Antioxidant supplementation of low-protein diets reduced susceptibility to pulmonary hypertension in broiler chickens raised at high altitude

2015 ◽  
Vol 100 (1) ◽  
pp. 69-76 ◽  
Author(s):  
M. R. Sharifi ◽  
F. Khajali ◽  
H. Hassanpour
2005 ◽  
Vol 14 (4) ◽  
pp. 665-669 ◽  
Author(s):  
A. Torres-Rodriguez ◽  
C. Sartor ◽  
S.E. Higgins ◽  
A.D. Wolfenden ◽  
L.R. Bielke ◽  
...  

2009 ◽  
Vol 57 (2) ◽  
pp. 229-238 ◽  
Author(s):  
Hossein Hassanpour ◽  
Abdol Moghaddam ◽  
Hamed Zarei

To clarify the effect of orally administered citric acid on the electrocardiographic parameters of pulmonary hypertensive broilers, chicks were reared at high altitude and treated with citric acid for 45 days. Increase of cardiac indices such as right ventricle/total ventricles (RV/TV), RV/body weight and TV/body weight ratio was not observed in the treated groups as compared to the control groups. Decrease of S amplitude in the treated groups (leads II, III, aVF) was only significant (P < 0.05) at 45 days of age (leads II, aVF; 1.5 g/l of citric acid). There were significant reductions of T amplitude at 28 (lead aVR) and 36 days (lead aVL) and significant reductions of R wave at 28 (lead aVL, all doses of citric acid) and 45 days of age (lead aVR, 1 and 1.5 g/l citric acid) in the treated groups. The QRS interval was significantly higher at 28 (leads III and aVF), 36 (leads II, III and aVF, 1 g/l citric acid) and 45 days of age (leads II and aVF) in the treated groups. The QT interval was significantly (P < 0.05) increased at 28 and 45 days of age (lead aVL) and the RR interval also showed an increase at 28 (leads aVR and aVL) and 45 (lead aVL) days of age as compared to the controls. Our data indicate that citric acid modulates the induction of pulmonary hypertension at high altitude and this effect is detectable in the electrocardiographic parameters.


2011 ◽  
Vol 49 (No. 10) ◽  
pp. 436-443 ◽  
Author(s):  
P. Zobač ◽  
I. Kumprecht ◽  
P. Suchý ◽  
E. Straková ◽  
J. Brož ◽  
...  

Two growth trials and a short-term metabolism trial were conducted in broiler chickens in the period of 22 to 42 days of age in order to evaluate the effects of two dietary levels of L-lactic acid (1.03 or 2.06 g/kg) and microbial 6-phytase (750 U/kg), added either separately or in combination, on growth rate, feed conversion, dressing percentage and utilization of selected nutrients. In the first growth trial, six different dietary treatments were added to a basal grower diet containing 19.4% crude protein and a reduced level of dietary phosphorus (P) (5.9 g total and 2.9 g non-phytate P per kg). Single administration of L-lactic acid did not show any positive effect on the growth rate or feed conversion. In contrast, phytase addition to a low-P grower diet resulted in the increased final weight of birds and higher feed conversion. This beneficial effect was markedly stronger when the microbial phytase was added to the diets containing L-lactic acid. Based on two-factor analysis of variance, microbial phytase significantly increased the mean final weight by 6.5% (P &lt; 0.01) and significantly improved feed conversion from 1.877 to 1.829 (P &lt; 0.05). In the second growth trial, the same six dietary treatments were added to a basal diet containing a standard level of dietary P (6.7 g total and 4.0 g non-phytate P per kg), but the level of crude protein was reduced to 17.0%. L-lactic acid alone did not show any positive effects on performance. Phytase supplementation alone resulted in numerical improvement of the final weight (+1.1&ndash;2.4%), but a higher effect was observed in the diets containing L-lactic acid. In agreement with the reduced final weights of broilers fed the low-protein diets, markedly higher values of feed/gain ratio were noted. In the metabolism trial, selected dietary treatments were involved to evaluate the effects of L-lactic acid and microbial phytase, added either separately or in combination, on the digestibility of nitrogen (N) and fat as well as on the retention and excretion of N and P. Apparent digestibility of N and fat in the low-P diets was not affected by dietary treatments. Retention and utilization of N were numerically higher in all treatments fed low-P diets when compared to the treatment fed a standard diet, but the differences were not significant. Retention of P was numerically higher in all treatments fed low-P diets. When compared to the standard diet, the combination of phytase and L-lactic acid increased daily P retention by 37.6%. P excretion was significantly (P &lt; 0.05) reduced in all treatments fed low-P diets supplemented by both test products, either separately or in combination. A numerical decrease in N excretion was noted in both treatments fed low-protein diets. &nbsp; &nbsp;


2017 ◽  
Vol 57 (11) ◽  
pp. 2250 ◽  
Author(s):  
S. Y. Liu ◽  
P. H. Selle

Digestive dynamics of starch and protein is defined as digestion of starch and protein, absorption of glucose and amino acids from the gut lumen and their transition across enterocytes to enter the portal circulation. Digestive dynamics consider the extent, rate and site of nutrient digestion along the small intestine and the bilateral, post-enteral bioavailability of glucose and amino acids. The underlying premise is that glucose and amino acids should be made available in appropriately balanced quantities at the sites of protein synthesis for efficient protein deposition and growth performance. Previous studies have suggested that feed conversion efficiency may be enhanced by rapidly digestible protein and that crystalline amino acids could be considered sources of ‘rapid protein’. At present, crystalline lysine, methionine and threonine are routinely included in broiler diets; moreover, an increasing array of both essential and non-essential crystalline amino acids is becoming commercially available. Despite unrestricted feed access in commercial chicken-meat production systems during the period of illumination, it appears that the intermittent feed consumption patterns of broiler chickens still provide scope for asynchronies in digestion and absorption of nutrients, which affects broiler performance. A better understanding of the post-enteral, bilateral bioavailability of glucose and amino acids in low-protein diets containing high levels of synthetic amino acids is clearly desirable and this applies equally to the relationship between crystalline and protein-bound amino acids.


2018 ◽  
Vol 31 (8) ◽  
pp. 1291-1300 ◽  
Author(s):  
Fang Lin Law ◽  
Idrus Zulkifli ◽  
Abdoreza Farjam Soleimani ◽  
Juan Boo Liang ◽  
Elmutaz Atta Awad

2017 ◽  
Vol 96 (4) ◽  
pp. 914-922 ◽  
Author(s):  
I.C. Ospina-Rojas ◽  
A.E. Murakami ◽  
C.R.A. Duarte ◽  
G.R. Nascimento ◽  
E.R.M. Garcia ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document