scholarly journals Seasonal Influenza Vaccination during Pregnancy and the Risks of Preterm Delivery and Small for Gestational Age Birth

2014 ◽  
Vol 28 (6) ◽  
pp. 498-509 ◽  
Author(s):  
Katherine A. Ahrens ◽  
Carol Louik ◽  
Stephen Kerr ◽  
Allen A. Mitchell ◽  
Martha M. Werler
Keyword(s):  
Influenza Vaccination ◽  
Preterm Delivery ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Seasonal Influenza ◽  
Seasonal Influenza Vaccination

scholarly journals AB0372 PREGNANCY OUTCOME IN WOMEN WITH SJÖGREN SYNDROME IS OFTEN COMPLICATED BY PLACENTA INSUFFICIENCY

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1486.2-1486
Author(s):  
I. Troester ◽  
F. Kollert ◽  
A. Zbinden ◽  
L. Raio ◽  
F. Foerger
Keyword(s):  
Pregnancy Outcome ◽  
Preterm Delivery ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Low Dose ◽  
Sjögren Syndrome ◽  
Sjogren Syndrome ◽  
Live Births ◽  
Dose Aspirin ◽  
Low Dose Aspirin

Background:Chronic inflammatory rheumatic diseases are often associated with a negative effect on pregnancy outcome. Most obstetrical complications are placenta-mediated such as preterm delivery and growths restrictions. In women with Sjögren syndrome, data on placenta- mediated complications are scarce and conflicting (1,2).Objectives:To analyse neonatal outcome in women with Sjögren syndrome with focus on preterm delivery and growth restriction.Methods:We retrospectively analysed 23 pregnancies of 16 patients with Sjögren syndrome that were followed at our centre with regard to pregnancy outcome, medication and disease characteristics. Small for gestational age was defined as birthweight percentile <10th. Preterm delivery was defined as delivery before 37, early term as delivery between 37-39 and term as delivery between 39-42 weeks of gestation.Results:Of 23 pregnancies, one ended in a miscarriage and 22 resulted in live births including one set of twins. Treatment used during pregnancy was hydroxychloroquine (20 pregnancies), prednisone (8), azathioprine (5) and cyclosporine (2). Concomitant treatment with low-dose aspirin was used in 9 pregnancies.Of the 22 live births, 17 were born at early term and 5 at term. There were no preterm deliveries. Median birth weight was 2820g (range 2095-3845g). Nine newborns (40.9%) were small for gestational age (SGA). Maternal treatment during these pregnancies was hydroxychloroquine in all cases and additional low-dose aspirin in three cases. Elevated CRP levels during pregnancy were found in 57% of the cases with SGA outcome. Only one woman with an SGA infant had positive anti-phospholipid antibodies.Regarding delivery mode, most patients had caesarean sections.Conclusion:In our cohort of women with Sjögren syndrome the prevalence of small for gestational age infants was high despite maternal treatment with hydroxychloroquine. Inflammatory markers could help to identify the patients at risk for placental insufficiency, yet prospective studies of larger cohorts are needed.References:[1]Gupta S et al; Sjögren Syndrome and Pregnancy: A literature review. Perm J 2017; 21:16-047[2]De Carolis S et al; The impact of primary Sjögren’s syndrome on pregnancy outcome: Our series and review of the literature. Autoimmun Rev 2014; 13(2):103-7Disclosure of Interests:Isabella Troester: None declared, Florian Kollert Employee of: Novartis, Astrid Zbinden: None declared, Luigi Raio: None declared, Frauke Foerger Grant/research support from: unrestricted grant from UCB, Consultant of: UCB, GSK, Roche, Speakers bureau: UCB, GSK

scholarly journals Impact of national influenza vaccination strategy in severe influenza outcomes among the high-risk Portuguese population

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Ausenda Machado ◽  
Irina Kislaya ◽  
Amparo Larrauri ◽  
Carlos Matias Dias ◽  
Baltazar Nunes
Keyword(s):  
High Risk ◽  
Influenza Vaccination ◽  
Seasonal Influenza ◽  
Vaccine Coverage ◽  
Vaccination Strategy ◽  
High Risk Population ◽  
Risk Population ◽  
Seasonal Influenza Vaccination ◽  
Severe Influenza ◽  
The Impact

