Covariate Health Determinants of Suicidal Ideation, Suicide Plans, and Suicide Attempts among African American Males with and without Major Depressive Episodes

2021 ◽  
Author(s):  
Areen Omary
Keyword(s):  
African American ◽  
Suicidal Ideation ◽  
African American Males ◽  
Depressive Episode ◽  
Major Depressive Episode ◽  
Suicide Attempts ◽  
African American Men ◽  
Major Depressive ◽  
Major Depressive Episodes ◽  
Depressive Episodes

Objectives. To examine if major depressive episodes can predict risk chances for suicidal ideation, suicide plans, and suicide attempts among African American males while adjusting for covariates of age, education, and income. Methods. Data from the 2018 National Survey on Drug Use and Health were extracted and analyzed. We found data for 2,301 adult African American men with and without major depressive episodes, representing a population size of 13,210,069.53 in the United States. Results. African American men with major depressive episodes were at higher risk for suicidal ideation and suicide planning than their counterparts without a major depressive episode. However, the two groups with and without major depressive episodes had equal risk chances for suicide attempts. Conclusions. A closer examination of suicide covariate variables among African American men with and without a major depressive episode furnishes critical distinctions between the two populations. This can facilitate more responsive, tailored suicide prevention strategies for the male African American population, especially among the at-risk male adults in this group with major depressive episodes.

Work stress as a risk factor for major depressive episode(s)

2004 ◽  
Vol 35 (6) ◽  
pp. 865-871 ◽  
Author(s):  
JIANLI WANG
Keyword(s):  
Multivariate Analysis ◽  
Risk Factor ◽  
Major Depression ◽  
Work Stress ◽  
Depressive Episode ◽  
Major Depressive Episode ◽  
Working Population ◽  
Major Depressive ◽  
Major Depressive Episodes ◽  
Depressive Episodes

Background. Major depression is a prevalent mental disorder in the general population, with a multi-factorial etiology. However, work stress as a risk factor for major depression has not been well studied.Method. Using a longitudinal study design, this analysis investigated the association between the levels of work stress and major depressive episode(s) in the Canadian working population, aged 18 to 64 years. Data from the longitudinal cohort of the Canadian National Population Health Survey (NPHS) were used (n=6663). The NPHS participants who did not have major depressive episodes (MDE) at baseline (1994–1995 NPHS) were classified into four groups by the quartile values of the baseline work stress scores. The proportion of MDE of each group was calculated using the 1996–1997 NPHS data.Results. The first three quartile groups had a similar risk of MDE. Those who had a work stress score above the 75th percentile had an elevated risk of MDE (7·1%). Using the 75th percentile as a cut-off, work stress was significantly associated with the risk of MDE in multivariate analysis (odds ratio=2·35, 95% confidence interval 1·54–3·77). Other factors associated with MDE in multivariate analysis included educational level, number of chronic medical illnesses and child and adulthood traumatic events. There was no evidence of effect modification between work stress and selected sociodemographic, clinical and psychosocial variables.Conclusions. Work stress is an independent risk factor for the development of MDE in the working population. Strategies to improve working environment are needed to keep workers mentally healthy and productive.

scholarly journals Major depressive episode among university students in Southern Brazil

2020 ◽  
Vol 54 ◽  
pp. 11 ◽  
Author(s):  
Betina Daniele Flesch ◽  
Gbènankpon Mathias Houvèssou ◽  
Tiago Neuenfeld Munhoz ◽  
Anaclaudia Gastal Fassa
Keyword(s):  
University Students ◽  
Depressive Episode ◽  
Major Depressive Episode ◽  
Negative Impact ◽  
Multivariable Analysis ◽  
Prevalence Ratio ◽  
Southern Brazil ◽  
Major Depressive ◽  
Major Depressive Episodes ◽  
Depressive Episodes

