scholarly journals Incidence of Mood or Anxiety Disorders in Children of Parents with Multiple Sclerosis

2016 ◽  
Vol 30 (4) ◽  
pp. 356-366 ◽  
Author(s):  
Neda Razaz ◽  
Helen Tremlett ◽  
Thomas Boyce ◽  
Martin Guhn ◽  
Ruth Ann Marrie ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Anxiety Disorders

Prevalence of psychiatric disorders among patients with Multiple Sclerosis: a cross-sectional study.

2020 ◽  
Author(s):  
Michał Błachut ◽  
Anna Rebeka Szczegielniak ◽  
Krzysztof Świerzy ◽  
Magdalena Zając- Tarska ◽  
Katarzyna Kubicka-Bączyk ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Mental Disorders ◽  
Anxiety Disorders ◽  
Psychiatric Disorders ◽  
Underlying Disease ◽  
Psychiatric Evaluation ◽  
Cross Sectional ◽  
Mini International Neuropsychiatric Interview ◽  
Sociodemographic Data ◽  
Number Of Patients

Abstract Background: Multiple Sclerosis is one of the leading autoimmune disorders causing disability among young adults. Various types of mood, affect, and behaviour disorders along with cognitive impairment can be manifested in a course of MS, with affective and anxiety disorders being the most prevalent. Mental health challenges, in addition to the neurological burden of MS, significantly affect quality of life and the course of the underlying disease. Objective: The aim of this work was to determine the prevalence of mental disorders in a sample of MS patients during outpatient treatment in Zabrze, Poland, with a focus on those with mood and anxiety disorders, and to compare the results obtained in these groups with clinical and sociodemographic data. Method: The study was conducted between 2017 and 2018 on 103 MS patients of the Neurological Outpatient Clinic of the Medical University of Silesia Hospital No.1 in Zabrze, Poland. During the study, sociodemographic data were collected, as well as the type and course of the underlying disease, comorbidities, and medicines used. The MINI-international neuropsychiatric interview and a psychiatric examination were utilized to assess the occurrence of mental disorders. Result: 68% of all patients received a psychiatric diagnosis at some point in their life with only 4% having been hospitalized before; 49.5% met the diagnostic criteria for various psychiatric disorders. Measured by the MINI International Neuropsychiatric Interview, 33% of patients reported a past episode of major depression while 8.7% met the criteria for a current episode. The same number of patients admitted ongoing treatment due to recurrent depressive disorder. In regards to anxiety disorders, the most common was generalized anxiety disorder (10.7%), followed by agoraphobia (8.7%), panic disorder (7.8%), and social phobia (4.9%). Most of the patients (94.2%) at the time of the psychiatric evaluation presented a low level of suicide risk, while 1.9% of the patients presented a medium risk, and 3.9% - a high risk. Conclusion(s): The study confirmed a significantly higher prevalence of mental disorders among MS patients; thus, the psychiatric state of patients in this group should be investigated systematically, simultaneously with the assessment of their neurological state. Trial registration: N/A Key words: Multiple Sclerosis, psychiatric disorders, comorbidity, psychiatric care, clinical characteristics.

scholarly journals Effect of mood and anxiety disorders on health care utilization in multiple sclerosis

2020 ◽  
pp. 135245852096388
Author(s):  
Ruth Ann Marrie ◽  
Randy Walld ◽  
James M Bolton ◽  
Jitender Sareen ◽  
Scott B Patten ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Health Care ◽  
Anxiety Disorders ◽  
Health Care Utilization ◽  
Care Utilization ◽  
Health Services Use ◽  
Physician Visits ◽  
Mood And Anxiety Disorders ◽  
Drug Classes ◽  
Hospital Days

