In Reply: “A nodular growth within a congenital birthmark: Diagnosis of non‐involuting hemangioma is questioned”

2021 ◽  
Vol 38 (3) ◽  
pp. 733-733
Author(s):  
Audrey Chan ◽  
Richard Jahan‐Tigh ◽  
Denise Metry
Keyword(s):  
Nodular Growth

Epithelioid Trophoblastic Tumor: Review of a Rare Neoplasm of the Chorionic-Type Intermediate Trophoblast

2006 ◽  
Vol 130 (12) ◽  
pp. 1875-1877
Author(s):  
Kimberly H. Allison ◽  
Jason E. Love ◽  
Rochelle L. Garcia
Keyword(s):  
Gestational Trophoblastic Disease ◽  
Reproductive Age ◽  
Placental Lactogen ◽  
Variable Expression ◽  
Trophoblastic Tumor ◽  
Trophoblastic Cells ◽  
Epithelioid Trophoblastic Tumor ◽  
Positive Immunostaining ◽  
Nodular Growth ◽  
Type Intermediate

Abstract We present a brief review of epithelioid trophoblastic tumor, a rare trophoblastic neoplasm derived from chorionic-type intermediate trophoblastic cells that typically presents in reproductive-age women between 1 and 18 years following a previous gestation. Histologic features include a nodular growth pattern of monomorphic, epithelioid cells within a hyaline matrix. Areas of necrosis and mitotic activity (0–9 mitoses per 10 high-power fields) are additional features of this neoplasm. Positive immunostaining for p63 and cytokeratin, frequent location in the lower uterine segment and endocervix, as well as the epithelioid appearance can lead to confusion with squamous cell carcinoma. Inhibin-α is typically expressed, as well as focal, more variable expression of other trophoblastic markers including β-human chorionic gonadotropin, human placental lactogen, placental alkaline phosphate, and Mel-CAM (CD148). The clinical behavior of this rare form of gestational trophoblastic disease is difficult to predict. Although most cases follow a benign course following resection, there is a potential for metastatic disease.

Intraductal papillary mucinous neoplasm (IPMN) of the gastric-type with focal nodular growth of the arborizing papillae: a case of high-grade transformation of the gastric-type IPMN

2006 ◽  
Vol 449 (1) ◽  
pp. 112-116 ◽  
Author(s):  
Shinichi Ban ◽  
Yoshihisa Naitoh ◽  
Fumihiro Ogawa ◽  
Yoshihiko Shimizu ◽  
Michio Shimizu ◽  
...  
Keyword(s):  
Intraductal Papillary Mucinous Neoplasm ◽  
High Grade ◽  
Mucinous Neoplasm ◽  
Gastric Type ◽  
Nodular Growth ◽  
High Grade Transformation

scholarly journals Follicular lymphoid hyperplasia of the posterior maxillary site presenting as uncommon entity: a case report and review of the literature

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Masato Watanabe ◽  
Ai Enomoto ◽  
Yuya Yoneyama ◽  
Michihide Kohno ◽  
On Hasegawa ◽  
...  
Keyword(s):  
Lymphoid Hyperplasia ◽  
Germinal Centers ◽  
Resected Specimen ◽  
Unusual Site ◽  
Case Presentation ◽  
Lymphoid Follicles ◽  
Complete Surgical Resection ◽  
Left Posterior ◽  
Nodular Growth ◽  
Oral And Maxillofacial Region

Abstract Background Follicular lymphoid hyperplasia (FLH) is characterized by an increased number and size of lymphoid follicles. In some cases, the etiology of FLH is unclear. FLH in the oral and maxillofacial region is an uncommon benign entity which may resemble malignant lymphoma clinically and histologically. Case presentation We report the case of a 51-year-old woman who presented with an asymptomatic firm mass in the left posterior maxillary site. Computed tomography scan of her head and neck showed a clear circumscribed solid mass measuring 28 × 23 mm in size. There was no evidence of bone involvement. Incisional biopsy demonstrated benign lymphoid tissue. The patient underwent complete surgical resection. Histologically, the resected specimen showed scattered lymphoid follicles with germinal centers and predominant small lymphocytes in the interfollicular areas. Immunohistochemically, the lymphoid follicles were positive for CD20, CD79a, CD10, CD21, and Bcl6. The germinal centers were negative for Bcl2. Based on these findings, a diagnosis of benign FLH was made. There was no recurrence at 1 year postoperatively. Conclusions We diagnosed an extremely rare case of FLH arising from an unusual site and whose onset of entity is unknown. Careful clinical and histopathological evaluations are essential in making a differential diagnosis from a neoplastic lymphoid proliferation with a nodular growth pattern.

Histologic and Immunohistochemical Characterization of Hemangiomas in the Skin of Seven Young Horses

1996 ◽  
Vol 33 (2) ◽  
pp. 142-149 ◽  
Author(s):  
G. C. Johnson ◽  
M. A. Miller ◽  
J. L. Floss ◽  
J. R. Turk
Keyword(s):  
Smooth Muscle Actin ◽  
Vascular Tumors ◽  
Vascular Endothelial ◽  
Vascular Walls ◽  
Vascular Neoplasms ◽  
Innermost Layer ◽  
Nodular Growth ◽  
Young Horses ◽  
Time Of Presentation

