Inflammation response after the cessation of chronic arsenic exposure and post-treatment of natural astaxanthin in liver: potential role of cytokine-mediated cell–cell interactions

2020 ◽  
Vol 11 (10) ◽  
pp. 9252-9262 ◽  
Author(s):  
Zhigang Zhang ◽  
Changming Guo ◽  
Huijie Jiang ◽  
Bing Han ◽  
Xiaoqiao Wang ◽  
...  
Keyword(s):  
Inflammatory Response ◽  
Rat Liver ◽  
Potential Role ◽  
Arsenic Exposure ◽  
Post Treatment ◽  
Cell Interactions ◽  
Schematic Diagram ◽  
Inflammation Response ◽  
Chronic Arsenic Exposure

Schematic diagram of the mechanism of post treatment with natural astaxanthin attenuating arsenic-induced inflammatory response in rat liver.

scholarly journals Transient sex-related changes in the mice hypothalamo–pituitary–adrenal (HPA) axis during the acute phase of the inflammatory process

1993 ◽  
Vol 2 (2) ◽  
pp. 123-127 ◽  
Author(s):  
T. Daneva ◽  
E. Spinedi ◽  
R. Hadid ◽  
M.-C. Jacquier ◽  
M. Giacomini ◽  
...  
Keyword(s):  
Sex Difference ◽  
Acute Phase ◽  
Hpa Axis ◽  
Plasma Levels ◽  
Potential Role ◽  
Post Treatment ◽  
Male Mice ◽  
Plasma Acth ◽  
Endogenous Sex Hormones

The potential role of endogenous sex hormones in regulating hypothalamo–pituitary–adrenal (HPA) axis function was investigated after a single injection of endotoxin in adult (8 week old) BALB/c mice of both sexes. The effect of LPS on plasma ACTH, corticosterone (B), testosterone and oestradiol (E) levels and on anterior pituitary (AP) ACTH and adrenal B contents at different times after treatment was studied. The results indicate that: (a) basal B but not ACTH plasma levels were significantly higher in female than in male mice; (b) LPS significantly increased both ACTH and B plasma levels over the baseline 2 h after injection, both hormone levels being higher in female than in male mice; (c) although plasma ACTH concentrations recovered the basal value at 72 h after LPS in animals of both sexes, plasma B levels returned to the baseline only at 120 h after treatment; (d) E plasma levels significantly increased 2 h after LPS and returned to the baseline at 72 h post-treatment, in both sexes; (e) at 2 h after LPS, testosterone plasma levels significantly decreased in male mice and increased in female mice, recovering the baseline level at 120 and 72 h after LPS, respectively; (f) AP ACTH content was similar in both sexes in basal condition and it was significantly diminished 72 h post-treatment without sex difference; whereas AP ACTH returned to basal content 120 h after LPS in males, it remained significantly decreased in females; (g) basal adrenal B content was higher in female than in male mice, and it significantly increased in both sexes 2 h post-LPS, maintaining this sex difference. Whereas adrenal B returned to basal content 72 h after treatment in male mice, it remained significantly enhanced up to 120 h post-LPS in female animals. The data demonstrate the existence of a clear sexual dimorphism in basal condition and during the acute phase response as well as in the recovery of the HPA axis function shortly after infection.

Control of the inflammatory response during pregnancy: potential role of VIP as a regulatory peptide

2018 ◽  
Vol 1437 (1) ◽  
pp. 15-21 ◽  
Author(s):  
Rosanna Ramhorst ◽  
Guillermina Calo ◽  
Daniel Paparini ◽  
Daiana Vota ◽  
Vanesa Hauk ◽  
...  
Keyword(s):  
Inflammatory Response ◽  
Potential Role ◽  
Regulatory Peptide

scholarly journals Lipid and Cholesterol Homeostasis after Arsenic Exposure and Antibiotic Treatment in Mice: Potential Role of the Microbiota

2019 ◽  
Vol 127 (9) ◽  
pp. 097002 ◽  
Author(s):  
Liang Chi ◽  
Yunjia Lai ◽  
Pengcheng Tu ◽  
Chih-Wei Liu ◽  
Jingchuan Xue ◽  
...  
Keyword(s):  
Antibiotic Treatment ◽  
Potential Role ◽  
Arsenic Exposure ◽  
Cholesterol Homeostasis

scholarly journals Potential role of post‑treatment follow‑up FDG‑PET CT to detect mandibular osteoradionecrosis: A case report

2017 ◽  
Author(s):  
Masaya Akashi ◽  
Satoshi Wanifuchi ◽  
Junya Kusumoto ◽  
Megumi Kishimoto ◽  
Yasumasa Kakei ◽  
...  
Keyword(s):  
Case Report ◽  
Fdg Pet ◽  
Potential Role ◽  
Post Treatment ◽  
Pet Ct ◽  
Fdg Pet Ct

scholarly journals Potential Role of Androgens in the Treatment of Hypoactive Sexual Desire in Women

2005 ◽  
Vol 1 (2) ◽  
pp. 191-193 ◽  
Author(s):  
Anita H Clayton
Keyword(s):  
Treatment Group ◽  
Postmenopausal Women ◽  
Clinical Experience ◽  
Sexual Desire ◽  
Potential Role ◽  
Post Treatment ◽  
Salivary Testosterone ◽  
Testosterone Levels ◽  
Group Post

Evaluation of: van Anders SM, Chernick AB, Chernick BA et al.: Preliminary clinical experience with androgen administration for pre- and postmenopausal women with hypoactive sexual desire. J. Sex Marital Ther. 31, 173–185 (2005). There has been significant debate about the potential role of androgens in the treatment of hypoactive sexual desire in women. In this study, pre- and postmenopausal women with hypoactive sexual desire were age-matched with women without such complaints (n = 33). The treatment group received 100 mg of testosterone cypionate intramuscularly once a month for 3 months. Measures of salivary testosterone indicated no difference between groups at baseline, with an increase in testosterone levels in the hypoactive sexual desire group post-treatment. While significant differences existed between the two groups at baseline in scores on the Sexual Desire Inventory, the treated women demonstrated a significant increase in sexual desire post-treatment, with no difference in Sexual Desire Inventory scores at study end point. This study suggests that supplemental testosterone may improve sexual desire in women with hypoactive sexual desire without hypoandrogenism.

