All the lumps are primarily not from breast—report of a metastatic breast lump in a cervical cancer survivor

2020 ◽  
Vol 26 (8) ◽  
pp. 1622-1624
Author(s):  
Suchana Kushvaha ◽  
Sangita Mehta ◽  
Firoz Rajan ◽  
Subramaniam R ◽  
Rupa Renganathan
Keyword(s):  
Cervical Cancer ◽  
Cancer Survivor ◽  
Metastatic Breast ◽  
Breast Lump ◽  
Cervical Cancer Survivor

Effect of a cervical cancer survivor story on willingness and behavioral change for Human Papillomavirus Vaccination: Randomized Controlled Trial (Preprint)

2021 ◽  
Author(s):  
Yukio Suzuki ◽  
Akiko Sukegawa ◽  
Yutaka Ueda ◽  
Masayuki Sekine ◽  
Takayuki Enomoto ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Randomized Controlled Trial ◽  
Human Papillomavirus ◽  
Cancer Survivor ◽  
Controlled Trial ◽  
Hpv Vaccination ◽  
Intervention Group ◽  
Control Group ◽  
Randomized Controlled ◽  
Cervical Cancer Survivor

BACKGROUND Providing adequate information to parents who have children eligible for human papillomavirus (HPV) vaccination is essential to overcoming vaccine hesitancy in Japan, where the government recommendation has been suspended. However, prior trials assessing the effect of brief educational tools showed only limited effects on increasing the willingness of parents to vaccinate their daughters. OBJECTIVE The aim of this trial was to assess the effect of a cervical cancer survivor story on the willingness of parents to get HPV vaccination for their daughters. METHODS In this double-blinded, randomized controlled trial implemented online, we enrolled 2175 participants aged 30–59 years in March 2020 via a webpage and provided them with a questionnaire related to the following aspects: awareness regarding HPV infection and HPV vaccination, and willingness for HPV vaccination. Participants were randomly assigned (1:1) to see a short film of cervical cancer survivor story or nothing, stratified by sex (male vs. female) and willingness to HPV vaccination prior to randomization (Yes vs. No). The primary endpoint was the rate of parents who agreed to HPV vaccination for their daughters. The secondary endpoint was the rate of parents who agreed to HPV vaccination for their daughters and the HPV vaccination rate at 3 months. RESULTS Among 2175 participants, 1266 (58.2%) were men and 909 (41.8%) were women. A total of 191 (8.8%) participants were willing to consider HPV vaccination prior to randomization. Only 339 (15.6%) participants were aware of the benefits of HPV vaccination. In contrast, 562 (25.8%) patients were aware of the adverse events of HPV vaccination. Although only 476 (21.9%) of the respondents displayed a willingness to vaccinate their daughters for HPV, there were 7.5% more respondents in the intervention group with this willingness immediately after watching the short movie (odds ratio [OR] 1.55, 95% CI 1.27-1.91). In a sub-analysis, the willingness to vaccinate daughters for HPV was 10.9% higher in males in the intervention group (OR 1.75, 95% CI 1.36-2.25); however, such a difference was not observed among females (OR 1.25, 95% CI 0.86-1.81). Male participants were more likely to have willingness for HPV vaccination compared to female participants. In the follow-up survey at 3 months, 1807 (83.1%) participants responded. Of these, 149 (8.2%) responded that they had had their daughters receive vaccination during the 3 months, even though we could not see the effect of the intervention; 77 (7.9%) in the intervention group and 72 (8.7%) in the control group. CONCLUSIONS A cervical cancer survivor story increases immediate willingness to consider HPV vaccination, but the effect does not last for 3 months. Furthermore, this narrative approach to parents did not increase vaccination rates in children eligible for HPV vaccination. CLINICALTRIAL UMIN Clinical Trials Registry UMIN000039273; https://upload.umin.ac.jp/cgi-open-bin/ctr/ctr_view.cgi?recptno=R000043714.

