scholarly journals Risk Factors for Recurrence of Atrial Fibrillation in Horses After Cardioversion to Sinus Rhythm

2015 ◽  
Vol 29 (3) ◽  
pp. 946-953 ◽  
Author(s):  
A. Decloedt ◽  
C.C. Schwarzwald ◽  
D. De Clercq ◽  
N. Van Der Vekens ◽  
B. Pardon ◽  
...  
Keyword(s):  
Risk Factors ◽  
Atrial Fibrillation ◽  
Sinus Rhythm ◽  
Risk Factors For Recurrence

scholarly journals Mechanism of and Therapeutic Strategy for Atrial Fibrillation Associated with Diabetes Mellitus

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Yubi Lin ◽  
Hairui Li ◽  
Xianwu Lan ◽  
Xianghui Chen ◽  
Aidong Zhang ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Atrial Fibrillation ◽  
Catheter Ablation ◽  
Sinus Rhythm ◽  
Renin Angiotensin System ◽  
Hypoglycemic Agents ◽  
Angiotensin System ◽  
Low Levels ◽  
Upstream Therapy

Diabetes mellitus (DM) is one of the most important risk factors for atrial fibrillation (AF) and is a predictor of stroke and thromboembolism. DM may increase the incidence of AF, and when it is combined with other risk factors, the incidence of stroke and thromboembolism may also be higher; furthermore, hospitalization due to heart failure appears to increase. Maintenance of well-controlled blood glucose and low levels of HbA1c in accordance with guidelines may decrease the incidence of AF. The mechanisms of AF associated with DM are autonomic remodeling, electrical remodeling, structural remodeling, and insulin resistance. Inhibition of the renin-angiotensin system is suggested to be an upstream therapy for this type of AF. Studies have indicated that catheter ablation may be effective for AF associated with DM, restoring sinus rhythm and improving prognosis. Catheter ablation combined with hypoglycemic agents may further increase the rate of maintenance of sinus rhythm and reduce the need for reablation.

scholarly journals Atrial Fibrillation in Hypertrophic Cardiomyopathy

2021 ◽  
Vol 11 (3) ◽  
pp. 173-185
Author(s):  
G. A. Ignatenko ◽  
G. G. Taradin ◽  
N. T. Vatutin ◽  
A. A. Kaluga ◽  
Yu. D. Kostyamin
Keyword(s):  
Risk Factors ◽  
Atrial Fibrillation ◽  
Radiofrequency Ablation ◽  
Hypertrophic Cardiomyopathy ◽  
Sinus Rhythm ◽  
Antiarrhythmic Drugs ◽  
Contemporary Literature ◽  
Clinical Manifestations ◽  
Detection Methods

The current information about features of atrial fibrillation in patients with hypertrophic cardiomyopathy is presented in this review. The data about prevalence, pathogenesis and its various complications in these patients are disclosed. The article contains updated clinical recommendations of authoritative medical societies on the discussing problem. There is detailed discussion of risk factors of atrial fibrillation onset in setting of hypertrophic cardiomyopathy with demonstration of results of different studies concerning to investigation of relationship between risk factors and probability of the arrhythmia development. There is description of detection methods, clinical manifestations, and the course of atrial fibrillation in patients with hypertrophic cardiomyopathy. The contemporary literature data are presented regarding to the management of patients with atrial fibrillation with use of anticoagulants, antiarrhythmic drugs, indications for performing of radiofrequency ablation and results of studies concerning long-term efficacy of such procedure are demonstrated. The discussion on the management of the patients in cases of sinus rhythm restoration or maintenance failure is described.

Atrial fibrillation and hyperthyroidism

ESC CardioMed ◽  
2018 ◽  
pp. 2229-2232
Author(s):  
Bernadette Biondi
Keyword(s):  
Risk Factors ◽  
Atrial Fibrillation ◽  
Blood Pressure ◽  
Heart Disease ◽  
Sinus Rhythm ◽  
Graves Disease ◽  
Multinodular Goitre ◽  
Lower Systolic Blood Pressure ◽  
History Of ◽  
Hyperthyroid Patients

Atrial fibrillation develops in about 10–25% of patients with hyperthyroidism with a higher risk in patients with toxic multinodular goitre compared to those with Graves disease. Advanced age, history of cardiac failure, and presence of associated cardiovascular risk factors represent independent predictors for the development of atrial fibrillation. Spontaneous reversion to sinus rhythm frequently occurs in successfully treated hyperthyroid patients under 50 years of age with newly diagnosed atrial fibrillation, without underlying heart disease and lower systolic blood pressure. In contrast, atrial fibrillation persisting for 4 months or more after the control of hyperthyroidism rarely reverts to sinus rhythm in mainly elderly patients and in those with heart disease.