Abstract Background All aged individuals with a chronic condition and those with 65 and more years are at increased risk of severe influenza post-infection complications. There is limited research on cases averted by the yearly vaccination programs in high-risk individuals. The objective was to estimate the impact of trivalent seasonal influenza vaccination on averted hospitalizations and death among the high-risk population in Portugal. Methods The impact of trivalent seasonal influenza vaccination was estimated using vaccine coverage, vaccine effectiveness and the number of influenza-related hospitalizations and deaths. The number of averted events (NAE), prevented fraction (PF) and number needed to vaccinate (NVN) were estimated for seasons 2014/15 to 2016/17. Results The vaccination strategy averted on average approximately 1833 hospitalizations and 383 deaths per season. Highest NAE was observed in the ≥65 years population (85% of hospitalizations and 95% deaths) and in the 2016/17 season (1957 hospitalizations and 439 deaths). On average, seasonal vaccination prevented 21% of hospitalizations in the population aged 65 and more, and 18.5% in the population with chronic conditions. The vaccination also prevented 29% and 19.5% of deaths in each group of the high-risk population. It would be needed to vaccinate 3360 high-risk individuals, to prevent one hospitalization and 60,471 high-risk individuals to prevent one death. Conclusion The yearly influenza vaccination campaigns had a sustained positive benefit for the high-risk population, reducing hospitalizations and deaths. These results can support public health plans toward increased vaccine coverage in high-risk groups.

scholarly journals Seasonal influenza vaccination coverage and its determinants among nursing homes personnel in western France

2017 ◽  
Vol 17 (1) ◽  
Author(s):  
Christelle Elias ◽  
Anna Fournier ◽  
Anca Vasiliu ◽  
Nicolas Beix ◽  
Rémi Demillac ◽  
...  
Keyword(s):  
Nursing Homes ◽  
Influenza Vaccination ◽  
Vaccination Coverage ◽  
Seasonal Influenza ◽  
Seasonal Influenza Vaccination

scholarly journals Support for Seasonal Influenza Vaccination Requirements among US Healthcare Personnel

2012 ◽  
Vol 33 (3) ◽  
pp. 213-221 ◽  
Author(s):  
Jürgen Maurer ◽  
Katharine M. Harris ◽  
Carla L. Black ◽  
Gary L. Euler
Keyword(s):  
Influenza Vaccination ◽  
Seasonal Influenza ◽  
Safety Issue ◽  
Healthcare Personnel ◽  
Sampling Frame ◽  
Staff Support ◽  
Term Care ◽  
Seasonal Influenza Vaccination ◽  
Care Facilities ◽  
Serious Disease

Objective.To measure support for seasonal influenza vaccination requirements among US healthcare personnel (HCP) and its associations with attitudes regarding influenza and influenza vaccination and self-reported coverage by existing vaccination requirements.Design.Between lune 1 and June 30, 2010, we surveyed a sample of US HCP (n = 1,664) recruited using an existing probability-based online research panel of participants representing the US general population as a sampling frame.Setting.General community.Participants.Eligible HCP who (1) reported having worked as medical doctors, health technologists, healthcare support staff, or other health practitioners or who (2) reported having worked in hospitals, ambulatory care facilities, long-term care facilities, or other health-related settings.Methods.We analyzed support for seasonal influenza vaccination requirements for HCP using proportion estimation and multivariable probit models.Results.A total of 57.4% (95% confidence interval, 53.3%–61.5%) of US HCP agreed that HCP should be required to be vaccinated for seasonal influenza. Support for mandatory vaccination was statistically significantly higher among HCP who were subject to employer-based influenza vaccination requirements, who considered influenza to be a serious disease, and who agreed that influenza vaccine was safe and effective.Conclusions.A majority of HCP support influenza vaccination requirements. Moreover, providing HCP with information about the safety of influenza vaccination and communicating that immunization of HCP is a patient safety issue may be important for generating staff support for influenza vaccination requirements.Infect Control Hosp Epidemiol 2012;33(3):213-221

scholarly journals Parent-Reported Intention to Vaccinate Children Against COVID-19: Influences of COVID-19 and Seasonal Influenza Vaccination

2021 ◽  
pp. 000992282110464
Author(s):  
Ashley V. Hill ◽  
Krissy Moehling Geffel ◽  
Daniel R. Lavage ◽  
Alysia Davis ◽  
Namita Dwarakanath ◽  
...  
Keyword(s):  
Influenza Vaccination ◽  
Seasonal Influenza ◽  
Seasonal Influenza Vaccination
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