scholarly journals Maternal obesity and stillbirth at term; placental pathology—A case control study

PLoS ONE ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. e0250983
Author(s):  
Hanna Åmark ◽  
Magnus Westgren ◽  
Meeli Sirotkina ◽  
Ingela Hulthén Varli ◽  
Martina Persson ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Potential Role ◽  
Maternal Obesity ◽  
Case Control Study ◽  
Case Control ◽  
Normal Weight ◽  
Obese Women ◽  
Control Study ◽  
Velamentous Cord Insertion

Objective The aim was to explore the potential role of the placenta for the risk of stillbirth at term in pregnancies of obese women. Methods This was a case-control study comparing placental findings from term stillbirths with placental findings from live born infants. Cases were singleton term stillbirths to normal weight or obese women, identified in the Stockholm stillbirth database, n = 264 and n = 87, respectively. Controls were term singletons born alive to normal weight or obese women, delivered between 2002–2005 and between 2018–2019. Placentas were compared between women with stillborn and live-born infants, using logistic regression analyses. Results A long and hyper coiled cord, cord thrombosis and velamentous cord insertion were stronger risk factors for stillbirth in obese women compared to normal weight women. When these variables were adjusted for in the logistic regression analysis, also adjusted for potential confounders, the odds ratio for stillbirth in obese women decreased from 1.89 (CI 1.24–2.89) to 1.63 (CI 1.04–2.56). Conclusion Approximately one fourth of the effect of obesity on the risk of stillbirth in term pregnancies is explained by umbilical cord associated pathology.

scholarly journals Potential Role of Vegetarianism on Nutritional and Cardiovascular Status in Taiwanese Dialysis Patients: A Case-Control Study

PLoS ONE ◽  
2016 ◽  
Vol 11 (6) ◽  
pp. e0156297 ◽  
Author(s):  
Shih-Hsiang Ou ◽  
Mei-Yin Chen ◽  
Chien-Wei Huang ◽  
Nai-Ching Chen ◽  
Chien-Hsing Wu ◽  
...  
Keyword(s):  
Potential Role ◽  
Case Control Study ◽  
Case Control ◽  
Dialysis Patients ◽  
Control Study

scholarly journals Is body mass index associated with the incidence of endometriosis and the severity of dysmenorrhoea: a case–control study in China?

BMJ Open ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. e037095
Author(s):  
Yunhui Tang ◽  
Mingzhi Zhao ◽  
Luling Lin ◽  
Yifei Gao ◽  
George Qiaoqi Chen ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Risk Factor ◽  
Body Mass ◽  
Case Control Study ◽  
Case Control ◽  
Normal Weight ◽  
Reproductive Age ◽  
Obese Patients ◽  
Obese Women ◽  
Control Study

ObjectiveEndometriosis is considered as a serious gynaecological disease in women at a reproductive age. Lower body mass index (BMI) is thought to be a risk factor. However, recent studies indicated that women with normal BMI were also more likely to develop endometriosis, suggesting the association with BMI is controversial. We therefore investigated the association of BMI and surgically diagnosed endometriosis in a cohort of Chinese women.DesignRetrospective case–control study.SettingTertiary hospital.Patients709 women with endometriosis and 807 age matched controls between January 2018 and August 2019.InterventionAge at diagnosis, parity, gravida, BMI and self-reported dysmenorrhoea status were collected and the association of BMI and endometriosis was analysed.Measurement and main resultsOverall, the median BMI was not different between patients and controls (21.1 kg/m2 vs 20.9 kg/m2, p=0.223). According to the BMI categories for Asians/Chinese by WHO (underweight: <18.5 kg/m2, normal weight: 18.5–22.99 kg/m2, overweight: 23–27.49 kg/m2, obese: ≥27.50 kg/m2), overall, there was no difference in the association of BMI and endometriosis (p=0.112). 60% of patients were of normal weight. However, the OR of obese patients (BMI over 27.50 kg/m2) having endometriosis was1.979 (95% CI 1.15 to 3.52, p=0.0185), compared with women with normal weight. 50.3% patients reported dysmenorrhoea, and the OR of developing severe dysmenorrhoea in obese patients (BMI over 27.50 kg/m2) was 3.64 (95% CI 1.195 to 10.15, p=0.025), compared with patients with normal weight.ConclusionOur data demonstrate that overall there was no association between BMI and the incidence of endometriosis, but there was a significant increase in the incidence of endometriosis in obese women, compared with women with normal weight. Obesity was also a risk factor for severe dysmenorrhoea.

A potential role of hypophosphatemia for diagnosing convulsive seizures: A case‐control study

Epilepsia ◽  
2019 ◽  
Vol 60 (8) ◽  
pp. 1580-1585 ◽  
Author(s):  
Pierre Barras ◽  
Francesca Siclari ◽  
Olivier Hügli ◽  
Andrea O. Rossetti ◽  
Olivier Lamy ◽  
...  
Keyword(s):  
Potential Role ◽  
Case Control Study ◽  
Case Control ◽  
Convulsive Seizures ◽  
Control Study

Potential role of post-transplant hypogammaglobulinemia in the risk of Clostridium difficile infection after kidney transplantation: a case–control study

Infection ◽  
2015 ◽  
Vol 43 (4) ◽  
pp. 413-422 ◽  
Author(s):  
Julia Origüen ◽  
Mario Fernández-Ruiz ◽  
Carlos Lumbreras ◽  
María Ángeles Orellana ◽  
Francisco López-Medrano ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Clostridium Difficile ◽  
Clostridium Difficile Infection ◽  
Potential Role ◽  
Case Control Study ◽  
Case Control ◽  
Post Transplant ◽  
Control Study

Familial multiple sclerosis: does consanguinity have a role?

2010 ◽  
Vol 17 (4) ◽  
pp. 487-489 ◽  
Author(s):  
M Al Jumah ◽  
S Kojan ◽  
A Al Khathaami ◽  
I Al Abdulkaream ◽  
M Al Blawi ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Potential Role ◽  
Case Control Study ◽  
Case Control ◽  
Parental Consanguinity ◽  
Affected Relative ◽  
History Of ◽  
Estimate Prevalence ◽  
Control Study

Parental consanguinity (PC) may be a risk factor for familial multiple sclerosis (FMS) throughout inbred communities. The objective of this report was to estimate prevalence of FMS and rate of PC among FMS versus non-FMS patients. All Saudi MS patients were identified from our registry. The history of PC was analyzed as a case-control study. In total 141 MS patients were identified. Of these, 30 (21%) reported having at least one affected relative, 37.6% reported PC and 16% presented first-degree PC. In addition, FMS patients were more likely than non-FMS patients to report PC. In conclusion, FMS is prevalent among Saudi MS patients. MS patients with a history of PC were more likely to have FMS, suggesting a potential role of consanguinity.

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