Mean Flow and Turbulent Stress Estimation Using DPIV in Pulsatile Flow Through Mechanical Heart Valve

2000 ◽  
Author(s):  
Amirthaganesh Subramanian ◽  
Haining Mu ◽  
Jaikrishnan R. Kadambi ◽  
Hiroaki Harasaki ◽  
Mark P. Wernet
Keyword(s):  
Heart Valve ◽  
Pulsatile Flow ◽  
Laser Doppler Anemometry ◽  
Measurement Techniques ◽  
Mechanical Heart Valve ◽  
Accurate Estimation ◽  
Turbulent Stress ◽  
Mean Flow ◽  
Flow Loop ◽  
Pulsatile Flows

Abstract Accurate estimation of turbulent stresses in pulsatile flows is very important in the design of mechanical heart valves to reduce thromboembolism and hemolysis. The flow within the lumen of a fully transparent bileaflet mechanical heart valve model, in the “mitral” position of an in-vitro pulsatile flow loop, is characterized using digital particle image velocimetry (DPIV). A phase-averaging technique is used to obtain the mean velocities and turbulent stresses. The results are compared with those obtained using laser Doppler anemometry which shows good agreement between the two measurement techniques, thereby validating the integrity of the DPIV measurements in the conditionally sampled time dependent flow. Convergence and accuracy issues involving turbulent stress measurements with DPIV in pulsatile flows are addressed in this paper.

Nonquasi-Steady Character of Pulsatile Flow in Human Coronary Arteries

1985 ◽  
Vol 107 (1) ◽  
pp. 24-28 ◽  
Author(s):  
F. F. Mark ◽  
C. B. Bargeron ◽  
O. J. Deters ◽  
M. H. Friedman
Keyword(s):  
Coronary Arteries ◽  
Pulsatile Flow ◽  
Laser Doppler Anemometry ◽  
Main Channel ◽  
Left Main ◽  
Vascular Cast ◽  
Pulsatile Flows ◽  
Flow Through ◽  
The Mean ◽  
Flow Experiments

This experiment was conducted to determine if the pulsatile flow through the proximal portion of the left coronary artery system in man exhibits quasi-steady characteristics. Steady and pulsatile flows were passed through an idealized model whose dimensions were based on a vascular cast. The mean Reynolds number was 180 and the unsteadiness number was 2.7. Velocity profiles were measured by laser Doppler anemometry at several locations along diameters in the parent and both daughter channels in the neighborhood of the “left main” bifurcation. Analysis of the results along one diameter in the “left main” channel shows that unsteady flow in the larger coronary arteries may not be simulated by a series of steady flow experiments.

Flashback in a Swirl Burner With Cylindrical Premixing Zone

2001 ◽  
Author(s):  
Jassin Fritz ◽  
Martin Kröner ◽  
Thomas Sattelmayer
Keyword(s):  
Flame Propagation ◽  
Gas Turbines ◽  
High Speed ◽  
Vortex Breakdown ◽  
Swirling Flow ◽  
Laser Doppler Anemometry ◽  
Burning Velocity ◽  
Turbulent Flame ◽  
Measurement Techniques ◽  
Mean Flow

Flame flashback from the combustion chamber into the mixing zone is one of the inherent problems of lean premixed combustion and essentially determines the reliability of low NOx burners. Generally, flashback can be initiated by one of the following four phenomena: flashback due to the conditions in the boundary layer, flashback due to turbulent flame propagation in the core flow, flashback induced by combustion instabilities and flashback caused by combustion induced vortex breakdown. In this study, flashback in a swirling tubular flow was investigated. In order to draw maximum benefit from the tests with respect to the application in gas turbines, the radial distribution of the axial and circumferential momentum in the tube was selected such that the typical character of a flow in mixing zones of premix burners without centerbody was obtained. A single burner test rig has been designed to provoke flashback with the preheating temperature, the equivalence ratio and the mean flow rate being the influencing parameters. The flame position within the mixing section is detected by a special optical flame sensor array, which allows the control of the experiment and furthermore the triggering of the measurement techniques. The burning velocity of the fuel has been varied by using natural gas or hydrogen. The characteristics of the flashback, the unsteady swirling flow during the flame propagation, the flame dynamics and the reaction zones have been investigated by applying High Speed Video recordings, the Laser Doppler Anemometry and the Laser Induced Fluorescence. The presented results show that a combustion induced vortex breakdown is the dominating mechansim of the observed flashback. This mechanism is very sensitive to the momentum distribution in the vortex core. By adding axial momentum around the mixing tube axis, the circumferential velocity gradient is reduced and flashback can be prevented.

