Convergent Validity of Suffering and Quality of Life as measured by The Hidradenitis Suppurativa Quality of Life

Background: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease with adverse physical and psychosocial impacts. The development of an HS quality-of-life measure, HS-QoL, has been recently described. Objective: This study was designed to validate the HS-QoL. Method: Fifty-five patients with HS from 4 dermatology clinics completed the 30-minute online survey. Item reduction, reliability (internal consistency), and correlation analysis (to assess convergent validity) were conducted. Results: The HS-QoL was reduced from 53 items to 44 items, resulting in a 7-subscale questionnaire. All subscales demonstrated excellent internal consistency, except for the support subscale, which had adequate internal consistency. All 7 HS-QoL subscales were related to other measures of QoL, life satisfaction, and mental health, which demonstrates convergent validity. Conclusion: The 44-item HS-QoL demonstrated strong preliminary evidence of reliability (internal consistency) and convergent validity.

Download Full-text

Translation and Validation of the Thai Version of the Wisconsin Quality of Life Questionnaire (TH WISQoL) for Kidney Stone Patients

Journal of the Medical Association of Thailand ◽

10.35755/jmedassocthai.2020.11.11450 ◽

2020 ◽

Vol 103 (11) ◽

pp. 1194-1199

Keyword(s):

Quality Of Life ◽

Internal Consistency ◽

Kidney Stone ◽

Convergent Validity ◽

Large Scale ◽

Short Form ◽

Outcome Measurement ◽

Life Questionnaire ◽

Sf 36

Objective: To develop and validate a Thai version of the Wisconsin Quality of Life (TH WISQoL) Questionnaire. Materials and Methods: The authors developed the TH WISQoL Questionnaire based on a standard multi-step process. Subsequently, the authors recruited patients with kidney stone and requested them to complete the TH WISQoL and a validated Thai version of the 36-Item Short Form Survey (TH SF-36). The authors calculated the internal consistency and interdomain correlation of TH WISQoL and compared the convergent validity between the two instruments. Results: Thirty kidney stone patients completed the TH WISQoL and the TH SF-36. The TH WISQoL showed acceptable internal consistency for all domains (Cronbach’s alpha 0.768 to 0.909). Interdomain correlation was high for most domains (r=0.698 to 0.779), except for the correlation between Vitality and Disease domains, which showed a moderate correlation (r=0.575). For convergent validity, TH WISQoL demonstrated a good overall correlation to TH SF-36, (r=0.796, p<0.05). Conclusion: The TH WISQoL is valid and reliable for evaluating the quality of life of Thai patients with kidney stone. A further large-scale multi-center study is warranted to confirm its applicability in Thailand. Keywords: Quality of life, Kidney stone, Validation, Outcome measurement

Download Full-text

Quality of Life in Hidradenitis Suppurativa: An Update

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18116131 ◽

2021 ◽

Vol 18 (11) ◽

pp. 6131

Author(s):

Pavel V. Chernyshov ◽

Andrew Y. Finlay ◽

Lucia Tomas-Aragones ◽

Francoise Poot ◽

Francesca Sampogna ◽

...

Keyword(s):

Quality Of Life ◽

Hidradenitis Suppurativa ◽

Acne Inversa ◽

Health Related Quality ◽

Number Of Patients ◽

Related Quality ◽

Health Related ◽

Positive Effect ◽

Specific Health

Knowledge on hidradenitis suppurativa/acne inversa (HS) is rapidly increasing. HS has a profound impact on patients and their family life. Several factors, such as comorbidities, unemployment and HS severity, make this impact even more severe. The most widely used instrument to measure this impact is the dermatology-specific DLQI. We also identified six HS-specific health-related quality of life (HRQoL) instruments. Of them, HIDRAdisk, HSIA, HiSQOL and HSQoL-24 are better validated but there is still lack of experience of its use. Several treatment methods showed positive effect on patients’ HRQoL. Surgery remains a method with a substantial positive effect on HRQoL. Several studies confirming a positive effect of adalimumab on the HRQoL of patients with HS were published during the last three years. Data on the influence of several other biologics on HRQoL of HS patients are controversial or based on studies with a small number of patients.