Background: Little is known about the effects of changes in the presence or absence of psychiatric disorders on health care utilization in multiple sclerosis (MS). Objective: To evaluate the association between “active” mood and anxiety disorders (MAD) and health care utilization in MS. Methods: Using administrative data from Manitoba, Canada, we identified 4748 persons with MS and 24,154 persons without MS matched on sex, birth year, and region. Using multivariable general linear models, we evaluated the within-person and between-person effects of any “active” MAD on annual physician visits, hospital days, and number of drug classes dispensed in the following year. Results: Annually, the MS cohort had an additional two physician visits, two drug classes, and nearly two more hospital days versus the matched cohort. Individuals with any MAD had more physician visits, had hospital days, and used more drug classes than individuals without a MAD. Within individuals, having an “active” MAD was associated with more utilization for all outcomes than not having an “active” MAD, but the magnitude of this effect was much smaller for visits and drugs than the between-person effect. Conclusion: Within individuals with MS, changes in MAD activity are associated with changes in health services use.

scholarly journals The validity and reliability of screening measures for depression and anxiety disorders in multiple sclerosis

2018 ◽  
Vol 20 ◽  
pp. 9-15 ◽  
Author(s):  
Ruth Ann Marrie ◽  
Lixia Zhang ◽  
Lisa M. Lix ◽  
Lesley A. Graff ◽  
John R. Walker ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Anxiety Disorders ◽  
Depression And Anxiety ◽  
Validity And Reliability ◽  
Screening Measures

scholarly journals Comorbid anxiety disorders and treatment of depression in people with multiple sclerosis.

2010 ◽  
Vol 55 (3) ◽  
pp. 255-262 ◽  
Author(s):  
Michelle Nicole Burns ◽  
Juned Siddique ◽  
J. Konadu Fokuo ◽  
David C. Mohr
Keyword(s):  
Multiple Sclerosis ◽  
Anxiety Disorders ◽  
Comorbid Anxiety ◽  
Treatment Of Depression

Anxiety disorders and their clinical correlates in multiple sclerosis patients

2007 ◽  
Vol 13 (1) ◽  
pp. 67-72 ◽  
Author(s):  
M Korostil ◽  
A Feinstein
Keyword(s):  
Multiple Sclerosis ◽  
Anxiety Disorder ◽  
Anxiety Disorders ◽  
Social Stress ◽  
Function Analysis ◽  
Depression Scale ◽  
Self Report ◽  
Compulsive Disorder ◽  
Clinical Correlates ◽  
Multiple Sclerosis Patients

Objective To assess prevalence rates and clinical correlates of anxiety disorders in patients with multiple sclerosis (MS). Methods Demographic and neurological data were collected on 140 consecutive clinic attendees, and their lifetime and point prevalences of anxiety disorders were determined with the Structured Clinical Interview for DSM-IV disorders (SCID-IV). All subjects completed the self-report Hospital Anxiety and Depression Scale (HADS). Suicidal intent was rated with the Beck Suicide Scale (BSS), psychosocial stressors and supports were quantified with Social Stress and Support Interview (SSSI), and cognition assessed with Neuropsychological Screening Battery for MS. Results The lifetime prevalence of any anxiety disorder was 35.7%, with panic disorder (10%), obsessive compulsive disorder (8.6%), and generalized anxiety disorder (18.6%), the most common diagnoses obtained. Subjects with an anxiety disorder were more likely to be female, have a history of depression, drink to excess, report higher social stress and have contemplated suicide. The diagnosis of an anxiety disorder had been missed in the majority of subjects, therefore, they had not received treatment. A discriminant function analysis identified a series of variables that correctly classified 75% of patients with an anxiety disorder. Conclusion Anxiety disorders are common in patients with MS, but are frequently overlooked and under-treated. Risk factors include being female, a co-morbid diagnosis of depression, and limited social support. Clinicians should evaluate all MS subjects for anxiety disorders, as they represent a treatable cause of disability in MS.

