Objectives. To examine if major depressive episodes can predict risk chances for suicidal ideation, suicide plans, and suicide attempts among African American males while adjusting for covariates of age, education, and income. Methods. Data from the 2018 National Survey on Drug Use and Health were extracted and analyzed. We found data for 2,301 adult African American men with and without major depressive episodes, representing a population size of 13,210,069.53 in the United States. Results. African American men with major depressive episodes were at higher risk for suicidal ideation and suicide planning than their counterparts without a major depressive episode. However, the two groups with and without major depressive episodes had equal risk chances for suicide attempts. Conclusions. A closer examination of suicide covariate variables among African American men with and without a major depressive episode furnishes critical distinctions between the two populations. This can facilitate more responsive, tailored suicide prevention strategies for the male African American population, especially among the at-risk male adults in this group with major depressive episodes.