Download Full-text

Uncovering burden disparity: A comparative analysis of moderate to severe psoriasis and hidradenitis suppurativa impact on quality-of-life

Journal of the American Academy of Dermatology ◽

10.1016/j.jaad.2016.02.038 ◽

2016 ◽

Vol 74 (5) ◽

pp. AB10

Keyword(s):

Quality Of Life ◽

Comparative Analysis ◽

Hidradenitis Suppurativa ◽

Severe Psoriasis

Download Full-text

Translation and initial validation of the occupational balance questionnaire to Arabic—Occupational Balance Questionnaire-A

British Journal of Occupational Therapy ◽

10.1177/03080226211039432 ◽

2021 ◽

pp. 030802262110394

Author(s):

Brightlin N Dhas ◽

Petra Wagman ◽

Firas A Marji ◽

Carita Håkansson ◽

Ricardo Carrasco

Keyword(s):

Quality Of Life ◽

Internal Consistency ◽

Content Validity ◽

Convergent Validity ◽

Occupational Therapists ◽

Health Indicators ◽

Family Quality Of Life ◽

Cognitive Debriefing ◽

Arabic Speaking

Introduction Occupational balance (OB) is related to many health indicators, including quality of life. The Occupational Balance Questionnaire (OBQ11) was developed to measure OB, and to date, no Arabic translations of the questionnaire exist. The aim of the study was to describe the translation process of OBQ11 to Arabic and to evaluate its content validity, internal consistency, construct validity, and convergent validity. Methods OBQ11 was translated to Arabic (OBQ11-A) following standard guidelines. Content validity feedback was obtained from ten Arabic-speaking occupational therapists and in a cognitive debriefing with seven volunteers. In addition, OBQ11-A and the Family Quality of Life Survey-2006 were administered to 67 Arabic-speaking participants from a larger study about OB among parents. Results High level of agreement was found on the content of OBQ11-A from the occupational therapists. Cognitive debriefing interviews indicated that OBQ11-A was easy to understand. Cronbach’s alpha for the total OBQ11-A score was 0.864 indicating good internal consistency. Exploratory factor analysis showed acceptable factor loadings for all items. The total scores showed positive statistically significant associations with Family Quality of Life Scores ( r = 0.561, p < 0.001). Conclusions OBQ11-A may prove useful for assessing OB in Arabic-speaking populations. Further research is needed to establish its reliability.

Download Full-text

Trends in Hidradenitis Suppurativa Disease Severity and Quality of Life Outcome Measures: A Systematic Review (Preprint)

10.2196/preprints.27869 ◽

2021 ◽

Author(s):

Jalal Maghfour ◽

Torunn Elise Sivesind ◽

Cory A. Dunnick ◽

Robert Paul Dellavalle

Keyword(s):

Quality Of Life ◽

Systematic Review ◽

Disease Severity ◽

Outcome Measures ◽

Hidradenitis Suppurativa ◽

Life Quality ◽

Clinical Score ◽

Validity And Reliability ◽

Patient Reported

BACKGROUND While there has been an increase in the number of randomized, controlled trials (RCTs) evaluating treatment efficacy for HS, instrument measurements of disease severity and quality of life (QoL) are varied, making compilation of data and comparison between studies a challenge for clinicians. OBJECTIVE The aim of this review is to evaluate trends in disease severity scales and patient reported outcome measures used in RCTs assessing treatment interventions among HS patients. METHODS A primary systematic literature review was conducted in August 2020. PubMed/MEDLINE, Embase, Web of Science, and Cochrane databases were used to identify all articles published from January 1964 to July 2020. The study was prospectively registered with PROSPERO (ID: 209582). Twenty-five articles were included in the systematic review. RESULTS Sartorius and modified Sartorius scores (n=8), and Hidradenitis Suppurativa Clinical score (HiSCs) (n=8) were the most commonly used instruments for disease severity. Participants’ pain, followed by Dermatology Life Quality Index (DLQI), were the most common QoL measures used in the reviewed studies. CONCLUSIONS Heterogeneity of data characterizing both the validity and reliability of existing outcome measures hinders interpretation and translation of the results from RCTs into clinical practice. Many of the QoL measures identified were not specific to HS and may not be representative of all factors impacting patients.

