Intima-Media Thickness is Associated With Non-Traditional Risk Factors and Ischemic Heart Disease in Hemodialysis Patients

2011 ◽  
Vol 16 (1) ◽  
pp. 104-106 ◽  
Author(s):  
Cleto Álvarez-Aguilar ◽  
Daniel Lara-Romero ◽  
Javier Piñón-Escobedo ◽  
Anel Gómez-García ◽  
Alfonso R Álvarez-Paredes
Keyword(s):  
Risk Factors ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Intima Media Thickness ◽  
Hemodialysis Patients ◽  
Ischemic Heart ◽  
Media Thickness ◽  
Traditional Risk Factors

scholarly journals Correlation of Coronary Angiographic Severity with Carotid intima Media Thickness and Flow mediated dilatation of brachial Artery in Patients with Ischemic Heart Disease

2013 ◽  
Vol 5 (2) ◽  
pp. 165-172
Author(s):  
SME Mahabub ◽  
AEMM Islam ◽  
KMN Sabah ◽  
AW Chowdhury ◽  
M Ghiasuddin ◽  
...  
Keyword(s):  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Brachial Artery ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Ischemic Heart ◽  
Media Thickness ◽  
Flow Mediated Dilatation ◽  
Extent Score ◽  
Vessel Score

Background: Ischemic Heart Disease which encompasses Acute Coronary Syndrome and Chronic Stable Angina is the most common cause of worldwide mortality and morbidity. Carotid intima media thickness (CIMT) is a non-invasive ultrasonographic technique to image the carotid arteries which measures the thickness of the intima and media of these vessels. It is a marker of atherosclerotic process. Flow mediated dilatation (FMD) is a marker of endothelial function of arteries. Ischemic heart disease can be predicted long before its actual occurrence by observing these two phenomenons. Methods: This cross sectional study done in the Department of Cardiology, Dhaka Medical College Hospital during the period of Oct 2010- Sept 2011.We enrolled 102 patients admitted with IHD by purposive sampling. We assessed FMD of brachial artery, CIMT by vascular duplex. Coronary artery disease severity was assessed by vessel score, stenosis score and extent score from angiography. Results:The mean (±SD) age of the patients was 50.9(±11.3) years. The male- female ratio was 5:1. CIMT has significant negative correlation with FMD (r=-.407, p=<.001). Flow mediated dilatation of brachial artery has weak but significant negative co-relation with vessel score(r=-.609, p=<.001), stenosis score(r=- .493, p=<.001) and extent score (r=-.477, p=<.001). However, carotid intima media thickness has weak but positive correlation with vessel score (r=.447, p=<.001), stenosis score (r=.417, p=<.001) and extent score(r=.412, p=<.001). Conclusion: The present study concludes CIMT has significant negative correlation with flow mediated dilatation of brachial artery. FMD has weak but significant negative co-relation and CIMT has weak but positive correlation with vessel score, stenosis score and extent score of coronary arteries. DOI: http://dx.doi.org/10.3329/cardio.v5i2.14321 Cardiovasc. j. 2013; 5(2): 165-172

scholarly journals A study of lipid profile and carotid artery and abdominal aorta intima-media thickness in children with parental history of premature ischemic heart disease

2018 ◽  
Vol 5 (3) ◽  
pp. 1013 ◽  
Author(s):  
Puneeth K. Pai ◽  
Nagendra K. ◽  
Savitha Mysore Ramaraj
Keyword(s):  
Heart Disease ◽  
Carotid Artery ◽  
Ischemic Heart Disease ◽  
Abdominal Aorta ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Ischemic Heart ◽  
Parental History ◽  
Media Thickness ◽  
History Of

Background: Children born to parents with ischemic heart disease (IHD) can have dyslipidemia, a marker for IHD, detectable in early childhood and track to adulthood. Dyslipidemia along with factors like BMI, diet, sedentary activity increases risk of child developing IHD in adulthood. Early detection with non-invasive methods such as B mode ultrasound to measure carotid artery and abdominal aorta intima-media thickness can help in modification of these risk factors by suitable interventional strategies. The objectives of this study was to study the lipid profile and carotid artery and abdominal aorta intima-media thickness among children in the age group 5-18 years born to parents with history of premature IHD.Methods: 23 children of parents with premature IHD and aged matched 28 controls without any family history of IHD were analyzed for cardiovascular risk factors: lipid profile and carotid and abdominal aorta intima-media thickness. The carotid intima-media thickness and abdominal aorta intima-media thickness was found by using B mode ultrasound.Results: Mean abdominal aorta intima-media thickness was significantly higher among children with parental history of premature IHD than in those without it. Abdominal aorta intima-media thickness also showed significant positive correlation with total cholesterol. Carotid intima-media thickness showed positive correlation with the waist circumference. Mean total cholesterol levels (TC), low density lipoprotein cholesterol (LDL) and triglycerides (TG) were higher in children with family history as compared to children without family history but it was not statistically significant.Conclusions: Abdominal aortic IMT is significantly more among children with parental history of premature ischemic heart disease compared to children without parental history of premature ischemic heart disease. Abdominal aortic intima-media thickness has significant association with total cholesterol while carotid intima-media thickness is significantly associated with waist circumference.

scholarly journals Correlations Between Femoral Intima-media Thickness and Cardiovascular Risk Factors in Patients with Ischemic Heart Disease

