Oral Presence of Carbohydrate and Caffeine in Chewing Gum: Independent and Combined Effects on Endurance Cycling Performance

2016 ◽  
Vol 11 (2) ◽  
pp. 164-171 ◽  
Author(s):  
Katherine T. Oberlin-Brown ◽  
Rodney Siegel ◽  
Andrew E. Kilding ◽  
Paul B. Laursen

The oral presence of carbohydrate (CHO) and caffeine (CAF) may independently enhance exercise performance, but their influence on performance during prolonged exercise is less known.Aim:To determine the independent and combined effects of CHO and CAF administered in chewing gum during a cycling time trial (TT) after prolonged exercise.Method:Eleven male cyclists (32.2 ± 7.5 y, 74.3 ± 6.8 kg, 60.2 ± 4.0 mL · kg–1 · min–1 V˙O2peak) performed 4 experimental trials consisting of 90-min constant-load cycling at 80% of their second ventilatory threshold (207 ± 30 W), followed immediately by a 20-km TT. Under double-blinded conditions, cyclists received placebo (PLA), CHO, CAF, or a combined CHO+CAF chewing gum at 0-, 5-, 10-, and 15-km points of the TT.Results:Overall TT performance was similar across experimental and PLA trials (%mean difference ± 90%CL 0.2% ± 2.0%, 0.4% ± 2.2%, 0.1% ± 1.8% for CHO, CAF, and CHO+CAF). Compared with PLA, mean power output tended to be higher in the first 2 quarters of the TT with CHO (1.6% ± 3.1% and 0.8% ± 2.0%) and was substantially improved in the last 2 quarters during CAF and CHO+CAF trials (4.2% ± 3.0% and 2.0% ± 1.8%). There were no differences in average heart rate (ES <0.2) and only small changes in blood glucose (ES 0.2), which were unrelated to performance. Blood lactate was substantially higher post-TT for CAF and CHO+CAF (ES >0.6).Conclusion:After prolonged constant-load cycling, the oral presence of CHO and CAF in chewing gum, independently or in combination, did not improve overall performance but did influence pacing.

2015 ◽  
Vol 25 (3) ◽  
pp. 285-292 ◽  
Author(s):  
Michael L. Newell ◽  
Angus M. Hunter ◽  
Claire Lawrence ◽  
Kevin D. Tipton ◽  
Stuart D. R. Galloway

In an investigator-blind, randomized cross-over design, male cyclists (mean± SD) age 34.0 (± 10.2) years, body mass 74.6 (±7.9) kg, stature 178.3 (±8.0) cm, peak power output (PPO) 393 (±36) W, and VO2max 62 (±9) ml·kg−1min−1 training for more than 6 hr/wk for more than 3y (n = 20) completed four experimental trials. Each trial consisted of a 2-hr constant load ride at 95% of lactate threshold (185 ± 25W) then a work-matched time trial task (~30min at 70% of PPO). Three commercially available carbohydrate (CHO) beverages, plus a control (water), were administered during the 2-hr ride providing 0, 20, 39, or 64g·hr−1 of CHO at a fluid intake rate of 1L·hr−1. Performance was assessed by time to complete the time trial task, mean power output sustained, and pacing strategy used. Mean task completion time (min:sec ± SD) for 39g·hr−1 (34:19.5 ± 03:07.1, p = .006) and 64g·hr−1 (34:11.3 ± 03:08.5 p = .004) of CHO were significantly faster than control (37:01.9 ± 05:35.0). The mean percentage improvement from control was −6.1% (95% CI: −11.3 to −1.0) and −6.5% (95% CI: −11.7 to −1.4) in the 39 and 64g·hr−1 trials respectively. The 20g·hr−1 (35:17.6 ± 04:16.3) treatment did not reach statistical significance compared with control (p = .126) despite a mean improvement of −3.7% (95% CI −8.8−1.5%). No further differences between CHO trials were reported. No interaction between CHO dose and pacing strategy occurred. 39 and 64g·hr−1 of CHO were similarly effective at improving endurance cycling performance compared with a 0g·hr−1 control in our trained cyclists.


