Control of the inflammatory response during pregnancy: potential role of VIP as a regulatory peptide

2018 ◽  
Vol 1437 (1) ◽  
pp. 15-21 ◽  
Author(s):  
Rosanna Ramhorst ◽  
Guillermina Calo ◽  
Daniel Paparini ◽  
Daiana Vota ◽  
Vanesa Hauk ◽  
...  
2020 ◽  
Vol 11 (10) ◽  
pp. 9252-9262 ◽  
Author(s):  
Zhigang Zhang ◽  
Changming Guo ◽  
Huijie Jiang ◽  
Bing Han ◽  
Xiaoqiao Wang ◽  
...  

Schematic diagram of the mechanism of post treatment with natural astaxanthin attenuating arsenic-induced inflammatory response in rat liver.


Toxicon ◽  
2012 ◽  
Vol 60 (2) ◽  
pp. 172 ◽  
Author(s):  
Sonia Adi-Bessalem ◽  
Amina Ladjal-Mendil ◽  
Djelila Hammoudi-Triki ◽  
Fatima Laraba-Djebari

1975 ◽  
Vol 142 (3) ◽  
pp. 709-721 ◽  
Author(s):  
J Siegel ◽  
A P Osmand ◽  
M F Wilson ◽  
H Gewurz

Cationic homopolymers of poly-L-lysine were found to activate complement (C) via C-reactive protein (CRP) and deplete C3 and C5 as well as early-acting C components. Maximum C consumption was obtained with polymers of 2,000-8,000 daltons; polymers of 1,700, 11,000, and 23,000 daltons were intermediate in reactivity, while L-lysine, lysyl-L-lysine, tetra-L-lysine, and polymers of 70,000-400,000 daltons lacked significant C-consuming activity. Naturally occurring polycations which consumed C in the presence of CRP included myelin basic proteins, cationic proteins of rabbit leukocytes, and both lysine- and arginine-rich histones; poly-L-arginine polymers of 17,000 but not 65,000 daltons also were C-consuming. Polycations without such reactivity included poly-L-orithine (5,000 and 165,000 daltons), egg white and human lysozymes, and Polybrene. The polycations which failed to induce C consumption via CRP, inhibited its consumption by both active polycations and by C-polysaccharide (CPS). The relative inhibitory capacity of phosphorylcholine and polycations in CPS- and polycations-CRP systems was consistent with the concept that phosphate esters and polycations react at the same or an overlapping combining site. The ability of certain polycations to activate C via CRP increases the potential for initiation of host reactions via C. The capacity of other polycations to inhibit C activation via CRP introduces a potential for physiologic or pharmacologic manipulation. These considerations would seem to expand the potential role of CRP in the initiation and modulation of the inflammatory response.


2016 ◽  
Vol 244 ◽  
pp. 187-194 ◽  
Author(s):  
Nachimuthu Maithilikarpagaselvi ◽  
Magadi Gopalakrishna Sridhar ◽  
Rathinam Palamalai Swaminathan ◽  
Bobby Zachariah

2016 ◽  
Vol 93 ◽  
pp. 12-22 ◽  
Author(s):  
Hong Sook Kim ◽  
Byung-Hak Kim ◽  
Joo Eun Jung ◽  
Chang Seok Lee ◽  
Hyun Gyu Lee ◽  
...  

2019 ◽  
Vol 68 ◽  
pp. 7-15 ◽  
Author(s):  
Felipe Zecchinati ◽  
Maria Manuela Barranco ◽  
Maite Rocío Arana ◽  
Guillermo Nicolás Tocchetti ◽  
Camila Juliana Domínguez ◽  
...  

2020 ◽  
Vol 22 (6) ◽  
pp. 5095-5104
Author(s):  
Weize Yang ◽  
Xiaomin Luo ◽  
Yu Liu ◽  
Jun Xiong ◽  
Hongxia Xia ◽  
...  

2011 ◽  
Vol 2011 ◽  
pp. 1-13 ◽  
Author(s):  
Gabriella Wojewodka ◽  
Juan B. De Sanctis ◽  
Danuta Radzioch

Patients with cystic fibrosis (CF) are afflicted with many symptoms but the greatest challenge is the fight against chronic bacterial infections, leading to decreased lung function and ultimately death. Our group has recently found reduced levels of ceramides in CF patients and mice. Ceramides are sphingolipids involved in the structure of cell membranes but also participate in the inflammatory response, in cell signalling through membrane microdomains (lipid rafts), and in apoptosis. These characteristics of ceramides make them strong candidates for therapeutic intervention in CF. As more studies have come to evaluate the role of ceramide in CF, conflicting results have been described. This paper discusses various views regarding the potential role of ceramide in CF, summarizes methods of ceramide detection and their role in the regulation of cellular and molecular processes.


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