Download Full-text

Translation, adaptation and initial validation of Food Allergy Quality of Life Questionnaire: child form in Greek

Health Psychology Research ◽

10.4081/hpr.2016.4624 ◽

2016 ◽

Vol 4 (1) ◽

Cited By ~ 3

Author(s):

Zoe Morou ◽

Georgios N. Lyrakos ◽

Nikolaos G. Papadopoulos ◽

Nikolaos Douladiris ◽

Athina Tatsioni ◽

...

Keyword(s):

Quality Of Life ◽

Factor Analysis ◽

Food Allergy ◽

Convergent Validity ◽

Underlying Structure ◽

Life Questionnaire ◽

Cronbach’S Alpha ◽

Quality Of Life Questionnaire ◽

Cronbach's Alpha

The aim of the study is to determine the reliability and validity of the Greek version of the Food Allergy Quality of life Questionnaire- Child Form (FAQLQ-CF). After linguistic validation, the Greek FAQLQCF, Food Allergy Independent Measure (FAIM) and Pediatric Quality of Life Inventory (PedsQL™) were used by a physician to interview children diagnosed with food allergy and aged 8-12 via telephone. Cronbach’s alpha was used to evaluate reliability, and factor analysis to assess construct validity. The correlation between FAQLQ-CF and FAIM was moderate (rho=0.509, P<0.001) and internal consistency was strong (Cronbach’s alpha 0.905). FAQLQ-CF discriminated well each question’s contribution to children’s quality of life deterioration (32- 80%), each child’s quality of life (17-89%), children differing in doing things with others (total score 3.55 vs 2.57, difference =0.98 > minimal clinical importance difference = 0.5; P<0.001), but not children differing in reporting anaphylaxis. The total FAQLQ-CF score correlated with the total PedsQL™ score and with the score of one of PedsQL™ subscales, demonstrating convergent validity. Factor analysis uncovered an underlying structure of four factors, explaining 50% of the variance. We can conclude that Greek FAQLQ-CF is a reliable, valid, discriminant tool for interviewing food allergic children aged 8- 12, detecting those in need for immediate care.

Download Full-text

Efficacy of adalimumab in moderate to severe hidradenitis suppurativa: Real life data

Dermatology Reports ◽

10.4081/dr.2018.7859 ◽

2018 ◽

Vol 10 (2) ◽

Cited By ~ 8

Author(s):

Aikaterini Kyriakou ◽

Anastasia Trigoni ◽

Nikiforos Galanis ◽

Dimitrios Sotiriadis ◽

Aikaterini Patsatsi

Keyword(s):

Quality Of Life ◽

Hidradenitis Suppurativa ◽

Therapeutic Potential ◽

Therapeutic Option ◽

Real Life ◽

Life Quality ◽

Global Assessment Scale ◽

Friedman's Test ◽

Adalimumab Treatment

Hidradenitis suppurativa (HS) is a relapsing, inflammatory disease characterized by painful nodules, abscesses, sinuses track formation and scarring. HS has a great impact on patients’ quality of life and its treatment may be really challenging. Adalimumab provides a new therapeutic option for HS. Our aim was to assess the therapeutic potential of adalimumab on patients with HS based on the data from the daily clinical practice of an HS Outpatient Clinic. 19 patients with clinically evident moderate to severe HS, under adalimumab treatment for at least 24 week, participated in this observational, retrospective study. The Hidradenitis Suppurativa Physician’s Global Assessment scale, Modified Santorius scale and Dermatology Life Quality Index (DLQI) at baseline, week 4, week 12 and week 24 were retrieved from the records. Both Modified Santorius score and DLQI were significantly decreased during the weeks of evaluation (Friedman’s test; P < 0.001). The proportion of patients who achieved clinical response was 10.5% (n = 2) at week 4, 42.1% (n = 8) at week 12 and 63.2% (n = 12) at week 24. Treatment with adalimumab was linked with both clinical remission of HS and improvement of patients’ quality of life.