Atrial fibrillation progression and prevention

ESC CardioMed ◽  
2018 ◽  
pp. 2135-2139
Author(s):  
Justin G. L. M. Luermans ◽  
Jordi Heijman ◽  
Isabelle C. Van Gelder ◽  
Harry J. G. M. Crijns
Keyword(s):  
Risk Factors ◽  
Atrial Fibrillation ◽  
Sinus Rhythm ◽  
Clinical Significance ◽  
Cardiovascular Events ◽  
Therapeutic Options ◽  
Major Adverse Cardiovascular Events ◽  
Pathophysiological Mechanisms ◽  
Underlying Mechanisms ◽  
Sinus Rhythm Maintenance

Atrial fibrillation (AF) patients are commonly classified into five groups, first-diagnosed, paroxysmal, persistent, long-standing persistent, or permanent AF, based on the duration of AF and clinical conventions. Progression of AF to longer-lasting forms is common and has important clinical significance, affecting both the success of sinus rhythm maintenance and the occurrence of major adverse cardiovascular events. As such, there is considerable interest in the underlying mechanisms and therapeutic options to prevent AF progression. This chapter discusses the epidemiology, risk factors, and clinical significance of AF progression. It also provides background on the pathophysiological mechanisms of AF progression and highlights options for its management and prevention.

Atrial fibrillation and hyperthyroidism

ESC CardioMed ◽  
2018 ◽  
pp. 2229-2232
Author(s):  
Bernadette Biondi
Keyword(s):  
Risk Factors ◽  
Atrial Fibrillation ◽  
Blood Pressure ◽  
Heart Disease ◽  
Sinus Rhythm ◽  
Graves Disease ◽  
Multinodular Goitre ◽  
Lower Systolic Blood Pressure ◽  
History Of ◽  
Hyperthyroid Patients

Atrial fibrillation develops in about 10–25% of patients with hyperthyroidism with a higher risk in patients with toxic multinodular goitre compared to those with Graves disease. Advanced age, history of cardiac failure, and presence of associated cardiovascular risk factors represent independent predictors for the development of atrial fibrillation. Spontaneous reversion to sinus rhythm frequently occurs in successfully treated hyperthyroid patients under 50 years of age with newly diagnosed atrial fibrillation, without underlying heart disease and lower systolic blood pressure. In contrast, atrial fibrillation persisting for 4 months or more after the control of hyperthyroidism rarely reverts to sinus rhythm in mainly elderly patients and in those with heart disease.

Abstract 15729: Effect of Metformin on Outcomes of Catheter Ablation for Atrial Fibrillation

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Amrish Deshmukh ◽  
Elif Oral ◽  
Michael Ghannam ◽  
Jackson Liang ◽  
Mohammed Saeed ◽  
...  
Keyword(s):  
Risk Factors ◽  
Atrial Fibrillation ◽  
Blood Glucose ◽  
Catheter Ablation ◽  
Glycemic Control ◽  
Sinus Rhythm ◽  
Left Atrial ◽  
Fasting Blood Glucose ◽  
Lower Probability ◽  
Left Atrial Diameter

Background: Diabetes mellitus (DM) and glycemic control are risk factors for atrial fibrillation (AF). Metformin may have antifibrillatory properties by altering atrial metabolism. It is unknown whether metformin has favorable effects on the outcomes of catheter ablation (CA) for AF. Objective: To determine whether metformin use is associated with maintenance of sinus rhythm after CA for AF. Methods and Results: A 1 st CA was performed in 271 consecutive patients with DM and AF (age: 65±9 years, women: 34 %; and paroxysmal AF: 50%). A total of 182 (67%) patients were treated with metformin and 79/182 were also receiving other antidiabetics or insulin. HbA1c and preprocedural fasting blood glucose were similar among the patients treated with and without metformin (7.2±1.4% vs. 7.2±1.3%, P=0.95 and 162± 61 vs. 159±66 mg/dL, P=0.72). At a median of 10 months (IQR: 5-23, mean 15±13 months) after CA, 100/182 patients (55%) on metformin remained in sinus rhythm without concomitant antiarrhythmic drugs (AAD) compared to 36/89 patients (40%) not receiving metformin (P=0.03). On K-M analysis, patients on metformin were more likely to stay in sinus rhythm after CA, with or without AADs (P<0.001, log-rank, Figure). On Cox proportional hazards analysis, adjusted for age, gender, BMI, type of AF(paroxysmal vs. non-paroxysmal), fasting blood glucose, AAD use, obstructive sleep apnea, chronic kidney disease, and left atrial diameter, metformin use was associated with a ~35% lower probability of recurrent atrial arrhythmia(HR: 0.65, ±95% CI: 0.44-0.97, P=0.04). Increase in left atrial diameter (per mm, HR: 1.05, ±95% CI:1.01-1.08, P=0.001) and non-paroxysmal AF (HR: 1.9, ±95% CI: 1.3-2.9, P=0.001) were associated with a higher risk of recurrence after CA of AF. Conclusion: In patients with DM, the use of metformin was associated with a significant reduction in recurrent atrial arrhythmias after CA for AF independent of the other risk factors, including preprocedural glycemic control.

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