Pelvic floor dysfunction in the cervical cancer survivor

2020 ◽  
Vol 159 ◽  
pp. 316-317
Author(s):  
A. Greenwood ◽  
T. Castellano ◽  
A.K. Crim ◽  
L.L. Holman
Keyword(s):  
Cervical Cancer ◽  
Pelvic Floor ◽  
Cancer Survivor ◽  
Pelvic Floor Dysfunction ◽  
Cervical Cancer Survivor

Finding myself as a cervical cancer survivor: A qualitative study

2019 ◽  
Vol 41 ◽  
pp. 143-148
Author(s):  
Elizabeth Ochoa ◽  
Gloria M. Carrillo ◽  
Daniel Sanabria
Keyword(s):  
Cervical Cancer ◽  
Qualitative Study ◽  
Cancer Survivor ◽  
Cervical Cancer Survivor

scholarly journals Pemaknaan Hidup Survivor Kanker Serviks selama Terapi Pengobatan: Literature Review

2021 ◽  
Vol 4 (1) ◽  
pp. 16-25
Author(s):  
Regina Aprilia Roberto ◽  
Wahyu Hidayati
Keyword(s):  
Cervical Cancer ◽  
Literature Review ◽  
Cancer Survivor ◽  
Meaning In Life ◽  
Treatment Process ◽  
Meaning Of Life ◽  
Life Meaning ◽  
Inclusion Criteria ◽  
Finding Meaning ◽  
Cervical Cancer Survivor

Introduction: Cervical cancer treatment process proves to make women experiencing emotional distress that brings new problems in life. Women with cervical cancer who undergo treatment suffer affecting all aspects of life that impact on the meaning of life. There is limited literature review regarding life meaning resources and technique used by women with cervical cancer who undergo treatment. The aim of this study is to find out description about the meaningfulness in life of cervical cancer survivor during treatment period based on sources and technique of finding meaning. Methods: This study used literature review method. The literature search engines used are SCOPUS, SINTA and Google Scholar. The inclusion criteria of article were articles in Indonesian or English, containing sources and techniques for finding meaning in abstract, respondents cervical cancer survivor and published from 2011 to 2020.  Results: Eleven articles show the existence of meaning in life build upon sources of meaning in life including creative, experimental, attitudinal, and hopeful values. Moreover, there are techniques in seeking meaning involving self-understanding, positive action, familiarity with relationships, deepening the values of the meaning of life and worship. Conclusion: The beginning of treatment process results feelings of meaningless, but efforts to make sense of life remain. Family support and spirituality were found to be the things that give the most meaning for cervical cancer survivors to survive.  

Circulating tumour cells and lung microvascular tumour cell retention in patients with metastatic breast and cervical cancer

2015 ◽  
Vol 356 (2) ◽  
pp. 872-879 ◽  
Author(s):  
Dieter J.E. Peeters ◽  
Anja Brouwer ◽  
Gert G. Van den Eynden ◽  
Annemie Rutten ◽  
Wendy Onstenk ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Tumour Cell ◽  
Metastatic Breast ◽  
Tumour Cells ◽  
Circulating Tumour Cells ◽  
Cell Retention ◽  
Breast And Cervical Cancer

scholarly journals Incidence and Patient Profile of Carcinoma Breast Patients Presenting in Surgical OPD in a Tertiary Care Hospital

2021 ◽  
Vol 15 (2) ◽  
pp. 65-68
Author(s):  
Sharmistha Roy ◽  
Mosammat Mira Pervin ◽  
Mohd Mejbahul Bahar ◽  
Samiron Kumar Mondal ◽  
Md Tariq Hasan
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Cancer Biology ◽  
Tertiary Care ◽  
Locally Advanced ◽  
Metastatic Breast ◽  
Care Hospital ◽  
Age Group ◽  
Breast Lump ◽  
Patient Profile