INTRODUCTION: Depression is the leading cause of disability around the world, and it has been increasingly affecting young people. This study evaluates the prevalence and factors associated with major depression in university students, with emphasis on the influence of the academic field, chosen study area and the environment they are inserted. METHODS: A census of students who entered the university in the first semester of 2017 was held at a university in Southern Brazil. The outcome of major depressive episode was evaluated using the Patient Health Questionnaire-9, considered when the individual had five or more depressive symptoms for at least one week. Its prevalence was estimated, and the associated factors were examined by the hierarchical multivariable analysis using the Poisson regression model. RESULTS: A total of 32% (95% confidence interval 29.9–34.2) of university students presented a major depressive episode, and the problem was more frequent among women (prevalence ratio [PR] = 1.59); people aged 21 to 23 years (PR = 1.24); those with a family history of depression (PR = 1.27); minorities’ sexual orientation (homosexuals, PR = 1.64, and bisexuals, PR = 1.69); who lived with friends or colleagues (PR = 1.36); students in the area of applied social and human sciences (PR = 1.28), and linguistics, language and literature, and art (PR = 1.25). The worst academic performance (PR = 2.61), alcohol abuse (PR = 1.25), and illicit drug use (PR = 1.30) were also positively associated with major depressive episode. CONCLUSION: In addition to individual, family, and behavioral aspects, already described as risk factors for major depressive episodes in the general population, academic aspects also influence the occurrence of depression among university students. Considering the high prevalence of major depressive episode and its negative impact on health, public and institutional policies are necessary to focus on students’ mental health promotion and care.

scholarly journals Underdiagnosis of Major Depressive Episodes in Hemodialysis Patients: The Need for Screening and Patient Education

2021 ◽  
Vol 10 (18) ◽  
pp. 4109
Author(s):  
Wojciech Orzechowski ◽  
Wiktor Buczek ◽  
Joanna Emma Szczerba ◽  
Ryszard Gellert ◽  
Andrzej Rydzewski ◽  
...  
Keyword(s):  
Depressive Episode ◽  
Major Depressive Episode ◽  
Coping Styles ◽  
Well Being ◽  
Major Depressive ◽  
Dialysis Vintage ◽  
Metacognitive Beliefs ◽  
Perception Of Self ◽  
Major Depressive Episodes ◽  
Depressive Episodes

This article aims to identify the reasons why patients with major depressive episode (MDE) do not seek treatment for their mental disorder. 89 out of 208 persons screened were diagnosed with major depressive episode using the Mini-International Neuropsychiatric Interview. 85 individuals with untreated depression filled out the following questionnaires: Beck Depression Inventory, List of Explanations of Well-Being (LEWB), Brief Measure to Assess Perception of Self-Influence on the Course of the Disease, Coping Inventory for Stressful Situations, Brief Method of Evaluating Coping with Disease, and Metacognitions Questionnaire. There were 43 women (50.6%) and 42 men (49.4%), aged 24 to 93 years (Mean (M) = 68.26 years; Standard Deviation (SD) = 14.19 years), with dialysis vintage ranging from 1 month to 33 years (M = 70.63 months; SD = 75.26 months). Among study patients, 70.6% declared that depression was the cause of their poor well-being, 75.3% attributed their depressive symptoms to kidney failure, and 49.4%, more specifically, to hemodialysis. A total of 64.7% of patients had a low perception of self-influence on the course of their kidney disease, and 58.5% presented a coping style focused on emotions. The most frequent dysfunctional metacognitive beliefs were negative beliefs about not controlling one’s own thoughts. This attitude was related to the low perception of self-influence on the course of the disease, maladaptive coping styles, and dysfunctional metacognitive beliefs.

scholarly journals Association between Depression and Renal Hyperfiltration in a General Chinese Population

2019 ◽  
Vol 44 (6) ◽  
pp. 1441-1452
Author(s):  
Miao Lin ◽  
Huibin Huang ◽  
Jin Yao ◽  
Jixing Liang ◽  
Liantao Li ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Depressive Episode ◽  
Major Depressive Episode ◽  
Structured Interview ◽  
Multivariable Logistic Regression Analysis ◽  
Major Depressive ◽  
Renal Hyperfiltration ◽  
A Minor ◽  
Major Depressive Episodes ◽  
Depressive Episodes

Background: Depression is prevalent in patients with all stages of CKD and is associated with adverse outcome. Abnormally elevated GFR, or hyperfiltration, may play a crucial role in the initiation and progression of CKD. However, the association between depression and hyperfiltration is not known. The aim of this study is to investigate the relationship between depression and hyperfiltration. Methods: This was an observational cross-sectional study. A total of 3,716 volunteers (1,303 males and 2,413 females) aged 40–75 years without CKD from a community in China were included for the study. Depressive symptoms and the presence of a minor or major depressive episode were assessed with the 9-item Patient Health Questionnaire (PHQ-9) and Diagnostic and Statistical Manual of Mental Disorders (4th edition)-based structured interview, respectively. Results: The mean age of the participants in the present study was 53.8 ± 9.0 years. 115 participants had clinically relevant depression, and 122 participants had a minor or major depressive episode. In a multivariable logistic regression analysis adjusted for potential confounders, the association between clinically relevant depression and renal hyperfiltration remained significant in men but not in women. As compared with men without depression (PHQ <5) or depressive episodes, those with clinically relevant depression (PHQ ≥10) had a significantly higher risk of renal hyperfiltration. The fully adjusted OR (95% CI) was 4.81 (1.62–14.30, p = 0.005), those with a major depressive episode had a higher risk of renal hyperfiltration (OR 7.45; 95% CI 2.04–27.21, p = 0.002). Conclusion: Depressive symptoms and major depressive episodes are associated with renal hyperfiltration in middle-aged and elderly Chinese men without CKD. Future studies are needed to verify and clarify the role of depression in the development of abnormally high eGFR and CKD.