2014 ◽  
Vol 24 (5) ◽  
pp. 507-515 ◽  
Author(s):  
Adam B. Schroer ◽  
Michael J. Saunders ◽  
Daniel A. Baur ◽  
Christopher J. Womack ◽  
Nicholas D. Luden

Previous studies reported that adding protein (PRO) to carbohydrate (CHO) solutions enhances endurance performance. The ergogenic effect may be a function of additional protein/amino acid calories, but this has not been examined. In addition, although supplemental L-alanine (ALA) is readily oxidized during exercise, the subsequent impact on metabolism and prolonged endurance performance is unknown. The purpose of this investigation was to independently gauge the impact of whey PRO hydrolysate and ALA supplementation on performance and various physiological parameters. Eight cyclists (age: 22.3 ± 5.6 yr, weight: 70.0 ± 8.0 kg, VO2max: 59.4 ± 4.9 ml·kg−1·min−1) performed 120 min of constant-load cycling (55% of peak power) followed by a 30-km time trial (TT) under placebo (PLA), PRO, and ALA conditions. Magnitude-based qualitative inferences were applied to evaluate treatment differences and data are presented as percent difference between treatments ± 90% confidence limit. Both ALA (–2.1 ± 2.7%) and PRO intake (–2.1 ± 2.2%) possibly harmed performance compared with PLA. Of interest, heart rate was possibly lower with ALA than PLA at 20– (–2.7 ± 3.4%) and 120-min (–1.7 ± 2.9%) of constant-load cycling and the serum interleukin-6 (IL-6) response to 120 min of cycling was likely attenuated with PRO compared with PLA (PLA, 6.6 ± 3.7 fold vs. PRO, 2.9 ± 1.8 fold). In addition, blood glucose levels were lower with PRO than PLA at 20– (–8.8 ± 2.3%; very likely) and 120-min (–4.9 ± 4.6%; likely) of constant-load cycling. Although ALA intake appears to lower HR and PRO ingestion dampens the IL-6 response to exercise, the ingestion of PRO (without CHO) or ALA does not enhance, and may actually impair, performance following prolonged cycling.


2014 ◽  
Vol 9 (2) ◽  
pp. 309-315 ◽  
Author(s):  
Gregory T. Levin ◽  
Paul B. Laursen ◽  
Chris R. Abbiss

Purpose:To assess the reliability of a 5-min-stage graded exercise test (GXT) and determine the association between physiological attributes and performance over stochastic cycling trials of varying distance.Methods:Twenty-eight well-trained male cyclists performed 2 GXTs and either a 30-km (n = 17) or a 100-km stochastic cycling time trial (n = 9). Stochastic cycling trials included periods of high-intensity efforts for durations of 250 m, 1 km, or 4 km depending on the test being performing.Results:Maximal physiological attributes were found to be extremely reliable (maximal oxygen uptake [VO2max]: coefficient of variation [CV] 3.0%, intraclass correlation coefficient [ICC] .911; peak power output [PPO]: CV 3.0%, ICC .913), but a greater variability was found in ventilatory thresholds and economy. All physiological variables measured during the GXT, except economy at 200 W, were correlated with 30-km cycling performance. Power output during the 250-m and 1-km efforts of the 30-km trial were correlated with VO2max, PPO, and the power output at the second ventilatory threshold (r = .58–.82). PPO was the only physiological attributed measured during the GXT to be correlated with performance during the 100-km cycling trial (r = .64).Conclusions:Many physiological variables from a reliable GXT were associated with performance over shorter (30-km) but not longer (100-km) stochastic cycling trials.


Author(s):  
Marcus J. Callahan ◽  
Evelyn B. Parr ◽  
John A. Hawley ◽  
Louise M. Burke

When ingested alone, beetroot juice and sodium bicarbonate are ergogenic for high-intensity exercise performance. This study sought to determine the independent and combined effects of these supplements. Eight endurance trained (VO2max 65 mL·kg·min-1) male cyclists completed four × 4-km time trials (TT) in a doubleblind Latin square design supplementing with beetroot crystals (BC) for 3 days (15 g·day-1 + 15 g 1 h before TT, containing 300 mg nitrate per 15 g), bicarbonate (Bi 0.3 g·kg-1 body mass [BM] in 5 doses every 15 min from 2.5 h before TT); BC+Bi or placebo (PLA). Subjects completed TTs on a Velotron cycle ergometer under standardized laboratory conditions. Plasma nitrite concentrations were significantly elevated only in the BC+Bi trial before the TT (1520 ± 786 nmol·L-1) compared with baseline (665 ± 535 nmol·L-1, p = .02) and the Bi and PLA conditions (Bi: 593 ± 203 nmol·L-1, p < .01; PLA: 543 ± 369 nmol·L-1, p < .01). Plasma nitrite concentrations were not elevated in the BC trial before the TT (1102 ± 218 nmol·L-1) compared with baseline (975 ± 607 nmol·L-1, p > .05). Blood bicarbonate concentrations were increased in the BC+Bi and Bi trials before the TT (BC+Bi: 30.9 ± 2.8 mmol·L-1; Bi: 31.7 ± 1.1 mmol·L-1). There were no differences in mean power output (386–394 W) or the time taken to complete the TT (335.8–338.1 s) between any conditions. Under the conditions of this study, supplementation was not ergogenic for 4-km TT performance.