Breast cancer is one of the common cancers in women that causes financial health burden and or death in Bangladesh. Economically we are slowly rising from low to middle income country, which is changing our women's lifestyle. Risk factors of breast cancer include lifestyle factors like- age at first childbirth, parity, using oral contraceptives, BMI; which are also changing in our women. This study will look at our current incidence and patient profile of breast cancer patient. This is a retrospective study done in BIRDEM General Hospital. One hundred patient presenting with breast lump during the period of September 2018 -May 2019 were selected by purposive sampling. In <30 years age group 2 (13.6%) patient had cancer, 41% at <40 years, 53% in 51-60 , 83% in 61-70 age group. Thirty four out of 100 breast lump patient were diagnosed with cancer. Eleven had early cancer, 20 had locally advanced cancer, 3 presented with metastasis. In our study risk factor assessment did not show significant increase risk of in patients who are having cancer compared to those having benign breast disease with similar risk factors. The big number of advance and metastatic breast cancers in our study indicates self-breast examination and breast cancer screening program is still inadequate. Further research is required to find out breast cancer biology and pathogenesis rather than blindly accusing urbanized life style. Faridpur Med. Coll. J. 2020;15(2): 65-68

Phase I study of weekly treatment with paclitaxel injection concentrate for nanodispersion (PICN), a novel solvent and protein-free formulation of paclitaxel.

2013 ◽  
Vol 31 (15_suppl) ◽  
pp. 3039-3039
Author(s):  
Minish Mahendra Jain ◽  
Chetan Dilip Deshmukh ◽  
Shailesh Arjun Bondarde ◽  
Niraj Bhatt ◽  
Vijay Shinde ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Febrile Neutropenia ◽  
Phase I ◽  
Dose Range ◽  
Metastatic Breast ◽  
Fixed Dose ◽  
Weekly Schedule ◽  
Safety And Efficacy ◽  
Solid Malignancies ◽  
Grade 3

3039 Background: PICN is a novel solvent and protein-free 100-110 nm particle formulation of paclitaxel stabilized with polymer and lipid using Nanotecton Technology. Paclitaxel has shown superior safety and efficacy profile when administered on a weekly schedule. We studied safety, tolerability, and pharmacokinetics (PK) of PICN using a weekly schedule in patients with advanced solid malignancies. Methods: Patients aged18-65 years with advanced solid malignancies, ECOG performance status ≤ 2, estimated survival ≥ 12 weeks, and adequate organ function were enrolled. A standard phase I, 3+3 dose escalation design to determine the maximum tolerated dose (MTD) of PICN administered on a weekly schedule (three consecutive weeks, one week recovery) was employed. PICN dose was escalated at pre-determined fixed dose levels of 80, 100, 125, 150, 175, and 200 mg/m2. PICN was administered as a 30 min infusion without any premedication for hypersensitivity. Results: Twenty-one patients treated with PICN had a mean age of 52.1 yrs (range 35-67); 20 were female and entered with metastatic breast cancer (MBC; n=15), cervical cancer (n=3), skin cancer (n=2). One male had oral cancer. Doses studied were 80 (n=3), 100 (n=3), 125 (n=3), 150 (n=3), 175 (n=6), and 200 (n=3) mg/m2. Despite the lack of dexamethasone premedication, no patient receiving PICN reported hypersensitivity reaction. Two DLTs (neutropenia and febrile neutropenia; both grade 3) were reported at PICN 200 mg/m2. PICN PK (AUC0-24, AUC0-∞, and Cmax) increased in a dose proportionate manner from 80 to 200 mg/m2. Grade 3 or worse related AEs were: neutropenia, leucopenia, peripheral neuropathy, febrile neutropenia, anemia, thrombocytopenia, fatigue, syncope, hypotension and maculopapular rash. Partial responses were observed in MBC (100, 125, 150, 175, and 200 mg/m2) and cervical cancer (80 mg/m2). Conclusions: PICN on thrice monthly schedule was tolerable in the dose range evaluated. Two DTLs were reported: neutropenia and febrile neutropenia (both grade 3). Anti-tumor activity was observed in MBC and cervical cancer. Final trial data for PICN PK, safety, and efficacy will be presented at the conference. Clinical trial information: CTRI/2011/11/002124.

Metastatic breast lump: A rare presentation of squamous cell lung cancer

2012 ◽  
Vol 1 (2) ◽  
pp. 97 ◽  
Author(s):  
Kaushik Saha ◽  
Debraj Jash ◽  
SourindraN Banerjee ◽  
Amitabha Sengupta
Keyword(s):  
Lung Cancer ◽  
Squamous Cell ◽  
Cell Lung Cancer ◽  
Metastatic Breast ◽  
Squamous Cell Lung Cancer ◽  
Breast Lump ◽  
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