The role of gut microbiota in hepatitis B disease progression and treatment

2021 ◽  
Author(s):  
Bryan Chen ◽  
Harry Huang ◽  
Calvin Q. Pan
2013 ◽  
Vol 16 (5) ◽  
pp. 435-437 ◽  
Author(s):  
J. Alfredo Martínez ◽  
Usune Etxeberría ◽  
Alicia Galar ◽  
Fermín I. Milagro

2020 ◽  
Vol 21 ◽  
Author(s):  
Tingting Zhao ◽  
Zhe Wang ◽  
Zhilong Liu ◽  
Youhua Xu

: With the recognition of the important role of gut microbiota in both health and disease progression, attempts to modulate its composition as well as its co-metabolism with the organism have attracted special attention. Abundant studies have demonstrated that dysfunction or imbalance of gut microbiota is closely with disease including endocrine diseases, neurodegenerative diseases, tumors, cardiovascular diseases, et al. Herbal medicines have been applied for preventing and treating disease worldwide for hundreds of years. Although the underlying mechanism seems to be complex, one of the important one is through modulating gut microbiota. In this review, co-metabolism between herbal medicines and microbiota, as well as the potential pathways are summarized from most recent published papers.


2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Ruilin Yang ◽  
Yao Xu ◽  
Zhifeng Dai ◽  
Xuhong Lin ◽  
Huichao Wang

Hepatitis B can cause acute or chronic liver damage due to hepatitis B virus (HBV) infection. Cirrhosis or hepatocellular carcinoma (HCC) caused by chronic HBV infection often leads to increased mortality. However, the gut and liver have the same embryonic origin; therefore, a close relationship must exist in terms of anatomy and function, and the gut microbiota plays an important role in host metabolic and immune modulation. It is believed that structural changes in the gut microbiota, bacterial translocation, and the resulting immune injury may affect the occurrence and development of liver inflammation caused by chronic HBV infection based on the in-depth cognition of the concept of the “gut-liver axis” and the progress in intestinal microecology. This review aims to summarize and discuss the immunologic role of the gut microbiota in chronic HBV infection.


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