospital Sokoto.

Determination of the Correlation between Dermatoglyphics and Periodontitis: A Case Control Study

2020 ◽  
Vol 34 (1) ◽  
pp. 23-29
Author(s):  
Jose Paul ◽  
Johnson Prakash d�Lima ◽  
Aswathy Sheela Sudhakar ◽  
Senny Thomas Parackal ◽  
Binitta Paul K ◽  
...  
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Control Study

Isolated itching of external auditory canal: clinicopathological study with immunohistochemical determination of antimicrobial peptides

2010 ◽  
Vol 125 (3) ◽  
pp. 227-230 ◽  
Author(s):  
B Acar ◽  
G Güler Simsek ◽  
S Oguztuzun ◽  
M Zaim ◽  
R Murat Karasen
Keyword(s):  
Antimicrobial Peptides ◽  
External Auditory Canal ◽  
Case Control Study ◽  
Case Control ◽  
Biopsy Specimens ◽  
Significant Difference ◽  
Skin Biopsies ◽  
Control Study ◽  
Prospective Case Control Study

AbstractObjective:This study aimed to demonstrate the histological and immunohistological features of skin biopsy specimens from patients complaining of isolated itching of the external auditory canal.Materials and methods:A prospective, case–control study was performed of 24 patients undergoing evaluation for contact dermatitis of the external auditory canal, and 24 controls. Skin biopsies were examined histologically by a single, blinded dermatopathologist, using light microscopy, to determine histopathological characteristics. The immunohistological presence of the antimicrobial peptides human β-defensin-3 and LL-37 cathelicidin was also assessed. Findings for patients and controls were compared.Results:There was a statistically significant difference in the degree of inflammation, comparing patients and controls (p < 0.05). There was no significant difference in the presence of spongiotic changes, comparing patients and controls (p > 0.05). Furthermore, the patients' skin biopsies did not show pronounced expression of human β-defensin-3 or LL-37 cathelicidin.Conclusion:Histological and immunohistological examination of skin biopsies from cases of isolated itching of the external auditory canal did not support a diagnosis of dermatitis.

Sign in / Sign up

Export Citation Format

Share Document