Effects of selective breeding for voluntary exercise, chronic exercise, and their interaction on muscle attachment site morphology in house mice

2021 ◽  
Author(s):  
Alberto A. Castro ◽  
Fotios Alexandros Karakostis ◽  
Lynn E. Copes ◽  
Holland E. McClendon ◽  
Aayushi P. Trivedi ◽  
...  
Keyword(s):  
Selective Breeding ◽  
Attachment Site ◽  
Voluntary Exercise ◽  
House Mice ◽  
Chronic Exercise ◽  
Muscle Attachment

scholarly journals Effects of Selective Breeding for Voluntary Exercise, Chronic Exercise, and Their Interaction on Muscle Attachment Site Morphology in House Mice

2020 ◽  
Vol 34 (S1) ◽  
pp. 1-1
Author(s):  
Alberto A. Castro ◽  
Holland E. McClednon ◽  
Aayushi P. Trivedi ◽  
Nicolas L. Schwartz ◽  
Theodore Garland
Keyword(s):  
Selective Breeding ◽  
Attachment Site ◽  
Voluntary Exercise ◽  
House Mice ◽  
Chronic Exercise ◽  
Muscle Attachment

Rapid and longer‐term effects of selective breeding for voluntary exercise behavior on skeletal morphology in house mice

2020 ◽  
Author(s):  
Alberto A. Castro ◽  
Hannah Rabitoy ◽  
Gerald C. Claghorn ◽  
Theodore Garland
Keyword(s):  
Selective Breeding ◽  
Exercise Behavior ◽  
Voluntary Exercise ◽  
House Mice ◽  
Skeletal Morphology

Effects of Selective Breeding, Voluntary Exercise, and Sex on Endocannabinoid Levels in the Mouse Small-Intestinal Epithelium

2021 ◽  
pp. 113675
Author(s):  
Margaret P. Schmill ◽  
Zoe Thompson ◽  
Donovan A. Argueta ◽  
Nicholas V. DiPatrizio ◽  
Theodore Garland
Keyword(s):  
Intestinal Epithelium ◽  
Selective Breeding ◽  
Voluntary Exercise ◽  
Small Intestinal Epithelium ◽  
Small Intestinal

Marked for life: muscle attachment site patterns in blowfly larvae are constant throughout development

2012 ◽  
Vol 112 (1) ◽  
pp. 347-355 ◽  
Author(s):  
Senta Niederegger ◽  
Anton Miroschnikow ◽  
Roland Spieß
Keyword(s):  
Attachment Site ◽  
Muscle Attachment

scholarly journals WNT5 Interacts with the Ryk Receptors Doughnut and Derailed to Mediate Muscle Attachment Site Selection in Drosophila melanogaster

PLoS ONE ◽  
2012 ◽  
Vol 7 (3) ◽  
pp. e32297 ◽  
Author(s):  
Liza L. Lahaye ◽  
Rene R. Wouda ◽  
Anja W. M. de Jong ◽  
Lee G. Fradkin ◽  
Jasprina N. Noordermeer
Keyword(s):  
Drosophila Melanogaster ◽  
Site Selection ◽  
Attachment Site ◽  
Muscle Attachment

Macluritid opercula (Gastropoda) from the Middle Ordovician of Siberia and Alaska

1997 ◽  
Vol 71 (3) ◽  
pp. 394-400 ◽  
Author(s):  
David M. Rohr ◽  
A. P. Gubanov
Keyword(s):  
Attachment Site ◽  
Retractor Muscle ◽  
Taimyr Peninsula ◽  
Muscle Attachment ◽  
Middle Ordovician

Two occurrences of Middle Ordovician opercula belonging to the gastropod Maclurites are described, one from the Taimyr Peninsula, Siberia, and one from the Kuskokwim Mountains, Alaska. The Taimyr opercula are the first to be described from Russia. Like other opercula of the genus, these thick specimens have a relatively massive prong on the interior to which the retractor muscle was attached. The Alaskan specimens preserve a secondary muscle attachment site. The described occurrences of Maclurites opercula are summarized.