2020 ◽  
Vol 15 (8) ◽  
pp. 1095-1102
Author(s):  
Alfred Nimmerichter ◽  
Bernhard Prinz ◽  
Matthias Gumpenberger ◽  
Sebastian Heider ◽  
Klaus Wirth

Purpose: To evaluate the predictive validity of critical power (CP) and the work above CP (W′) on cycling performance (mean power during a 20-min time trial; TT20). Methods: On 3 separate days, 10 male cyclists completed a TT20 and 3 CP and W′ prediction trials of 1, 4, and 10 min and 2, 7, and 12 min in field conditions. CP and W′ were modeled across combinations of these prediction trials with the hyperbolic, linear work/time, and linear power inverse-time (INV) models. The agreement and the uncertainty between the predicted and actual TT20 were assessed with 95% limits of agreement and a probabilistic approach, respectively. Results: Differences between the predicted and actual TT20 were “trivial” for most of the models if the 1-min trial was not included. Including the 1-min trial in the INV and linear work/time models “possibly” to “very likely” overestimated TT20. The INV model provided the smallest total error (ie, best individual fit; 6%) for all cyclists (305 [33] W; 19.6 [3.6] kJ). TT20 predicted from the best individual fit-derived CP, and W′ was strongly correlated with actual TT20 (317 [33] W; r = .975; P < .001). The bias and 95% limits of agreement were 4 (7) W (−11 to 19 W). Conclusions: Field-derived CP and W′ accurately predicted cycling performance in the field. The INV model was most accurate to predict TT20 (1.3% [2.4%]). Adding a 1-min-prediction trial resulted in large total errors, so it should not be included in the models.


2009 ◽  
Vol 19 (3) ◽  
pp. 275-284 ◽  
Author(s):  
Carl J. Hulston ◽  
Asker E. Jeukendrup

The purpose of this study was to investigate the possibility of a placebo effect from carbohydrate (CHO) intake during prolonged exercise. Ten endurance-trained male cyclists performed 3 experimental trials consisting of 120 min of steady-state cycling at 61% VO2max followed by a time trial (TT) lasting approximately 60 min. During exercise participants ingested either plain water (WAT), artificially colored and flavored water (PLA), or a 6% carbohydrate-electrolyte solution (CES). PLA and CES were produced with identical color and taste. To investigate the possibility of a placebo effect from CHO intake, participants were told that both flavored solutions contained CHO and that the purpose of the study was to compare CHO drinks with water. Mean power output during TT was 218 ± 22 W in WAT, 219 ± 17 W in PLA, and 242 ± 27 W in CES. Performance times were 66.35 ± 6.15, 65.94 ± 5.56, and 59.69 ± 2.87 min for WAT, PLA, and CES, respectively. Therefore, CES ingestion enhanced TT performance by 11.3% compared with WAT (p < .05) and 10.6% compared with PLA (p < .05), with no difference between PLA and WAT. In conclusion, during a prolonged test of cycling performance, in which participants were not fully informed of the test conditions, there was no placebo effect when participants believed they had ingested CHO. In contrast, the real effect of CHO intake was a 10.6% improvement in TT cycling performance.


2012 ◽  
Vol 22 (3) ◽  
pp. 175-183 ◽  
Author(s):  
Andrew E. Kilding ◽  
Claire Overton ◽  
Jonathan Gleave

Purpose:To determine the effects of ingesting caffeine (CAFF) and sodium bicarbonate (SB), taken individually and simultaneously, on 3-km cycling time-trial (TT) performance.Method:Ten well-trained cyclists, age 24.2 ± 5.4 yr, participated in this acute-treatment, double-blind, crossover study that involved four 3-km cycling TTs performed on separate days. Before each TT, participants ingested either 3 mg/kg body mass (BM) of CAFF, 0.3 g · kg−1 · BM−1 of SB, a combination of the two (CAFF+SB), or a placebo (PLAC). They completed each 3-km TT on a laboratory-based cycle ergometer, during which physiological, perceptual, and performance measurements were determined. For statistical analysis, the minimal worthwhile difference was considered ~1% based on previous research.Results:Pretrial pH and HCO3 were higher in SB and CAFF+SB than in the CAFF and PLAC trials. Differences across treatments for perceived exertion and gastric discomfort were mostly unclear. Compared with PLAC, mean power output during the 3-km TT was higher in CAFF, SB, and CAFF+SB trials (2.4%, 2.6%, 2.7% respectively), resulting in faster performance times (–0.9, –1.2, –1.2% respectively). Effect sizes for all trials were small (0.21–0.24).Conclusions:When ingested individually, both CAFF and SB enhance high-intensity cycling TT performance in trained cyclists. However, the ergogenic effect of these 2 popular supplements was not additive, bringing into question the efficacy of coingesting the 2 supplements before short-duration high-intensity exercise. In this study there were no negative effects of combining CAFF and SB, 2 relatively inexpensive and safe supplements.