scholarly journals Blood microbiota and metabolomic signature of major depression before and after antidepressant treatment: a prospective case–control study

2021 ◽  
Vol 46 (3) ◽  
pp. E358-E368
Author(s):  
Dragos Ciocan ◽  
Anne-Marie Cassard ◽  
Laurent Becquemont ◽  
Céline Verstuyft ◽  
Cosmin Sebastian Voican ◽  
...  
Keyword(s):  
Depressive Episode ◽  
Major Depressive Episode ◽  
Antidepressant Treatment ◽  
Case Control ◽  
Healthy Controls ◽  
Major Depressive ◽  
Rdna Sequencing ◽  
Before And After ◽  
Major Depressive Episodes ◽  
Depressive Episodes

Background: The microbiota interacts with the brain through the gut–brain axis, and a distinct dysbiosis may lead to major depressive episodes. Bacteria can pass through the gut barrier and be found in the blood. Using a multiomic approach, we investigated whether a distinct blood microbiome and metabolome was associated with major depressive episodes, and how it was modulated by treatment. Methods: In this case–control multiomic study, we analyzed the blood microbiome composition, inferred bacterial functions and metabolomic profile of 56 patients experiencing a current major depressive episode and 56 matched healthy controls, before and after treatment, using 16S rDNA sequencing and liquid chromatography coupled to tandem mass spectrometry. Results: The baseline blood microbiome in patients with a major depressive episode was distinct from that of healthy controls (patients with a major depressive episode had a higher proportion of Janthinobacterium and lower levels of Neisseria) and changed after antidepressant treatment. Predicted microbiome functions confirmed by metabolomic profiling showed that patients who were experiencing a major depressive episode had alterations in the cyanoamino acid pathway at baseline. High baseline levels of Firmicutes and low proportions of Bosea and Tetrasphaera were associated with response to antidepressant treatment. Based on inferred baseline metagenomic profiles, bacterial pathways that were significantly associated with treatment response were related to xenobiotics, amino acids, and lipid and carbohydrate metabolism, including tryptophan and drug metabolism. Metabolomic analyses showed that plasma tryptophan levels are independently associated with response to antidepressant treatment. Limitations: Our study has some limitations, including a lack of information on blood microbiome origin and the lack of a validation cohort to confirm our results. Conclusion: Patients with depression have a distinct blood microbiome and metabolomic signature that changes after treatment. Dysbiosis could be a new therapeutic target and prognostic tool for the treatment of patients who are experiencing a major depressive episode.

scholarly journals El impacto del reforzamiento ambiental reducido en la predicción de la severidad de la depresión en cuidadores

2019 ◽  
Vol 35 (3) ◽  
pp. 357-363
Author(s):  
Fernando Lino Vázquez González ◽  
Lara López ◽  
Vanessa Blanco ◽  
Patricia Otero ◽  
Ángela J. Torres ◽  
...  
Keyword(s):  
Depressive Episode ◽  
Protective Factor ◽  
Major Depressive Episode ◽  
Depressive Symptomatology ◽  
Lower Probability ◽  
Major Depressive ◽  
High Prevalence ◽  
Major Depressive Episodes ◽  
Depressive Episodes ◽  
Subclinical Depression

