Association of Habitual Physical Activity With Cardiovascular Risk Factors and Target Organ Damage in Adolescents and Young Adults

2018 ◽  
Vol 15 (3) ◽  
pp. 176-182 ◽  
Author(s):  
Samuel G. Wittekind ◽  
Nicholas M. Edwards ◽  
Philip R. Khoury ◽  
Connie E. McCoy ◽  
Lawrence M. Dolan ◽  
...  
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Young Adults ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Target Organ Damage ◽  
Organ Damage ◽  
Target Organ ◽  
Habitual Physical Activity ◽  
Adolescents And Young Adults

METABOLIC SYNDROME PER SE SIGNIFICANTLY INCREASES TARGET ORGAN DAMAGE IN SUBJECTS WITHOUT OVERT CARDIOVASCULAR RISK FACTORS

2008 ◽  
Vol 19 ◽  
pp. S48
Author(s):  
Davide Grassi ◽  
Cristina Lippi ◽  
Stefano Necozione ◽  
Monica Michetti ◽  
Azzurra D'Aurelio ◽  
...  
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Target Organ Damage ◽  
Organ Damage ◽  
Target Organ ◽  
Per Se

Target organ damage and control of cardiovascular risk factors in hypertensive patients

Herz ◽  
2015 ◽  
Vol 40 (S2) ◽  
pp. 209-216 ◽  
Author(s):  
R.K. Reibis ◽  
M. Huber ◽  
M. Karoff ◽  
W. Kamke ◽  
R. Kreutz ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Target Organ Damage ◽  
Organ Damage ◽  
Target Organ ◽  
Hypertensive Patients ◽  
And Control

Blood pressure variability predicts cardiovascular events independently of traditional cardiovascular risk factors and target organ damage

2015 ◽  
Vol 33 (12) ◽  
pp. 2422-2430 ◽  
Author(s):  
Julie K.K. Vishram ◽  
Björn Dahlöf ◽  
Richard B. Devereux ◽  
Hans Ibsen ◽  
Sverre E. Kjeldsen ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Cardiovascular Events ◽  
Blood Pressure Variability ◽  
Target Organ Damage ◽  
Organ Damage ◽  
Target Organ

scholarly journals Association of VAV2 and VAV3 polymorphisms with cardiovascular risk factors

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Nuria Perretta-Tejedor ◽  
Javier Fernández-Mateos ◽  
Luis García-Ortiz ◽  
Manuel A. Gómez-Marcos ◽  
José I. Recio-Rodríguez ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Target Organ Damage ◽  
Ankle Brachial Index ◽  
Organ Damage ◽  
Target Organ ◽  
Nucleotide Exchange ◽  
Rac Gtpase ◽  
Increased Risk

Abstract Hypertension, diabetes and obesity are cardiovascular risk factors closely associated to the development of renal and cardiovascular target organ damage. VAV2 and VAV3, members of the VAV family proto-oncogenes, are guanosine nucleotide exchange factors for the Rho and Rac GTPase family, which is related with cardiovascular homeostasis. We have analyzed the relationship between the presence of VAV2 rs602990 and VAV3 rs7528153 polymorphisms with cardiovascular risk factors and target organ damage (heart, vessels and kidney) in 411 subjects. Our results show that being carrier of the T allele in VAV2 rs602990 polymorphism is associated with an increased risk of obesity, reduced levels of ankle-brachial index and diastolic blood pressure and reduced retinal artery caliber. In addition, being carrier of T allele is associated with increased risk of target organ damage in males. On the other hand, being carrier of the T allele in VAV3 rs7528153 polymorphism is associated with a decreased susceptibility of developing a pathologic state composed by the presence of hypertension, diabetes, obesity or cardiovascular damage, and with an increased risk of developing altered basal glycaemia. This is the first report showing an association between VAV2 and VAV3 polymorphisms with cardiovascular risk factors and target organ damage.

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