2016 ◽  
Vol 1 (1) ◽  
pp. 32-36
Author(s):  
Zsuzsanna Jeremiás ◽  
Katalin Makó ◽  
Norbert Szekeres ◽  
Emese Rapolti ◽  
Imre Benedek ◽  
...  
Keyword(s):  
Heart Disease ◽  
Cardiovascular Risk ◽  
Ischemic Heart Disease ◽  
Intima Media Thickness ◽  
Left Ventricular ◽  
Ischemic Heart ◽  
Peripheral Vascular ◽  
Posterior Tibial ◽  
Media Thickness ◽  
The Mean

Abstract Background: Atherosclerosis has a systemic impact, producing gradual stenoses of the main vessels, and many imaging techniques have been developed in order to detect and quantify the atherosclerotic lesions. Peripheral artery disease has been shown to be associated with the presence of coronary heart disease, at the same time with carotid artery involvement. The utility of the carotid artery intima-media thickness (IMT) in predicting cardiovascular events caused by atherosclerosis, led to the idea that assessing the femoral artery IMT could have a similar impact. Study aim: We sought to determine the correlations between the femoral IMT, the degree of left ventricular systolic dysfunction and cardiovascular risk factors in patients with established diagnosis of ischemic heart disease. Material and methods: We prospectively included 27 patients with diagnosed ischemic heart disease. The ankle-brachial index (ABI) was assessed for the anterior and posterior tibial arteries. The left ventricular ejection fraction (LVEF) was determined by echocardiography. The femoral IMT was measured by peripheral vascular ultrasound, at the common femoral artery, 1 cm proximally from the bifurcation. The patients were divided into 2 groups: Group 1 – patients with IMT<0.9mm, and Group 2: patients with IMT >0.9 mm. Results: The mean age of the study population was 65.52 ± 11.44 years, and 77.77% were males. The mean glycemia levels were 99.89 ± 30.34 mg/dl, total cholesterol: 176.81 ± 43.09 mg/dl and the mean triglyceride level 140 ± 65.12mg/dl. The mean LEVF was 49.98% ± 12.73%, and femoral IMT 0.75 mm ± 0.25 mm. IMT significantly correlated with cholesterol levels (R = 0.383, p = 0.048), anterior and posterior tibial artery pressures (R = 0.450, p = 0.018, R = 0.418, p = 0.029 respectively) and ABI (R = 0.623, p = 0.005). There was no significant correlation between the LVEF and the IMT (R = −0.143, p = 0.475). There was a significant difference between the 2 groups regarding the minimum anterior tibial artery pressure (95.57 mmHg vs. 63.5 mmHg, p = 0.0011) and the minimum ABI (0.85 vs. 0.5, p = 0.015), and the femoral IMT (p = 0.0001). For patients with a femoral IMT >0.9 mm, a significant correlation was found between ABI and femoral IMT (R = −0.710, p <0.0001). Conclusion: The femoral intima-media thickness, assessed with peripheral vascular ultrasound, could be a new marker in evaluating the global cardiovascular risk in patients with ischemic heart disease. Femoral IMT could become a new marker for systemic atherosclerosis.

A STUDY OF RHEUMATOID FACTOR AND ITS RELATION TO ISCHEMIC HEART DISEASE

2021 ◽  
pp. 91-93
Author(s):  
M. Ajith Kumar ◽  
Nikitha Shirine Todeti
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Rheumatoid Factor ◽  
Traditional Risk Factor ◽  
Ischemic Heart ◽  
Special Role ◽  
Cross Sectional ◽  
Traditional Risk Factors

INTRODUCTION : Ischemic heart disease (IHD) is a leading cause of death in the world. Most of the subjects with IHD may have traditional risk factors including diabetes,smoking, hypertension,obesity. Rheumatoid Factor (RF) has been associated with an increased likelihood of developing IHD.Presence of RF in general population may identify the subjects with a similar immune pathology to patients with RA, who may also share an increased likelihood of developing IHD and that RF may have special role in the pathogenisis of IHD . MATERIALS AND METHODS: Cross sectional observational study done from September 2020 to August 2021 in Kamineni institute of medical sciences Narketpally, included 100 patients, who were all RF positive.During the study period they were evaluated for IHD by E CG and ECHO.Those who are included in the study were evaluated for traditional risk factors h/o Diabetes, smoking,family h/o IHD and hypertension,BMI for Obesity and features of RA. A resting 12 lead ECG was carried out for features of IHD.The following ch anges in the ECG were taken as marker of ischemia: 1)The combination of ST elevation in a set of leads and reciprocal ST depression in a set of leads.2) Inversion of T with ST still being elevated.3) Presence of pathological Q waves RESULTS : Of the 100 patients with RF positivity, there were 65 females and 35 males. Ischemic changes in ECG in presence of RF with traditional risk factor is n=12 (75%) M 8(50%) F-- 4(25%) and RF without traditional risk factor is n=4 (25%) M-4(25%) F-0.In the present study there were 16 patients who had RF positivity with Ischemic changes in ECG. 12 were males and 4 were females. CONCLUSIONS: RF per se can be considered as one of the risk factor for Ischemic heart disease in males. Ÿ RF associated with traditional risk factors increase the prevalence of IHD. Ÿ Though more female patients have positive RF, they are not vulnerable to IHD.

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