The use of preoperative prognostic nutritional index and age to predict postoperative delirium in elderly patients

2020 ◽  
Vol 20 (5) ◽  
pp. 805-806
Author(s):  
Shao‐Hua Liu ◽  
Fu‐Shan Xue ◽  
Hai‐Jun Hou
Keyword(s):  
Elderly Patients ◽  
Postoperative Delirium ◽  
Prognostic Nutritional Index ◽  
Nutritional Index

Preoperative prognostic nutritional index predicts postoperative delirium in elderly patients after hip fracture surgery

2020 ◽  
Vol 20 (4) ◽  
pp. 487-494 ◽  
Author(s):  
Hailin Xing ◽  
Dong Xiang ◽  
Yunxiang Li ◽  
Xiaoli Ji ◽  
Guozhu Xie
Keyword(s):  
Hip Fracture ◽  
Elderly Patients ◽  
Postoperative Delirium ◽  
Prognostic Nutritional Index ◽  
Hip Fracture Surgery ◽  
Nutritional Index ◽  
Fracture Surgery

scholarly journals Prognostic nutritional index in elderly patients hospitalized for acute heart failure

2020 ◽  
Vol 7 (5) ◽  
pp. 2479-2484 ◽  
Author(s):  
Matteo Candeloro ◽  
Marcello Di Nisio ◽  
Martina Balducci ◽  
Stefano Genova ◽  
Emanuele Valeriani ◽  
...  
Keyword(s):  
Heart Failure ◽  
Elderly Patients ◽  
Acute Heart Failure ◽  
Prognostic Nutritional Index ◽  
Nutritional Index

scholarly journals Clinical and therapeutic features and prognostic factors of metastatic colorectal cancer over age 80: a retrospective study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hiroyuki Hisada ◽  
Yu Takahashi ◽  
Manabu Kubota ◽  
Haruhisa Shimura ◽  
Ei Itobayashi ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Prognostic Factors ◽  
Elderly Patients ◽  
Metastatic Colorectal Cancer ◽  
Carcinoembryonic Antigen ◽  
Prognostic Nutritional Index ◽  
Hazard Ratio ◽  
Elderly Group ◽  
Younger Patients ◽  
Nutritional Index

Abstract Background Colorectal cancer (CRC) is one of the most common cancers in the world. The number of elderly patients with CRC increases due to aging of the population. There are few studies that examined chemotherapy and prognostic factors in metastatic colorectal cancer (mCRC) patients aged ≥ 80 years. We assessed the efficacy of chemotherapy and prognostic factors among patients with mCRC aged ≥ 80 years. Methods We retrospectively analyzed clinical and laboratory findings of 987 patients newly diagnosed with CRC at Asahi General Hospital (Chiba, Japan) between January 2012 and December 2016. The Kaplan–Meier method was used for the overall survival (OS) and the log-rank test was used to identify difference between patients. A multivariate Cox proportional hazard regression analysis was performed to determine the hazard ratios and 95% confidence intervals (CIs) of prognostic factors among super-elderly patients. Results In total, 260 patients were diagnosed with mCRC (super-elderly group: n = 43, aged ≥ 80 years and younger group, n = 217, aged < 80 years). The performance status and nutritional status were worse in the super-elderly group than in the younger group. The OS of super-elderly patients who received chemotherapy was worse than that of younger patients (18.5 vs. 28.8 months; P = 0.052), although the difference was not significant. The OS of patients who received chemotherapy tended to be longer than that of those who did not; however, there were no significant differences in OS in the super-elderly group (18.5 vs. 8.4 months P = 0.33). Multivariate analysis revealed that carcinoembryonic antigen levels ≥ 5 ng/mL (hazard ratio: 2.27; 95% CI 1.09–4.74; P = 0.03) and prognostic nutritional index ≤ 35 (hazard ratio: 8.57; 95% CI 2.63–27.9; P = 0.0003) were independently associated with poor OS in the super-elderly group. Conclusions Patients with mCRC aged ≥ 80 years had lower OS than younger patients even though they received chemotherapy. Carcinoembryonic antigen and prognostic nutritional index were independent prognostic factors in super-elderly patients with mCRC, but chemotherapy was not. Trial registration: retrospectively registered.

Prognostic nutritional index (PNI): A predictive factor for elderly patients with COPD

2020 ◽  
Author(s):  
Eiko Suzuki ◽  
Naoko Kawata ◽  
Jun Ikari ◽  
Rie Anazawa ◽  
Masaki Suzuki ◽  
...  
Keyword(s):  
Elderly Patients ◽  
Predictive Factor ◽  
Prognostic Nutritional Index ◽  
Nutritional Index

scholarly journals Preoperative prognostic nutritional index is useful factor for predicting postoperative delirium after primary total joint arthroplasty

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Jie Chen ◽  
Chaojun Zheng ◽  
Jinxiu Zhong ◽  
Guanglei Zhao ◽  
Jingsheng Shi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Total Joint Arthroplasty ◽  
Postoperative Delirium ◽  
Univariate Analysis ◽  
Multivariate Logistic Regression Analysis ◽  
Prognostic Nutritional Index ◽  
Joint Arthroplasty ◽  
Time Duration ◽  
Simple Method ◽  
Nutritional Index