Pese a sus dificultades para realizar actividades agradables y la alta prevalencia de depresión, no se ha analizado el refuerzo como predictor de la depresión en la población de cuidadores. El objetivo de este estudio fue analizar el refuerzo como predictor del nivel de depresión (sin depresión, depresión subclínica, episodio depresivo mayor) en cuidadores. Evaluadores independientes evaluaron las variables sociodemográficas del cuidador, la persona cuidada y la situación de cuidado, el refuerzo y la sintomatología depresiva mediante autoinformes, y clínicos expertos evaluaron el episodio depresivo mayor mediante la SCID-5-CV, en 592 cuidadores (87.2% mujeres; edad media = 55.4 años). La puntuación media en refuerzo fue 28.1. El refuerzo fue menor en cuidadores ≤55 años y de clase social baja-media/baja. Y mayor en cuidadores sin depresión que en aquellos con depresión subclínica y episodio depresivo mayor, y en cuidadores con depresión subclínica frente a aquellos con episodio depresivo mayor. Los cuidadores con mayor refuerzo tenían menor probabilidad de depresión subclínica (adjusted OR = 0.78, 95% CI 0.75-0.83) y episodio depresivo mayor (adjusted OR = 0.67, 95% CI 0.62-0.72). El refuerzo fue un factor de protección frente a la depresión subclínica y el episodio depresivo mayor en cuidadores. Reward has not been examined as a predictor of depression in the caregiver population despite the high prevalence of depression. The aim of this study was to analyze reward as a predictor of the level of depression (without depression, subclinical depression, major depressive episode) in caregivers. Independent evaluators evaluated the socio-demographic variables of the caregiver, the person receiving care, the situation of care, reward and depressive symptomatology through self-reports. Expert clinicians evaluated the prevalence of major depressive episodes using the SCID-5-CV in 592 caregivers (87.2% women, average age = 55.4 years). The average reward score was 28.1. Reward was lower in caregivers younger than 55 years old who belonged to a low/low-middle social class. Reward was higher in caregivers without depression than in those with subclinical depression and a major depressive episode. Reward was also higher in caregivers with subclinical depression versus those with a major depressive episode. Caregivers with higher reward had a lower probability of subclinical depression (adjusted OR = 0.78, 95% CI 0.75-0.83) and a major depressive episode (adjusted OR = 0.67, 95% CI 0.62-0.72). Reward was a protective factor against subclinical depression and a major depressive episode in caregivers.

Point prevalence of major depression in Estonia. Results from the 2006 Estonian Health Survey

2010 ◽  
Vol 25 (8) ◽  
pp. 485-490 ◽  
Author(s):  
A. Kleinberg ◽  
A. Aluoja ◽  
V. Vasar
Keyword(s):  
Health Status ◽  
Major Depression ◽  
Health Survey ◽  
Depressive Episode ◽  
Major Depressive Episode ◽  
Point Prevalence ◽  
Major Depressive ◽  
Major Depressive Episodes ◽  
Depressive Episodes ◽  
Estonian Population

AbstractAimThe study focuses on the point prevalence of major depressive episode in the Estonian population in 2006 and assesses the relationship of sociodemographic factors, health status indicators, alcohol use, and previous depressive episodes to major depression.MethodsThe present major depressive episode was assessed within the nationally representative, cross-sectional 2006 Estonian Health Survey (EHIS 2006), in which non-institutionalized individuals aged 18–84 years (n = 6105) were interviewed using the Mini-International Neuropsychiatric Interview (MINI).ResultsThe point prevalence of major depressive episode in the Estonian population was 5.6%. Depression was higher among females, in the non-Estonian ethnic group, among people older than 40 years, and in the lower-income group.ConclusionsThe point prevalence of major depressive episodes was comparable with the results of other population surveys, being a little higher than the average. Age, income, ethnicity, health status, self-rated health, and previous depressive episode were independent associates of depression.

A pharmacopsychometric overview of major depressive episodes in positive psychiatry

2018 ◽  
Vol 30 (6) ◽  
pp. 833-841 ◽  
Author(s):  
P. Bech
Keyword(s):  
Dose Response ◽  
Depressive Episode ◽  
Major Depressive Episode ◽  
Psychological Treatment ◽  
Well Being ◽  
Major Depressive ◽  
Patient Reported ◽  
Antidepressive Medication ◽  
Major Depressive Episodes ◽  
Depressive Episodes

ABSTRACTBackground:The use of the pharmacopsychometric triangle to enhance patient-reported well-being as the ultimate goal of treatment has most intensively been studied in patients with a major depressive episode.Methods:The review is structured on the pharmacopsychometric triangle in which the desired clinical effect of an antidepressive medication is balanced against the undesired side effects induced by this medication in terms of restored well-being. As a biological treatment, the antidepressive medication is compared clinically with both electroconvulsive therapy and psychological treatment.Results:In the process of this review, evidence from a dose–response study in patients suffering from a major depressive episode with an adequate duration and symptom severity has demonstrated that the dose–response relationship emerged when using the patient-reported well-being outcome rather than the symptomatic reduction as outcome.Conclusion:The pharmacopsychometric triangle is in patients with major depressive episodes providing important information within positive psychiatry.

Sign in / Sign up

Export Citation Format

Share Document