Flashback in a Swirl Burner With Cylindrical Premixing Zone

2004 ◽  
Vol 126 (2) ◽  
pp. 276-283 ◽  
Author(s):  
J. Fritz ◽  
M. Kro¨ner ◽  
T. Sattelmayer
Keyword(s):  
Flame Propagation ◽  
Gas Turbines ◽  
High Speed ◽  
Vortex Breakdown ◽  
Swirling Flow ◽  
Laser Doppler Anemometry ◽  
Burning Velocity ◽  
Turbulent Flame ◽  
Measurement Techniques ◽  
Mean Flow

Flame flashback from the combustion chamber into the mixing zone is one of the inherent problems of lean premixed combustion and essentially determines the reliability of low NOx burners. Generally, flashback can be initiated by one of the following four phenomena: flashback due to the conditions in the boundary layer, flashback due to turbulent flame propagation in the core flow, flashback induced by combustion instabilities and flashback caused by combustion induced vortex breakdown. In this study, flashback in a swirling tubular flow was investigated. In order to draw maximum benefit from the tests with respect to the application in gas turbines, the radial distribution of the axial and circumferential momentum in the tube was selected such that the typical character of a flow in mixing zones of premix burners without centerbody was obtained. A single burner test rig has been designed to provoke flashback with the preheating temperature, the equivalence ratio and the mean flow rate being the influencing parameters. The flame position within the mixing section is detected by a special optical flame sensor array, which allows the control of the experiment and furthermore the triggering of the measurement techniques. The burning velocity of the fuel has been varied by using natural gas or hydrogen. The characteristics of the flashback, the unsteady swirling flow during the flame propagation, the flame dynamics and the reaction zones have been investigated by applying high-speed video recordings, the laser Doppler anemometry and the laser induced fluorescence. The presented results show that a combustion induced vortex breakdown is the dominating mechanism of the observed flashback. This mechanism is very sensitive to the momentum distribution in the vortex core. By adding axial momentum around the mixing tube axis, the circumferential velocity gradient is reduced and flashback can be prevented.

Direct numerical simulation of the pulsatile flow through an aortic bileaflet mechanical heart valve

2009 ◽  
Vol 622 ◽  
pp. 259-290 ◽  
Author(s):  
M. D. DE TULLIO ◽  
A. CRISTALLO ◽  
E. BALARAS ◽  
R. VERZICCO
Keyword(s):  
Numerical Simulation ◽  
Direct Numerical Simulation ◽  
Heart Valve ◽  
Pulsatile Flow ◽  
Damage Index ◽  
Mechanical Heart Valve ◽  
Immersed Boundary ◽  
Reynolds Stresses ◽  
Bileaflet Mechanical Heart Valve ◽  
Flow Through

This work focuses on the direct numerical simulation of the pulsatile flow through a bileaflet mechanical heart valve under physiological conditions and in a realistic aortic root geometry. The motion of the valve leaflets has been computed from the forces exerted by the fluid on the structure both being considered as a single dynamical system. To this purpose the immersed boundary method, combined with a fluid–structure interaction algorithm, has shown to be an inexpensive and accurate technique for such complex flows. Several complete flow cycles have been simulated in order to collect enough phase-averaged statistics, and the results are in good agreement with experimental data obtained for a similar configuration. The flow analysis, strongly relying on the data accessibility provided by the numerical simulation, shows how some features of the leaflets motion depend on the flow dynamics and that the criteria for the red cell damages caused by the valve need to be formulated using very detailed analysis. In particular, it is shown that the standard Eulerian computation of the Reynolds stresses, usually employed to assess the risk of haemolysis, might not be adequate on several counts: (i) Reynolds stresses are only one part of the solicitation, the other part being the viscous stresses, (ii) the characteristic scales of the two solicitations are very different and the Reynolds stresses act on lengths much larger than the red cells diameter and (iii) the Eulerian zonal assessment of the stresses completely misses the information of time exposure to the solicitation which is a fundamental ingredient for the phenomenon of haemolysis. Accordingly, the trajectories of several fluid particles have been tracked in a Lagrangian way and the pointwise instantaneous viscous stress tensor has been computed along the paths. The tensor has been then reduced to an equivalent scalar using the von Mises criterion, and the blood damage index has been evaluated following Grigioni et al. (Biomech. Model Mechanobiol., vol. 4, 2005, p. 249).