Abstract Background Postoperative delirium (PD), as an acute brain failure, is widely reported as a very common postoperative complication, and it is closely associated with increased morbidity and mortality. Recently, malnutrition is reported as one of the risk factors for PD. The prognostic nutritional index (PNI) is a simple method for nutritional evaluation. However, few studies have discussed the effectiveness of PNI as a nutritional assessment in predicting PD after primary total joint arthroplasty (TJA). The aim of this study is to investigate potential risk factors including PNI for PD following primary TJA. Methods A retrospective analysis of 994 patients was performed to identify risk factors associated with PD after primary TJA by using univariate and multivariate analyses. A receiver operating characteristic curve and the area under the curve were applied to evaluate the significant results of the multivariate analysis and the optimal cutoff value (CV). Results Postoperatively, sixty-seven patients (67/994, 6.7 %) experienced PD. Univariate analysis demonstrated that operative time, duration of anesthesia, age, hypertension, serum albumin, and PNI differed between the PD and non-PD groups (P < 0.05). Multivariate logistic regression analysis showed that the preoperative PNI (odds ratio [OR]: 0.908; 95 % confidence interval [CI]: 0.840–0.983; CV: 47.05), age of patients (OR: 1.055; 95 % CI: 1.024–1.087; CV: 73.5 years), and hypertension (OR: 1.798; 95 % CI: 1.047–3.086), were independently associated with PD (P < 0.05). Conclusions A low preoperative PNI associated with malnutrition was demonstrated to be an independent risk factor for PD following primary TJA. Patients with preoperative low PNI should be cautioned and provided with adequate nutritional intervention to reduce postoperative PD.

Prognostic nutritional index is a predictor of mortality in elderly patients with chronic kidney disease

2021 ◽  
Author(s):  
Dilek Barutcu Atas ◽  
Murat Tugcu ◽  
Ebru Asicioglu ◽  
Arzu Velioglu ◽  
Hakki Arikan ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Elderly Patients ◽  
Prognostic Nutritional Index ◽  
Nutritional Index

Low Preoperative Prognostic Nutritional Index Predicts Poor Survival Post-gastrectomy in Elderly Patients with Gastric Cancer

2016 ◽  
Vol 23 (11) ◽  
pp. 3669-3676 ◽  
Author(s):  
Katsunobu Sakurai ◽  
Tatsuro Tamura ◽  
Takahiro Toyokawa ◽  
Ryosuke Amano ◽  
Naoshi Kubo ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Elderly Patients ◽  
Prognostic Nutritional Index ◽  
Poor Survival ◽  
Nutritional Index

scholarly journals Clinical and Therapeutic Features and Prognostic Factors of Metastatic Colorectal Cancer Over Age 80: A Retrospective Study

2020 ◽  
Author(s):  
Hiroyuki Hisada ◽  
Yu Takahashi ◽  
Manabu Kubota ◽  
Haruhisa Shimura ◽  
Ei Itobayashi ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Prognostic Factors ◽  
Elderly Patients ◽  
Metastatic Colorectal Cancer ◽  
Carcinoembryonic Antigen ◽  
Prognostic Nutritional Index ◽  
Hazard Ratio ◽  
Elderly Group ◽  
Younger Patients ◽  
Nutritional Index

Abstract Background Colorectal cancer (CRC) is one of the most common cancers in the world. The number of elderly patients with CRC increases due to aging of the population. There are few studies that examined chemotherapy and prognostic factors in metastatic colorectal cancer (mCRC) patients aged ≥80 years. We assessed the efficacy of chemotherapy and prognostic factors among patients with mCRC aged ≥80 years.Methods We retrospectively analyzed clinical and laboratory findings of 987 patients newly diagnosed with CRC at Asahi General Hospital (Chiba, Japan) between January 2012 and December 2016. Kaplan-Meir method was used for the overall survival (OS) and the log-rank test was used to identify difference between patients. A multivariate Cox proportional hazard regression analysis was performed to determine the hazard ratios and 95% confidence intervals (CIs) of prognostic factors among super-elderly patients.Results In total, 260 patients were diagnosed with mCRC (super-elderly group: n = 43, aged ≥80 years and younger group, n = 217, aged <80 years). The performance status and nutritional status were worse in the super-elderly group than in the younger group. The OS of super-elderly patients who received chemotherapy was worse than that of younger patients (18.5 vs. 28.8 months; P = 0.057), although the difference was not significant. The OS of patients who received chemotherapy tended to be longer than that of those who did not; however, there were no significant differences in OS in the super-elderly group (18.5 vs. 8.4 months P = 0.33). Multivariate analysis revealed that carcinoembryonic antigen levels ≥5 ng/mL (hazard ratio: 2.27; 95% CI: 1.09–4.74; P = 0.03) and prognostic nutritional index ≤35 (hazard ratio: 8.57; 95% CI: 2.63–27.9; P = 0.0003) were independently associated with poor OS in the super-elderly group.Conclusions Patients with mCRC aged ≥80 years had lower OS than younger patients even though they received chemotherapy. Carcinoembryonic antigen and prognostic nutritional index were independent prognostic factors in super-elderly patients with mCRC, but chemotherapy was not.Trial registration retrospectively registered.

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