Positive peritoneal cytology at interval surgery is a poor prognostic factor in patients with stage T3c advanced ovarian carcinoma: A retrospective study

2014 ◽  
Vol 41 (5) ◽  
pp. 755-762 ◽  
Author(s):  
Kazunori Nagasaka ◽  
Kei Kawana ◽  
Kensuke Tomio ◽  
Tetsushi Tsuruga ◽  
Mayuyo Mori-Uchino ◽  
...  
Author(s):  
Satoe Fujiwara ◽  
Ruri Nishie ◽  
Shoko Ueda ◽  
Syunsuke Miyamoto ◽  
Shinichi Terada ◽  
...  

Abstract Background There is uncertainty surrounding the prognostic value of peritoneal cytology in low-risk endometrial cancer, especially in laparoscopic surgery. The objective of this retrospective study is to determine the prognostic significance of positive peritoneal cytology among patients with low-risk endometrial cancer and to compare it between laparoscopic surgery and conventional laparotomy. Methods From August 2008 to December 2019, all cases of pathologically confirmed stage IA grade 1 or 2 endometrial cancer were reviewed at Osaka Medical College. Statistical analyses used the Chi-square test and the Kaplan–Meier log rank. Results A total of 478 patients were identified: 438 with negative peritoneal cytology (232 who underwent laparotomy and 206 who undertook laparoscopic surgery) and 40 with positive peritoneal cytology (20 who underwent laparotomy and 20 who received laparoscopic surgery). Survival was significantly worse among patients with positive peritoneal cytology compared to patients with negative peritoneal cytology. However, there was no significant difference among patients with negative or positive peritoneal cytology between laparoscopic surgery and laparotomy. Conclusion This retrospective study suggests that, while peritoneal cytology is an independent risk factor in patients with low-risk endometrial cancer, laparoscopic surgery does not influence the survival outcome when compared to laparotomy.


2010 ◽  
Vol 20 (1) ◽  
pp. 28-33 ◽  
Author(s):  
Alexandre Labiche ◽  
Natacha Heutte ◽  
Paulette Herlin ◽  
Jacques Chasle ◽  
Pascal Gauduchon ◽  
...  

2015 ◽  
Vol 59 (2) ◽  
pp. 201-206 ◽  
Author(s):  
Tomoko Kurita ◽  
Yusuke Matsuura ◽  
Chiho Koi ◽  
Seiji Kagami ◽  
Toshinori Kawagoe ◽  
...  

Objective: We investigated the association of positive peritoneal cytology with prognosis in uterine cervical cancer. Study Design: We reviewed the medical records and cytologic materials of 225 Japanese patients with FIGO IB1-IVB uterine cervical cancer who had undergone surgery at our University Hospital between 1993 and 2012. Univariate and multivariate regression analyses were performed for statistical analysis. Results: Positive peritoneal cytology was noted in 6 of 225 patients (2.7%). Positive peritoneal cytology was found in 4 of 149 patients (2.6%) with squamous cell carcinoma (SCC) and in 2 of 70 patients (2.8%) with non-SCC (p = 0.9434). The 5-year survival rate of patients with positive peritoneal cytology was significantly lower than that of patients with negative cytology (50 vs. 84.6%, p = 0.001) in univariate survival analysis. However, peritoneal cytology no longer remained significant in multivariate analysis. Conclusion: Although we conclude that positive peritoneal cytology in uterine cervical cancer is a poor prognostic factor, further investigation and multi-institutional studies are necessary.


1996 ◽  
Vol 62 (2) ◽  
pp. 208-212 ◽  
Author(s):  
Gerardo Zanetta ◽  
Gary L. Keeney ◽  
Stephen S. Cha ◽  
Harry S. Wieand ◽  
Jerry A. Katzmann ◽  
...  

PLoS ONE ◽  
2012 ◽  
Vol 7 (4) ◽  
pp. e33674 ◽  
Author(s):  
Ling-Min Liao ◽  
Xin Zhang ◽  
Yu-Feng Ren ◽  
Xiao-Ying Sun ◽  
Na Di ◽  
...  

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