P-398 - Comparison of two clinical cases of anxiety disorders and depression in multiple sclerosis (MS)

2012 ◽  
Vol 27 ◽  
pp. 1
Author(s):  
A. Bednarz ◽  
K. Kosteczko ◽  
K. Krysta ◽  
I. Krupka-Matuszczyk
Keyword(s):  
Multiple Sclerosis ◽  
Anxiety Disorders ◽  
Clinical Cases

Validation of the Hospital Anxiety and Depression Scale for use with multiple sclerosis patients

2009 ◽  
Vol 15 (12) ◽  
pp. 1518-1524 ◽  
Author(s):  
Kimia Honarmand ◽  
Anthony Feinstein
Keyword(s):  
Multiple Sclerosis ◽  
Major Depression ◽  
Anxiety Disorders ◽  
Depression Scale ◽  
Area Under The Curve ◽  
Anxiety And Depression ◽  
Hospital Anxiety ◽  
Dsm Iv ◽  
Roc Area ◽  
Multiple Sclerosis Patients

Detecting clinically significant symptoms of depression and anxiety in medically ill patients using self-report rating scales presents a challenge because of somatic confounders. The Hospital Anxiety and Depression Scale (HADS) was developed with this in mind, but has never been validated for a multiple sclerosis population. Our objective was to validate the HADS for multiple sclerosis patients. Multiple sclerosis patients were interviewed for the presence of major depression ( n = 180) and anxiety disorders ( n = 140) with the Structured Clinical Interview for DSM-IV disorders. A receiver operating characteristic (ROC) analysis was undertaken to assess which HADS cut-off scores give the best yield with respect to diagnoses of major depression and all anxiety disorders defined by the Structured Clinical Interview for DSM-IV. A threshold score of 8 or greater on the HADS depression subscale provides a sensitivity of 90% and specificity of 87.3% (ROC area under the curve 0.938). The same cut-off score gives a sensitivity of 88.5% and a specificity of 80.7% on the anxiety subscale (ROC area under the curve 0.913), but for generalized anxiety disorder only. The study confirms the usefulness of the HADS as a marker of major depression and generalized anxiety disorder, but not other anxiety disorders, in multiple sclerosis patients.

scholarly journals High prevalence of comorbidities at diagnosis in immigrants with multiple sclerosis

2021 ◽  
pp. 135245852110317
Author(s):  
Dalia Rotstein ◽  
Colleen Maxwell ◽  
Karen Tu ◽  
Jodi Gatley ◽  
Priscila Pequeno ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Anxiety Disorders ◽  
Chronic Obstructive ◽  
Healthy Immigrant Effect ◽  
Obstructive Pulmonary Disease ◽  
Health Administrative Data ◽  
High Prevalence ◽  
Inflammatory Bowel ◽  
Immigrant Effect

Background: Multiple sclerosis (MS) has been associated with certain comorbidities in general population studies, but it is unknown how comorbidity may affect immigrants with MS. Objective: To compare prevalence of comorbidities in immigrants and long-term residents at MS diagnosis, and in matched control populations without MS. Methods: We identified incident MS cases using a validated definition applied to health administrative data in Ontario, Canada, from 1994 to 2017, and categorized them as immigrants or long-term residents. Immigrants and long-term residents without MS (controls) were matched to MS cases 3:1 on sex, age, and geography. Results: There were 1534 immigrants and 23,731 long-term residents with MS matched with 4585 and 71,193 controls, respectively. Chronic obstructive pulmonary disease (COPD), diabetes, hypertension, ischemic heart disease, migraine, epilepsy, mood/anxiety disorders, schizophrenia, inflammatory bowel disease (IBD), and rheumatoid arthritis were significantly more prevalent among immigrants with MS compared to their controls. Prevalence of these conditions was generally similar comparing immigrants to long-term residents with MS, although COPD, epilepsy, IBD, and mood/anxiety disorders were less prevalent in immigrants. Conclusion: Immigrants have a high prevalence of multiple comorbidities at MS diagnosis despite the “healthy immigrant effect.” Clinicians should pay close attention to identification and management of comorbidity in immigrants with MS.

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