2019 ◽  
Vol 14 (6) ◽  
pp. 727-732
Author(s):  
Naroa Etxebarria ◽  
Megan L. Ross ◽  
Brad Clark ◽  
Louise M. Burke

Purpose: The authors investigated the potential benefit of ingesting 2 mM of quinine (bitter tastant) on a 3000-m cycling time-trial (TT) performance. Methods: Nine well-trained male cyclists (maximal aerobic power: 386 [38] W) performed a maximal incremental cycling ergometer test, three 3000-m familiarization TTs, and four 3000-m intervention TTs (∼4 min) on consecutive days. The 4 interventions were (1) 25 mL of placebo, (2) a 25-mL sweet solution, and (3) and (4) repeat 25 mL of 2-mM quinine solutions (Bitter1 and Bitter2), 30 s before each trial. Participants self-selected their gears and were only aware of distance covered. Results: Overall mean power output for the full 3000 m was similar for all 4 conditions: placebo, 348 (45) W; sweet, 355 (47) W; Bitter1, 354 (47) W; and Bitter2, 355 (48) W. However, quinine administration in Bitter1 and Bitter2 increased power output during the first kilometer by 15 ± 11 W and 21 ± 10 W (mean ± 90% confidence limits), respectively, over placebo, followed by a decay of 34 ± 32 W during Bitter1 and Bitter2 during the second kilometer. Bitter2 also induced a 11 ± 13-W increase during the first kilometer compared with the sweet condition. Conclusions: Ingesting 2 mM of quinine can improve cycling performance during the first one-third of a 3000-m TT and could be used for sporting events lasting ∼80 s to potentially improve overall performance.


2020 ◽  
Vol 34 (3) ◽  
pp. 471-481
Author(s):  
Gabriel Barreto ◽  
Rafael Pires da Silva ◽  
Guilherme Yamaguchi ◽  
Luana Farias de Oliveira ◽  
Vitor de Salles Painelli ◽  
...  

Caffeine has been shown to increase anaerobic energy contribution during short-duration cycling time-trials (TT) though no information exists on whether caffeine alters energy contribution during more prolonged, aerobic type TTs. The aim of this study was to determine the effects of caffeine supplementation on longer and predominantly aerobic exercise. Fifteen recreationally-trained male cyclists (age 38±8 y, height 1.76±0.07 m, body mass 72.9±7.7 kg) performed a ~30 min cycling TT following either 6 mg·kg-1BM caffeine (CAF) or placebo (PLA) supplementation, and one control (CON) session without supplementation, in a double- -blind, randomised, counterbalance and cross-over design. Mean power output (MPO) was recorded as the outcome measure. Respiratory values were measured throughout exercise for the determination of energy system contribution. Data were analysed using mixed-models. CAF improved mean MPO compared to CON (P=0.01), and a trend towards an improvement compared to PLA (P=0.07); there was no difference in MPO at any timepoint throughout the exercise between conditions. There was a main effect of Condition (P=0.04) and Time (P<0.0001) on blood lactate concentration, which tended to be higher in CAF vs. both PLA and CON (Condition effect, both P=0.07). Ratings of perceived exertion increased over time (P<0.0001), with no effect of Condition or interaction (both P>0.05). Glycolytic energy contribution was increased in CAF compared to CON and PLA (both P<0.05), but not aerobic or ATP-CP (both P>0.05). CAF improved aerobic TT performance compared to CON, which could be explained by increased glycolytic energy contribution.


2006 ◽  
Vol 16 (4) ◽  
pp. 405-419 ◽  
Author(s):  
Holden S-H. MacRae ◽  
Kari M. Mefferd

We investigated whether 6 wk of antioxidant supplementation (AS) would enhance 30 km time trial (TT) cycling performance. Eleven elite male cyclists completed a randomized, double-blind, cross-over study to test the effects of twice daily AS containing essential vitamins plus quercetin (FRS), and AS minus quercetin (FRS-Q) versus a baseline TT (B). MANOVA analysis showed that time to complete the 30 km TT was improved by 3.1% on FRS compared to B (P ≤ 0.01), and by 2% over the last 5 km (P ≤ 0.05). Absolute and relative (%HRmax) heart rates and percent VO2max were not different between trials, but average and relative power (% peak power) was higher on FRS (P ≤ 0.01). Rates of carbohydrate and fat oxidation were not different between trials. Thus, FRS supplementation significantly improved high-intensity cycling TT performance through enhancement of power output. Further study is needed to determine the potential mechanism(s) of the antioxidant efficacy.


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