Download Full-text

Reliability and Validaty of St George Respiratory Questionnaire (SGRQ) into Indonesian Version

International Journal of Public Health Science (IJPHS) ◽

10.11591/ijphs.v3i3.4691 ◽

2014 ◽

Vol 3 (3) ◽

pp. 179

Author(s):

Adnan Adnan ◽

Dyah Aryani Perwitasari ◽

Ully Adhie Mulyani

Keyword(s):

Quality Of Life ◽

Factor Analysis ◽

Convergent Validity ◽

Discriminant Validity ◽

Special Instrument ◽

Convergent And Discriminant Validity ◽

Group Validity ◽

Section Design ◽

St George's Respiratory Questionnaire

Tuberculosis (TB) is one of the disease as the highest contributor to the disease burden in Indonesia. Tuberculosis can affect the patients’ quality of life, such as psychological, physical, and social functioning. St. George's Respiratory Questionnaire (SGRQ) is a special instrument which was widely used to measure the patients’ quality of life with respiratory disease. The objective of this study was to validate the Indonesian version of the SGRQ as instrument to collect data. A descriptive cross section design with 61 subjects was conducted at the Pulmonary Clinics and Primary Health Centers in the region of Yogyakarta within 3 months. The validation process included the known group validity, convergent and discriminant validity and factor analysis. There were 14 items question numbers which did not meet the criteria for convergent validity and 9 items which did not meet the criteria for discriminant validity. Known group validity analysis on gender showed that of the three domains of SGRQ, the activity domain gave statistically significant result. The factor analysis showed the result of Kaiser Meyer Olkin analysis (KMO) was less than 0.5. With a few modifications, the Indonesian version of SGRQ is valid and reliable for measuring quality of life in tuberculosis patients.

Download Full-text

Development and validation of a parent-proxy health-related quality of life survey for Australian First Nations children

BMJ Open ◽

10.1136/bmjopen-2020-046007 ◽

2021 ◽

Vol 11 (8) ◽

pp. e046007

Author(s):

Kaley Butten ◽

Lee Jones ◽

Peter A Newcombe ◽

Anne B Chang ◽

Jeanie K Sheffield ◽

...

Keyword(s):

Quality Of Life ◽

First Nations ◽

Convergent Validity ◽

Related Quality ◽

Health Related ◽

Psychological Distress Scale ◽

Distress Scale ◽

Kessler Psychological Distress Scale ◽

Parent Proxy

ObjectiveWithin Australia, Aboriginal and Torres Strait Islander (First Nations) populations perceive health and well-being differently to non-Indigenous Australians. Existing health-related quality of life (HR-QoL) measurement tools do not account for these differences. The objective of this study was to develop and validate a culturally specific parent-proxy HR-QoL measurement tool for First Nations children.DesignScale development was informed by parents/carers of children with a chronic illness and an expert panel. The preliminary 39-item survey was reviewed (n=12) and tested (n=163) with parents/carers of First Nations children aged 0–12 years at baseline with comparative scales: the Kessler Psychological Distress Scale, generic HR-QoL (Paediatric QoL Inventory 4.0, PedsQL4.0) and Spence Children’s Anxiety Scale, and repeated (n=46) 4 weeks later. Exploratory Factor Analysis was used for scale reduction. Reliability and validity were assessed by internal consistency, test–retest, and correlations with comparison scales.ResultsItems within our First Nations-Child Quality of Life (FirstNations-CQoL) were internally consistent with Cronbach’s alpha coefficients of ≥0.7 (quality of life, 0.808; patient experience, 0.880; patient support, 0.768) and overall test–retest reliability was good (r=0.75; 95% CI 0.593 to 0.856). Convergent validity was observed with the PedsQL4.0 with Pearson’s coefficients of r=0.681 (ages 2–4 years); r=0.651 (ages 5–12 years) and with the Kessler Psychological Distress scale (r=−0.513). Divergent validity against the Spence Anxiety Scale was not demonstrated.ConclusionsThe FirstNations-CQoL scale was accepted by the participants, reliable and demonstrated convergent validity with comparison measures. This tool requires further evaluation to determine responsiveness, its minimal important difference and clinical utility.

Download Full-text