An updated review on pharmacological properties of neferine—A bisbenzylisoquinoline alkaloid from Nelumbo nucifera

2021 ◽  
Author(s):  
Lohanathan Bharathi Priya ◽  
Chih‐Yang Huang ◽  
Rouh‐Mei Hu ◽  
Balamuralikrishnan Balasubramanian ◽  
Rathinasamy Baskaran
Keyword(s):  
Nelumbo Nucifera ◽  
Pharmacological Properties ◽  
Bisbenzylisoquinoline Alkaloid

Neferine, a bisbenzylisoquinoline alkaloid of Nelumbo nucifera, inhibits glutamate release in rat cerebrocortical nerve terminals through 5-HT1A receptors

2020 ◽  
Vol 889 ◽  
pp. 173589
Author(s):  
Kun Chieh Yeh ◽  
Chi Feng Hung ◽  
Ya Fan Lin ◽  
Der Chen Chang ◽  
Ming Shang Pai ◽  
...  
Keyword(s):  
Glutamate Release ◽  
Nelumbo Nucifera ◽  
Nerve Terminals ◽  
Bisbenzylisoquinoline Alkaloid

scholarly journals Mode of Action Analyses of Neferine, a Bisbenzylisoquinoline Alkaloid of Lotus (Nelumbo nucifera) against Multidrug-Resistant Tumor Cells

2017 ◽  
Vol 8 ◽  
Author(s):  
Onat Kadioglu ◽  
Betty Y. K. Law ◽  
Simon W. F. Mok ◽  
Su-Wei Xu ◽  
Thomas Efferth ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Mode Of Action ◽  
Multidrug Resistant ◽  
Nelumbo Nucifera ◽  
Bisbenzylisoquinoline Alkaloid

Effect of Nelumbo nucifera on nitric oxide production and co-stimulatory molecules

Planta Medica ◽  
2009 ◽  
Vol 75 (09) ◽  
Author(s):  
D Mukherjee ◽  
TN Khatua ◽  
A Biswas ◽  
T Biswas ◽  
BP Saha ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Nelumbo Nucifera ◽  
Nitric Oxide Production ◽  
Oxide Production

Pharmacologically potentials of different substituted coumarin derivatives

2019 ◽  
Author(s):  
Chem Int
Keyword(s):  
Benzene Ring ◽  
Bioactive Compounds ◽  
Biological Activities ◽  
Pharmacological Properties ◽  
Coumarin Derivatives ◽  
Wide Range ◽  
Anti Oxidant ◽  
Anti Inflammatory ◽  
Coumarin Compounds

Coumarin and its derivatives are widely spread in nature. Coumarin goes to agroup as benzopyrones, which consists of a benzene ring connected to a pyronemoiety. Coumarins displayed a broad range of pharmacologically useful profile.Coumarins are considered as a promising group of bioactive compounds thatexhibited a wide range of biological activities like anti-microbial, anti-viral,antiparasitic, anti-helmintic, analgesic, anti-inflammatory, anti-diabetic, anticancer,anti-oxidant, anti-proliferative, anti-convulsant, and antihypertensiveactivities etc. The coumarin compounds have immense interest due to theirdiverse pharmacological properties. In particular, these biological activities makecoumarin compounds more attractive and testing as novel therapeuticcompounds.

ASSESSMENT OF TOXICITY OF GERMANIUM COORDINATION COMPOUNDS

2019 ◽  
pp. 16-21
Author(s):  
A. V. Kadomtsevа ◽  
I. V. Zhdanovich ◽  
M. S. Piskunovа ◽  
A. N. Lineva ◽  
A. N. Novikova ◽  
...  
Keyword(s):  
Coordination Compounds ◽  
Organometallic Compounds ◽  
Biologically Active ◽  
Pharmacological Properties ◽  
Toxicological Studies ◽  
Methods Of Synthesis ◽  
Promising Area

The synthesis of biologically active coordination compounds and the design on their basis of effective pharmacological preparations is currently the promising area. This paper presents the results of the toxicological studies on digermanium and its complex derivatives. It should be noted that the positive medical properties of organometallic compounds of germanium are confirmed by numerous studies, therefore, the development of the methods of synthesis, as well as investigations of physicochemical and pharmacological properties of these compounds are at the center of attention.

Biologically Active 2,5-Disubstituted-1,3,4-Oxadiazoles

2009 ◽  
Vol 2 (1) ◽  
pp. 390-406
Author(s):  
Harish Rajak ◽  
Murli Dhar Kharya ◽  
Pradeep Mishra
Keyword(s):  
Heterocyclic Compounds ◽  
Medical Literature ◽  
Biological Activities ◽  
Biologically Active ◽  
Pharmacological Properties ◽  
Clinical Use ◽  
Synthetic Drugs ◽  
Physiologic Activity ◽  
Pharmacologically Active

There are vast numbers of pharmacologically active heterocyclic compounds in regular clinical use. The presence of heterocyclic structures in diverse types of compounds is strongly indicative of the profound effects such structure exerts on physiologic activity, and recognition of this is abundantly reflected in efforts to find useful synthetic drugs. The 1,3,4-oxadiazole nucleus has emerged as one of the potential pharmacophore responsible for diverse pharmacological properties. Medical Literature is flooded with reports of a variety of biological activities of 2,5-Disubstituted-1,3,4-oxadiazoles. The present work is an attempt to summarize and enlist the various reports published on biologically active 2,5-disubstituted-1,3,4-oxadiazoles.

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