scholarly journals Coadaptation of the chemosensory system with voluntary exercise behavior in mice

PLoS ONE ◽  
2020 ◽  
Vol 15 (11) ◽  
pp. e0241758
Author(s):  
Quynh Anh Thi Nguyen ◽  
David Hillis ◽  
Sayako Katada ◽  
Timothy Harris ◽  
Crystal Pontrello ◽  
...  
Keyword(s):  
Selective Breeding ◽  
Wheel Running ◽  
Vomeronasal Organ ◽  
Voluntary Exercise ◽  
Wild Mice ◽  
Chemosensory System ◽  
Chemosensory Receptors ◽  
Receptor Clusters ◽  
Rewarding Behavior ◽  
And Control

Ethologically relevant chemical senses and behavioral habits are likely to coadapt in response to selection. As olfaction is involved in intrinsically motivated behaviors in mice, we hypothesized that selective breeding for a voluntary behavior would enable us to identify novel roles of the chemosensory system. Voluntary wheel running (VWR) is an intrinsically motivated and naturally rewarding behavior, and even wild mice run on a wheel placed in nature. We have established 4 independent, artificially evolved mouse lines by selectively breeding individuals showing high VWR activity (High Runners; HRs), together with 4 non-selected Control lines, over 88 generations. We found that several sensory receptors in specific receptor clusters were differentially expressed between the vomeronasal organ (VNO) of HRs and Controls. Moreover, one of those clusters contains multiple single-nucleotide polymorphism loci for which the allele frequencies were significantly divergent between the HR and Control lines, i.e., loci that were affected by the selective breeding protocol. These results indicate that the VNO has become genetically differentiated between HR and Control lines during the selective breeding process. Although the role of the vomeronasal chemosensory receptors in VWR activity remains to be determined, the current results suggest that these vomeronasal chemosensory receptors are important quantitative trait loci for voluntary exercise in mice. We propose that olfaction may play an important role in motivation for voluntary exercise in mammals.

derailed is required for muscle attachment site selection in Drosophila

Development ◽  
1996 ◽  
Vol 122 (9) ◽  
pp. 2761-2767 ◽  
Author(s):  
C.A. Callahan ◽  
J.L. Bonkovsky ◽  
A.L. Scully ◽  
J.B. Thomas
Keyword(s):  
Tyrosine Kinase ◽  
Family Member ◽  
Receptor Tyrosine Kinase ◽  
Site Selection ◽  
Molecular Level ◽  
Attachment Site ◽  
Small Subset ◽  
Muscle Attachment ◽  
Attachment Sites ◽  
Receptor Tyrosine Kinase Family

During development, muscles must form and attach at highly stereotyped positions to allow for coordinated movements. In Drosophila, muscles grow towards and attach to specifically positioned cells within the epidermis. At the molecular level, very little is known about how muscles recognize these attachment sites. The derailed gene encodes a receptor tyrosine kinase family member that is essential for the pathfinding ability of expressing neurons. Here we show that the Drl RTK is also expressed by a small subset of developing embryonic muscles and neighboring epidermal cells during muscle attachment site selection. In drl mutants, these muscles often fail to attach at appropriate locations although their epidermal attachment cells appear unaffected. These results show that, similar to its role in neuronal pathway recognition, the Drl RTK participates in a mechanism required for muscle attachment site selection. The data suggest that both neurons and muscles use common mechanisms to recognize their paths or targets, and that Drl plays an analogous role in both developing systems.

scholarly journals Effects of selective breeding for high voluntary wheel-running behavior on femoral nutrient canal size and abundance in house mice

2018 ◽  
Vol 233 (2) ◽  
pp. 193-203 ◽  
Author(s):  
Nicolas L. Schwartz ◽  
Biren A. Patel ◽  
Theodore Garland ◽  
Angela M. Horner
Keyword(s):  
Selective Breeding ◽  
Wheel Running ◽  
House Mice ◽  
Voluntary Wheel Running ◽  
Voluntary Wheel
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