The histologic and immunochemical characteristics of benign vascular tumors excised from the skin of seven young horses were evaluated. The patients were male horses of various breeds and were 16 months of age or younger at the time of presentation. Six tumors occurred on the extremities, and one was removed from the lip. Histologically, most tumors consisted of cellular nodules of varying compactness with few to many blood-filled lumina. Nodular growth separated preexisting adnexa and subcutaneous collagen. Some tumors contained or consisted predominantly of loosely packed arrays of ramifying arteries, veins, and capillaries separated by collagen within the dermis and subcutis. Within areas of nodular growth, multilayered vascular walls were encircled by reticulin strands that surrounded the endothelium and adjacent pericytes and also separated nonperivascular cells in the mass. Immunohistochemical staining of factor-VIII-related antigen and labeling by Ulex europeus-1 lectin was restricted to an innermost layer of cells surrounding vascular spaces, confirming their vascular endothelial origin. The plump fusiform cells arranged concentrically around the endothelium and some of those unassociated with vascular lumina stained with antibody to α-smooth muscle actin, as did the muscularis of larger vessels inside and outside of tumor nodules. These findings demonstrate an orderly arrangement between endothelium and supportive cells in these benign vascular neoplasms of young horses, similar to that observed during vascular development.

scholarly journals A Rare Presentation of Nodular Growth over Right Anterior Chest Wall in an Elderly Male Mimicking Carcinoma Breast

JMS SKIMS ◽  
2010 ◽  
Vol 13 (2) ◽  
pp. 70-71
Author(s):  
R K Maurya ◽  
Pawan Kumar Singh ◽  
Vivek Garg
Keyword(s):  
Breast Carcinoma ◽  
Chest Wall ◽  
Anterior Chest Wall ◽  
Elderly Male ◽  
Rare Presentation ◽  
Carcinoma Breast ◽  
Nodular Growth

Malignant malenoma in chest wall are rare, although reported. We hereby report a 60 year male who presented with nodular growth over anterior chest wall mimicking breast carcinoma. JMS 2010;13(2):70-71

Prolonged Metformin intake is associated with decreased thyroid nodular growth in obese

2020 ◽  
Author(s):  
Maxim Lushchyk ◽  
Artur Grigorovich ◽  
Hanna Tuzava ◽  
Maxim Ameliyanovich ◽  
Irma Mosse ◽  
...  
Keyword(s):  
Nodular Growth

An infiltrated and a nodular growth arising on the face

2012 ◽  
Vol 37 (7) ◽  
pp. 814-816
Author(s):  
A. J. Wright ◽  
N. R. Farquharson ◽  
M. S. Fernando ◽  
S. E. Cockayne
Keyword(s):  
The Face ◽  
Nodular Growth

930. Nodular growth in thick-sputtered metallic coatings

Vacuum ◽  
1975 ◽  
Vol 25 (6) ◽  
pp. 290
Keyword(s):  
Metallic Coatings ◽  
Nodular Growth

scholarly journals Dealloying of gold–copper alloy nanowires: From hillocks to ring-shaped nanopores

2016 ◽  
Vol 7 ◽  
pp. 1361-1367 ◽  
Author(s):  
Adrien Chauvin ◽  
Cyril Delacôte ◽  
Mohammed Boujtita ◽  
Benoit Angleraud ◽  
Junjun Ding ◽  
...  
Keyword(s):  
Copper Alloy ◽  
Surface Defects ◽  
Complex Surface ◽  
Metal Nanowires ◽  
Gold Nanowires ◽  
Porous Gold ◽  
Gold Silver ◽  
Nodular Growth ◽  
Alloy Nanowires ◽  
High Roughness

We report on a novel fabrication approach of metal nanowires with complex surface. Taking advantage of nodular growth triggered by the presence of surface defects created intentionally on the substrate as well as the high tilt angle between the magnetron source axis and the normal to the substrate, metal nanowires containing hillocks emerging out of the surface can be created. The approach is demonstrated for several metals and alloys including gold, copper, silver, gold–copper and gold–silver. We demonstrate that applying an electrochemical dealloying process to the gold–copper alloy nanowire arrays allows for transforming the hillocks into ring-like shaped nanopores. The resulting porous gold nanowires exhibit a very high roughness and high specific surface making of them a promising candidate for the development of SERS-based sensors.

Long-term follow-up of Dupuytren disease after injection of triamcinolone acetonide in Chinese patients in Taiwan

2017 ◽  
Vol 42 (7) ◽  
pp. 678-682 ◽  
Author(s):  
C.-Y. Yin ◽  
H.-H. M. Yu ◽  
J.-P. Wang ◽  
Y.-C. Huang ◽  
T.-F. Huang ◽  
...  
Keyword(s):  
Triamcinolone Acetonide ◽  
Ultrasound Examination ◽  
Early Stage ◽  
Chinese Patients ◽  
Level Of Evidence ◽  
Long Term Follow Up ◽  
Nodular Growth ◽  
Dupuytren Disease

Injection of triamcinolone acetonide is a non-operative treatment for early-stage Dupuytren disease in Caucasians, but its effectiveness in non-Caucasians is unclear. We report averaged 5-year follow-up results of 37 patients (49 affected hands) with early-stage Dupuytren disease for patients in Taiwan (non-Caucasian) who received a single dose of 5 mg triamcinolone acetonide injection into nodules monthly for 3 months. Using ultrasound, we recorded no progression of sizes of the modules following injection after 6 months. After an average 5-year follow-up, two patients with three hands (6%) experienced reactivation of the treated nodules. None required surgical intervention. Ultrasound examination showed that sizes of the treated Dupuytren nodules decreased significantly by 40% 6 months after injection and 56% at the final follow-up. We conclude that in these Chinese patients in Taiwan with early Dupuytren nodules, triamcinolone acetonide injection was effective in reducing the size of the Dupuytren nodules and maintaining long-term durable control of the nodular growth. Level of evidence: III

Sign in / Sign up

Export Citation Format

Share Document