151. Immuno-Inflammatory Response after Scorpion Envenomation: Potential Role of Eïcosanoids and Histamine H1-Receptor

Toxicon ◽  
2012 ◽  
Vol 60 (2) ◽  
pp. 172 ◽  
Author(s):  
Sonia Adi-Bessalem ◽  
Amina Ladjal-Mendil ◽  
Djelila Hammoudi-Triki ◽  
Fatima Laraba-Djebari
Keyword(s):  
Inflammatory Response ◽  
Potential Role ◽  
H1 Receptor ◽  
Scorpion Envenomation ◽  
Histamine H1 Receptor

scholarly journals Interactions of C-reactive protein with the complement system. II. C-reactive protein-mediated consumption of complement by poly-L-lysine polymers and other polycations.

1975 ◽  
Vol 142 (3) ◽  
pp. 709-721 ◽  
Author(s):  
J Siegel ◽  
A P Osmand ◽  
M F Wilson ◽  
H Gewurz
Keyword(s):  
Inflammatory Response ◽  
Potential Role ◽  
Egg White ◽  
Phosphate Esters ◽  
C Reactive Protein ◽  
Cationic Proteins ◽  
Reactive Protein ◽  
Naturally Occurring ◽  
The Complement System

Cationic homopolymers of poly-L-lysine were found to activate complement (C) via C-reactive protein (CRP) and deplete C3 and C5 as well as early-acting C components. Maximum C consumption was obtained with polymers of 2,000-8,000 daltons; polymers of 1,700, 11,000, and 23,000 daltons were intermediate in reactivity, while L-lysine, lysyl-L-lysine, tetra-L-lysine, and polymers of 70,000-400,000 daltons lacked significant C-consuming activity. Naturally occurring polycations which consumed C in the presence of CRP included myelin basic proteins, cationic proteins of rabbit leukocytes, and both lysine- and arginine-rich histones; poly-L-arginine polymers of 17,000 but not 65,000 daltons also were C-consuming. Polycations without such reactivity included poly-L-orithine (5,000 and 165,000 daltons), egg white and human lysozymes, and Polybrene. The polycations which failed to induce C consumption via CRP, inhibited its consumption by both active polycations and by C-polysaccharide (CPS). The relative inhibitory capacity of phosphorylcholine and polycations in CPS- and polycations-CRP systems was consistent with the concept that phosphate esters and polycations react at the same or an overlapping combining site. The ability of certain polycations to activate C via CRP increases the potential for initiation of host reactions via C. The capacity of other polycations to inhibit C activation via CRP introduces a potential for physiologic or pharmacologic manipulation. These considerations would seem to expand the potential role of CRP in the initiation and modulation of the inflammatory response.

scholarly journals The action of α-adrenergic agonists on plasma-membrane calcium fluxes in perfused rat liver

1984 ◽  
Vol 220 (1) ◽  
pp. 43-50 ◽  
Author(s):  
P H Reinhart ◽  
W M Taylor ◽  
F L Bygrave
Keyword(s):  
Plasma Membrane ◽  
Rat Liver ◽  
Potential Role ◽  
Dependent Manner ◽  
Perfused Rat Liver ◽  
Adrenergic Agonists ◽  
Mediated Effects ◽  
Alpha Agonist ◽  
Alpha Adrenergic Agonist

The effect of alpha-adrenergic agonists on Ca2+ fluxes was examined in the perfused rat liver by using a combination of Ca2+-electrode and 45Ca2+-uptake techniques. We showed that net Ca2+ fluxes can be described by the activities of separate Ca2+-uptake and Ca2+-efflux components, and that alpha-adrenergic agonists modulate the activity of both components in a time-dependent manner. Under resting conditions, Ca2+-uptake and -efflux activities are balanced, resulting in Ca2+ cycling across the plasma membrane. The alpha-adrenergic agonists vasopressin and angiotensin, but not glucagon, stimulate the rate of both Ca2+ efflux and Ca2+ uptake. During the first 2-3 min of alpha-agonist administration the effect on the efflux component is the greater, the net effect being efflux of Ca2+ from the cell. After 3-4 min of phenylephrine treatment, net Ca2+ movements are essentially complete, however, the rate of Ca2+ cycling is significantly increased. After removal of the alpha-agonist a large stimulation of the rate of Ca2+ uptake leads to the net accumulation of Ca2+ by the cell. The potential role of these Ca2+ flux changes in the expression of alpha-adrenergic-agonist-mediated effects is discussed.

Curcumin prevents inflammatory response, oxidative stress and insulin resistance in high fructose fed male Wistar rats: Potential role of serine kinases

2016 ◽  
Vol 244 ◽  
pp. 187-194 ◽  
Author(s):  
Nachimuthu Maithilikarpagaselvi ◽  
Magadi Gopalakrishna Sridhar ◽  
Rathinam Palamalai Swaminathan ◽  
Bobby Zachariah
Keyword(s):  
Oxidative Stress ◽  
Insulin Resistance ◽  
Inflammatory Response ◽  
Wistar Rats ◽  
Potential Role ◽  
High Fructose ◽  
Male Wistar Rats ◽  
Serine Kinases
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