Maternal Obesity and Male Genital Anomalies: Potential Role of Placental Insufficiency and Metabolic Syndrome

2017 ◽  
Vol 31 (5) ◽  
pp. e1-e3 ◽  
Author(s):  
Francisco J. Schneuer ◽  
Natasha Nassar
Keyword(s):  
Metabolic Syndrome ◽  
Potential Role ◽  
Maternal Obesity ◽  
Placental Insufficiency ◽  
Male Genital

The Potential Role of Antioxidants in Metabolic Syndrome

2016 ◽  
Vol 22 (7) ◽  
pp. 859-869 ◽  
Author(s):  
Bianca Martins Gregório ◽  
Diogo Benchimol De Souza ◽  
Fernanda Amorim de Morais Nascimento ◽  
Leonardo Matta ◽  
Caroline Fernandes-Santos
Keyword(s):  
Metabolic Syndrome ◽  
Potential Role

scholarly journals Potential role of circulating microRNAs (486-5p, 497, 509-5p and 605) in metabolic syndrome Egyptian male patients

2019 ◽  
Vol Volume 12 ◽  
pp. 601-611 ◽  
Author(s):  
Mohamed Bakr Zaki ◽  
Ahmed Ibrahim Abulsoud ◽  
Ahmed Mohamed Elsisi ◽  
Ahmed Soliman Doghish ◽  
Ossama Abd Elmotaal Mansour ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Potential Role ◽  
Circulating Micrornas ◽  
Male Patients

Potential role of taurine in the prevention of diabetes and metabolic syndrome

Amino Acids ◽  
2012 ◽  
Vol 46 (1) ◽  
pp. 81-88 ◽  
Author(s):  
Masato Imae ◽  
Toshiki Asano ◽  
Shigeru Murakami
Keyword(s):  
Metabolic Syndrome ◽  
Potential Role ◽  
Prevention Of Diabetes

scholarly journals Effects of Maternal Obesity On Placental Phenotype

2020 ◽  
Vol 19 (2) ◽  
pp. 113-131 ◽  
Author(s):  
A.L. Fowden ◽  
E.J. Camm ◽  
A.N. Sferruzzi-Perri
Keyword(s):  
Potential Role ◽  
Maternal Obesity ◽  
Endocrine Function ◽  
Obstetric Outcomes ◽  
Contributory Factor ◽  
Intrauterine Development ◽  
Maternal Undernutrition ◽  
Clinical Complications ◽  
Adverse Impacts

: The incidence of obesity is rising rapidly worldwide with the consequence that more women are entering pregnancy overweight or obese. This leads to an increased incidence of clinical complications during pregnancy and of poor obstetric outcomes. The offspring of obese pregnancies are often macrosomic at birth although there is also a subset of the progeny that are growth-restricted at term. Maternal obesity during pregnancy is also associated with cardiovascular, metabolic and endocrine dysfunction in the offspring later in life. As the interface between the mother and fetus, the placenta has a central role in programming intrauterine development and is known to adapt its phenotype in response to environmental conditions such as maternal undernutrition and hypoxia. However, less is known about placental function in the abnormal metabolic and endocrine environment associated with maternal obesity during pregnancy. This review discusses the placental consequences of maternal obesity induced either naturally or experimentally by increasing maternal nutritional intake and/or changing the dietary composition. It takes a comparative, multi-species approach and focusses on placental size, morphology, nutrient transport, metabolism and endocrine function during the later stages of obese pregnancy. It also examines the interventions that have been made during pregnancy in an attempt to alleviate the more adverse impacts of maternal obesity on placental phenotype. The review highlights the potential role of adaptations in placental phenotype as a contributory factor to the pregnancy complications and changes in fetal growth and development that are associated with maternal obesity.

The potential role of the intestinal gut microbiota in obesity and the metabolic syndrome

2009 ◽  
Vol 5 (7) ◽  
pp. 71-92 ◽  
Author(s):  
Francesca Fava ◽  
Julie A. Lovegrove ◽  
Kieran M. Tuohy ◽  
Glenn R. Gibson
Keyword(s):  
Metabolic Syndrome ◽  
Gut Microbiota ◽  
Potential Role ◽  
The Metabolic Syndrome

scholarly journals The potential role of betatrophin in hepatocellular carcinoma and metabolic syndrome

2019 ◽  
Vol 1146 ◽  
pp. 012003 ◽  
Author(s):  
H Susanto ◽  
A Aulanni’am ◽  
C H Wang ◽  
D K Wuragil ◽  
A Y Handaya ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Metabolic Syndrome ◽  
Potential Role

scholarly journals Maternal obesity and stillbirth at term; placental pathology—A case control study

PLoS ONE ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. e0250983
Author(s):  
Hanna Åmark ◽  
Magnus Westgren ◽  
Meeli Sirotkina ◽  
Ingela Hulthén Varli ◽  
Martina Persson ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Potential Role ◽  
Maternal Obesity ◽  
Case Control Study ◽  
Case Control ◽  
Normal Weight ◽  
Obese Women ◽  
Control Study ◽  
Velamentous Cord Insertion

Objective The aim was to explore the potential role of the placenta for the risk of stillbirth at term in pregnancies of obese women. Methods This was a case-control study comparing placental findings from term stillbirths with placental findings from live born infants. Cases were singleton term stillbirths to normal weight or obese women, identified in the Stockholm stillbirth database, n = 264 and n = 87, respectively. Controls were term singletons born alive to normal weight or obese women, delivered between 2002–2005 and between 2018–2019. Placentas were compared between women with stillborn and live-born infants, using logistic regression analyses. Results A long and hyper coiled cord, cord thrombosis and velamentous cord insertion were stronger risk factors for stillbirth in obese women compared to normal weight women. When these variables were adjusted for in the logistic regression analysis, also adjusted for potential confounders, the odds ratio for stillbirth in obese women decreased from 1.89 (CI 1.24–2.89) to 1.63 (CI 1.04–2.56). Conclusion Approximately one fourth of the effect of obesity on the risk of stillbirth in term pregnancies is explained by umbilical cord associated pathology.

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