scholarly journals Tart Cherry Supplementation and Recovery From Strenuous Exercise: A Systematic Review and Meta-Analysis

2020 ◽  
pp. 1-14
Author(s):  
Jessica Amie Hill ◽  
Karen Mary Keane ◽  
Rebecca Quinlan ◽  
Glyn Howatson
Keyword(s):  
Muscular Strength ◽  
Muscle Soreness ◽  
Meta Analysis ◽  
Strenuous Exercise ◽  
Tart Cherry ◽  
C Reactive Protein ◽  
Necrosis Factor Alpha ◽  
Reactive Protein ◽  
Factor Alpha ◽  
Necrosis Factor

The aim of this study was to determine the efficacy of tart cherry (TC) supplementation on recovery following strenuous exercise. A systematic review and meta-analysis were conducted using studies investigating TC supplementation on measures of muscle soreness, muscular strength, muscular power, creatine kinase, C-reactive protein, Interleukin-6, and tumor necrosis factor alpha. A literature search ending in July 2020 was conducted in three databases (SPORTDiscus, Web of Science, and PubMed). Data from 14 studies were extracted and pooled for analysis. Tart cherry supplementation had a small beneficial effect in reducing muscle soreness (effect size [ES] = −0.44, 95% confidence interval [CI] [−0.87, −0.02]). A moderate beneficial effect was observed for recovery of muscular strength (ES = −0.78, 95% CI [−1.11, −0.46]). A moderate effect was observed for muscular power (ES = −0.53, 95% CI [−0.77, −0.29]); a further subgroup analysis on this variable indicated a large effect of TC supplementation on recovery of jump height (ES = −0.82, 95% CI [−1.18, −0.45]) and a small significant effect of supplementation on sprint time (ES = −0.32, 95% CI [−0.60, −0.04]). A small effect was observed for both C-reactive protein (ES = −0.46, 95% CI [−0.93, −0.00]) and Interleukin-6 (ES = −0.35, 95% CI [−0.68, −0.02]. No significant effects were observed for creatine kinase and tumor necrosis factor alpha. These results indicate that the consumption of a TC supplement can aid aspects of recovery from strenuous exercise.

Effects of concurrent training on interleukin-6, tumour necrosis factor-alpha and C-reactive protein in middle-aged men

2011 ◽  
Vol 29 (14) ◽  
pp. 1573-1581 ◽  
Author(s):  
Cleiton Augusto Libardi ◽  
Giovana Verginia Souza ◽  
Arthur Fernandes GÁspari ◽  
Claudinei Ferreira Dos Santos ◽  
Sabrina Toffoli Leite ◽  
...  
Keyword(s):  
Tumour Necrosis Factor ◽  
Interleukin 6 ◽  
Tumour Necrosis ◽  
Tumour Necrosis Factor Alpha ◽  
Concurrent Training ◽  
C Reactive Protein ◽  
Necrosis Factor Alpha ◽  
Reactive Protein ◽  
Factor Alpha ◽  
Necrosis Factor

scholarly journals Association of Tumor Necrosis Factor Alpha, Interleukin 6, and C-Reactive Protein with the Risk of Developing Type 2 Diabetes: A Retrospective Cohort Study of Rural Thais

2019 ◽  
Vol 2019 ◽  
pp. 1-9 ◽  
Author(s):  
Jirayu Lainampetch ◽  
Pornpimol Panprathip ◽  
Chanchira Phosat ◽  
Noppanath Chumpathat ◽  
Pattaneeya Prangthip ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Tumor Necrosis Factor ◽  
Tumor Necrosis ◽  
Inflammatory Marker ◽  
C Reactive Protein ◽  
Necrosis Factor Alpha ◽  
Reactive Protein ◽  
Factor Alpha ◽  
Necrosis Factor

The linkage of obesity, inflammation, and type 2 diabetes mellitus (T2DM) has been extensively investigated for over a decade. However, the association between inflammatory biomarkers, including C-reactive protein (CRP), interleukin 6 (IL-6), and tumor necrosis factor alpha (TNF-α), and T2DM is still inconsistent and limited. Thus, this study is aimed at elucidating the association between inflammatory marker levels and the risk of developing T2DM in many aspects. Among 296 subjects enrolled in 2013, 248 non-T2DM subjects who were completely reinvestigated in 2014 and 2015 were included in a 2-year retrospective analysis. Multivariate logistic regression was performed to evaluate the association of baseline inflammatory marker levels and variation with incidence of T2DM. After the 2-year follow-up, 18.6% of total subjects had developed T2DM. The risk of developing T2DM was significantly increased in subjects with a high level of baseline CRP (OR=4.02, 95% CI: 1.77-9.12, P=0.001), and a stronger impact was found with the combination of high CRP and IL-6 levels (OR=5.11, 95% CI: 1.27-20.49, P=0.021). One-year inflammatory marker variation analysis also revealed the significant association of elevated TNF-α and risk of developing T2DM (OR=4.88, 95% CI: 1.01-23.49, P=0.048). In conclusion, besides consideration of CRP levels alone, our findings suggested that IL-6 outstandingly plays a contributing role in T2DM progression and elevated TNF-α levels over time could be a potential predictor of T2DM.

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