The Design of the Mechanical Heart Valve by Using the Parametric Method

2013 ◽  
Vol 683 ◽  
pp. 657-660
Author(s):  
Yong Zhang ◽  
Liang Liang Wu ◽  
Feng Zhou ◽  
Tian Xue You ◽  
Guo Jiang Wan ◽  
...  
Keyword(s):  
Finite Element Method ◽  
Finite Element ◽  
Heart Valve ◽  
Pulsatile Flow ◽  
Parametric Method ◽  
Mechanical Heart Valve ◽  
Hydrodynamic Performance ◽  
Flow Test ◽  
Central Flow ◽  
Element Method

In order to reveal the design regularity for the various sizes of mechanical heart valve(MHV), the theoretical and parametric finite element method (FEM) were adopted to investigate the influence of the MHV pivot distance on the valve performance in this paper. Result shows that the characteristics of central flow can be improved for all sizes of valve with the increasing of the pivot distance, and the acceptable hydrodynamic performance of the MHV designed in this method was also shown in the valve pulsatile flow test, which proved that the parametric method is a useful tool for MHV design.

A Comparison of a Moderate with Moderate-high Intensity Oral Anticoagulant Treatment in Patients with Mechanical Heart Valve Prostheses

1997 ◽  
Vol 77 (05) ◽  
pp. 0839-0844 ◽  
Author(s):  
Vittorio Pengo ◽  
Fabio Barbero ◽  
Alberto Banzato ◽  
Elisabetta Garelli ◽  
Franco Noventa ◽  
...  
Keyword(s):  
Heart Valve ◽  
High Intensity ◽  
Oral Anticoagulant ◽  
Oral Anticoagulants ◽  
Mechanical Heart Valve ◽  
Moderate Intensity ◽  
Minor Bleeding ◽  
Anticoagulant Treatment ◽  
Oral Anticoagulant Treatment ◽  
Valve Prostheses

SummaryBackground. The long-term administration of oral anticoagulants to patients with mechanical heart valve prostheses is generally accepted. However, the appropriate intensity of oral anticoagulant treatment in these patients is still controversial.Methods and Results. From March 1991 to March 1994, patients referred to the Padova Thrombosis Center who had undergone mechanical heart valve substitution at least 6 months earlier were randomly assigned to receive oral anticoagulants at moderate intensity (target INR = 3) or moderate-high intensity (target INR = 4). Principal end points were major bleeding, thromboembolism and vascular death. Minor bleeding was a secondary end-point.A total of 104 patients were assigned to the target 3 group and 101 to the target 4 group; they were followed for from 1.5 years to up 4.5 years (mean, 3 years). Principal end-points occurred in 13 patients in the target 3 group (4 per 100 patient-years) and in 20 patients in the target 4 group (6.9 per 100 patient-years). Major hemorrhagic events occurred in 15 patients, 4 in the target 3 group (1.2 per 100 patient-years) and 11 in the target 4 group (3.8 per 100 patient-years) (p = 0.019). The 12 recorded episodes of thromboembolism, 4 of which consisted of a visual deficit, were all transient ischemic attacks, 6 in the target 3 group (1.8 per 100 patient-years) and 6 in the target 4 group (2.1 per 100 patient- years). There were 3 vascular deaths in each group (0.9 and 1 per 100 patient-years for target 3 and target 4 groups, respectively). Minor bleeding episodes occurred 85 times (26 per 100 patient-years) in the target 3 group and 123 times (43 per 100 patient-years) in the target 4 group (p = 0.001).Conclusions. Mechanical heart valve patients on anticoagulant treatment who had been operated on at least 6 months earlier experienced fewer bleeding complications when maintained on a moderate intensity regimen (target INR = 3) than those on a moderate-high intensity regimen (target INR = 4). The number of thromboembolic events and vascular deaths did not differ between the two groups.

Long-term anticoagulation self-testing after mechanical heart valve replacement

2007 ◽  
Vol 55 (S 1) ◽  
Author(s):  
H Mair ◽  
B Reichart ◽  
I Kaczmarek ◽  
G Juchem ◽  
P Überfuhr ◽  
...  
Keyword(s):  
Valve Replacement ◽  
Heart Valve ◽  
Mechanical Heart Valve ◽  
Heart Valve Replacement ◽  
Self Testing
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