Plasminogen gene expression is regulated by nerve growth factor

2007 ◽  
Vol 5 (8) ◽  
pp. 1715-1725 ◽  
Author(s):  
A. GUTIÉRREZ-FERNÁNDEZ ◽  
R. J. PARMER ◽  
L. A. MILES
Keyword(s):  
Gene Expression ◽  
Nerve Growth Factor ◽  
Growth Factor ◽  
Nerve Growth

scholarly journals Seasonal Expression of NGF and Its Cognate Receptors in the Ovaries of Grey Squirrels (Sciurus carolinensis)

Animals ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 1558
Author(s):  
Margherita Maranesi ◽  
Francesco Alessandro Palermo ◽  
Antonello Bufalari ◽  
Francesca Mercati ◽  
Daniele Paoloni ◽  
...  
Keyword(s):  
Gene Expression ◽  
Nerve Growth Factor ◽  
Growth Factor ◽  
Breeding Season ◽  
Granulosa Cells ◽  
Reproductive Physiology ◽  
Tyrosine Kinase Receptor ◽  
Grey Squirrel ◽  
Nerve Growth ◽  
Grey Squirrels

The grey squirrel is an invasive alien species that seriously threatens the conservation of the native red squirrel species. With the aim of characterizing the reproductive physiology of this species due to its great reproductive success, the function of the ovarian nerve growth factor (NGF) system was analyzed in a grey squirrel population living in central Italy. During the breeding and nonbreeding seasons, the ovarian presence, distribution, and gene expression of NGF, neurotrophic tyrosine kinase receptor 1 (NTRK1), and nerve growth factor receptor (NGFR), as well as NGF plasma concentrations, were evaluated in female grey squirrels. NGF was found in the luteal cells and in the thecal and granulosa cells of follicles, while NTRK1 and NGFR were only observed in follicular thecal and granulosa cells. NGF and NGFR transcripts were almost two-fold greater during the breeding season, while no seasonal differences were observed in NTRK1 gene expression. During the breeding season, NGFR was more expressed than NTRK1. Moreover, no changes were observed in NGF plasma levels during the reproductive cycle. The NGF system seems to be involved in regulating the ovarian cycle mainly via local modulation of NGF/NGFR, thus playing a role in the reproductive physiology of this grey squirrel population.

scholarly journals Overexpression of HuD, but Not of Its Truncated Form HuD I+II, Promotes GAP-43 Gene Expression and Neurite Outgrowth in PC12 Cells in the Absence of Nerve Growth Factor

2002 ◽  
Vol 75 (3) ◽  
pp. 1103-1114 ◽  
Author(s):  
Kim D. Anderson ◽  
Melissa A. Morin ◽  
Andrea Beckel-Mitchener ◽  
Charlotte D. Mobarak ◽  
Rachael L. Neve ◽  
...  
Keyword(s):  
Gene Expression ◽  
Nerve Growth Factor ◽  
Growth Factor ◽  
Neurite Outgrowth ◽  
Pc12 Cells ◽  
Truncated Form ◽  
Nerve Growth
Sign in / Sign up

Export Citation Format

Share Document