Non-steroidal anti-inflammatory drugs for pain after oral surgery

Oral Surgery ◽  
2013 ◽  
Vol 7 (3) ◽  
pp. 152-161 ◽  
Author(s):  
E. Bailey ◽  
N. Patel ◽  
P. Coulthard
Keyword(s):  
Oral Surgery ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

scholarly journals USO DE ANALGÉSICOS Y ANTIINFLAMATORIOS EN UN SERVICIO DE CIRUGÍA BUCAL EN MEDELLÍN, 2013-2015

2019 ◽  
Vol 30 (2) ◽  
Author(s):  
Stefanía Hernández Viana ◽  
Natalia Silva Gómez ◽  
David Andrés Gálvis Pareja ◽  
María Cecilia Martínez Pabón
Keyword(s):  
Oral Surgery ◽  
Descriptive Study ◽  
Third Molars ◽  
Prescription Pattern ◽  
Drug Of Choice ◽  
Dental Practitioners ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
School Of Dentistry ◽  
Clinical Records

Introduction: dental surgical procedures trigger an inflammatory response, for which dental practitioners prescribe analgesic and anti-inflammatory medications using pharmacological guidelines that require knowledge on the use of medicines in a given environment. The aim of the present study was to identify the analgesics and anti-inflammatory drugs most commonly prescribed at the oral surgery service of the Universidad de Antioquia School of Dentistry. Methods: this retrospective descriptive study reviewed the clinical records of the oral surgery service in the period January 2013-August 2015. A total of 1,177 records were reviewed, and 709 were selected for analysis. Results: 53.1% of the drugs prescribed were non-selective Nonsteroidal Anti-Inflammatory Drugs (NSAIDs). Ibuprofen was formulated in 26.7% of all cases, followed by nimesulide with 24.1% and the combination of acetaminophen plus meloxicam with 10.2%. This same prescription pattern was observed in patients reporting no additional relevant medical history. In the case of gastric history, nimesulide was the drug of choice. 84% of all procedures were surgical extractions of third molars, with ibuprofen 600 mg postoperative for three days as the main therapeutic scheme. Conclusion: ibuprofen, nimesulide, and the combination acetaminophen plus meloxicam were the main analgesics and anti-inflammatory drugs prescribed in this study, according to medical and surgical records.

Therapeutic Uses of Non-Steroidal Anti-Inflammatory Drugs in Dentistry

2001 ◽  
Vol 12 (4) ◽  
pp. 315-330 ◽  
Author(s):  
Raymond A. Dionne ◽  
Charles W. Berthold
Keyword(s):  
Side Effects ◽  
Orofacial Pain ◽  
Oral Surgery ◽  
Chronic Administration ◽  
Therapeutic Uses ◽  
Chronic Orofacial Pain ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
Repeated Dosing ◽  
Dental Applications

The non-steroidal anti-inflammatory drugs (NSAIDs) are among the most widely used classes of drugs for the management of acute and chronic pain in dentistry. Their therapeutic efficacy and toxicity are well-documented and provide evidence that NSAIDs generally provide an acceptable therapeutic ratio of pain relief with fewer adverse effects than the opioid-mild analgesic combination drugs that they have largely replaced for most dental applications. The great many studies done with the oral surgery model of acute pain indicate that a single dose of an NSAID is more effective than combinations of aspirin or acetaminophen plus an opioid, with fewer side-effects, thus making it preferable for ambulatory patients. The combination of an NSAID with an opioid generally results in marginal analgesic activity but with an increased incidence of side-effects, which limits its use to patients in whom the NSAID alone results in inadequate analgesia. The selective COX-2 inhibitors hold promise for clinical efficacy with less toxicity from chronic administration and may prove advantageous for the relief of chronic orofacial pain. The use of repeated doses of NSAIDs for chronic orofacial pain should be re-evaluated in light of a lack of documented efficacy and the potential for serious gastrointestinal and renal toxicity with repeated dosing.

Prevention and Management of Postoperative Pain in Oral Surgery

2018 ◽  
Vol 7 (3) ◽  
pp. 57-63
Author(s):  
Edmund Bailey ◽  
Edmund Bailey
Keyword(s):  
Postoperative Pain ◽  
Adverse Effects ◽  
Oral Surgery ◽  
Evidence Base ◽  
Essential Component ◽  
Post Operative Pain ◽  
Dental Practitioners ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
Adequate Management

Post-operative pain is an area of oral surgery that concerns both patients and practitioners. Adequate management of pain and anxiety in oral surgery is an essential component of any oral surgery service. In this paper, we explore the science behind pain and the drugs available to manage post-operative pain. Discussion is focussed on the analgesics available on the dental practitioners' formulary and the evidence base supporting their use. We explore the beneficial and adverse effects of these analgesics. We also discuss recent controversies relating to non-steroidal anti-inflammatory drugs and opioids. Based on the evidence available, we have developed a protocol to assist practitioners when advising and prescribing analgesics for their patients.

Polyphenols from Cymbopogon citratus inhibit iNOS expression and NO production – a promising source of new anti-inflammatory drugs

Planta Medica ◽  
2010 ◽  
Vol 76 (12) ◽  
Author(s):  
V Francisco ◽  
A Figueirinha ◽  
B Neves ◽  
C Garcia-Rodriguez ◽  
M Lopes ◽  
...  
Keyword(s):  
Inos Expression ◽  
No Production ◽  
Cymbopogon Citratus ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
Promising Source

Heparin and proteoglycans as anti-inflammatory drugs

1996 ◽  
Vol 16 (01) ◽  
pp. 56-59
Author(s):  
D. J. Tyrrell ◽  
C. P. Page
Keyword(s):  
Inflammatory Diseases ◽  
Therapeutic Applications ◽  
Wide Range ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

SummaryEvidence continues to accumulate that the pleiotropic nature of heparin (beyond its anticoagulant potency) includes anti-inflammatory activities at a number of levels. It is clear that drugs exploiting these anti-inflammatory activities of heparin may offer exciting new therapeutic applications to the treatment of a wide range of inflammatory diseases.

Non-Steroidal Anti-inflammatory Drugs (NSAIDs): Synthesis of Ibuprofen, Naproxen and Nabumetone

2019 ◽  
pp. 19-27
Keyword(s):  
Review Paper ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
Synthetic Approaches

This review paper covers the major synthetic approaches attempted towards the synthesis of some Non-Steroidal Anti-Inflammatory Drugs (Naproxen, Ibuprofen and Nabumetone)

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