Effectiveness of Continuous Aerobic Versus High-Intensity Interval Training on Atherosclerotic and Inflammatory Markers in Boys With Overweight/Obesity

2020 ◽  
pp. 1-7
Author(s):  
Alireza Paahoo ◽  
Vahid Tadibi ◽  
Nasser Behpoor

Purpose: Atherosclerosis is a complex multifactorial disease whose first steps can be initiated from childhood. Therefore, we examined the effects of 2 training models on salusins levels, inflammatory markers, and lipid profile in boys with overweight/obesity. Method: Forty-five boys with overweight/obesity with the mean age of 11.06 (1.0) years were randomly divided into three groups of 15: a high-intensity interval training (HIIT) group (100%–110% of maximum aerobic speed); an aerobic training group (40%–70% of heart rate reserve); and a control group. The intervention included 3 sessions per week for 12 weeks. Results: Findings showed significant improvements in serum levels of salusins, salusins ratio, interleukin-6 (IL-6), and total cholesterol (TC) in both training groups (P < .001). Also, the serum levels of C-reactive protein (CRP), triglycerides (TG), low-density lipoprotein cholesterol (LDL), high-density lipoprotein cholesterol (HDL), atherogenic index of plasma (AIP), and cholesterol index improved significantly (P < .01). Except for the TG, HIIT caused higher improvements than aerobic training (P < .001 for salusin-α, salusins ratio, IL-6, CRP, TC, HDL, AIP, and cholesterol index; and P < .01 for salusin-β and LDL). Conclusion: The present study shows that HIIT has more positive effects than aerobic exercise on the atherosclerotic and inflammatory factors, as well as lipid profile variables in children with overweight/obesity.

2021 ◽  
Vol 27 (1) ◽  
pp. 159-168
Author(s):  
Nazhif Gifari ◽  
◽  
Hardinsyah Hardinsyah ◽  
Drajat Martianto ◽  
Mary Kuswari ◽  
...  

Introduction: Obesity and overweight in adolescents and adults are associated with chronic diseases. The objective of this study was to determine the effect of high-intensity interval training and pre-meal water intake on the lipid profile of overweight and obese students. Methods: This was a pre-post experimental study. Twenty-seven overweight and obese students (mean BMI 26.0±3.1 kg/m2 and mean age 19.7±0.7 years) were divided randomly into three groups. The first group (n=9; BMI=26.6±3.6 kg/m2) received Plain Water Intake (PWI) intervention, whereby students received three bottles of plain water (600 mL) per mealtime (total 1.8 L/ day) and consumed ad libitum 30 to 45 minutes before mealtime (breakfast, lunch, and dinner). The second group (n=9; BMI=25.9±2.4 kg/m2) received High-Intensity Interval Training (HIIT) intervention and underwent three exercise sessions per week (18 minutes/day; 70–85% of HRmax) that was introduced through a video recording. The last group (n=9; BMI= 25.7±3.4 kg/m2) received a combination of PWI+HIIT intervention. Nutritional status, nutrient intake, and lipid profile [total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C)] were assessed before and after the interventions. Data were analysed using paired sample t-test and Analysis of Variance (ANOVA). Results: The PWI group showed a significant increase in HDL-C, while the HIIT group showed a significant reduction in TC (p<0.05). On the other hand, the PWI+HIIT group showed significant improvements in lipid profile (TC, TG and HDL-C) (p<0.05). Conclusion: A combination of PWI+HIIT intervention may be effective in improving lipid profile.


2011 ◽  
Vol 18 (6) ◽  
pp. 850-857 ◽  
Author(s):  
Peter Scott Munk ◽  
Unni Mathilde Breland ◽  
Pål Aukrust ◽  
Thor Ueland ◽  
Jan Terje Kvaløy ◽  
...  

Background: Increased plasma levels of inflammatory markers and markers of endothelial cell activation have been associated with increased risk for cardiovascular events. Exercise training may lower the risk for coronary heart disease by attenuating inflammation and improving endothelial function. The objective of this study was to evaluate effects of regular high-intensity exercise training on a wide range of markers of inflammation and endothelial cell activation. Materials and methods: Consecutively, 40 patients were prospectively randomized to a 6 months supervised high-intensity interval training programme or to a control group following successful percutaneous coronary intervention (PCI). Blood samples of 36 patients with stable angina, drawn at baseline (before PCI) and at 6 months, were analysed. Late luminal loss was measured at 6 months using quantitative coronary angiography. Results: At 6 months, levels of the inflammatory markers interleukin (IL)-6 and IL-8 were reduced and levels of the anti-inflammatory cytokine IL-10 increased in the training group only. The decrease in IL-6 and C-reactive protein levels were significantly correlated with the decrease in luminal loss following PCI. In contrast to these anti-inflammatory effects, training had no effect on markers of platelet-mediated inflammation, and the effect of training on markers on endothelial cell activation were rather complex showing attenuating (von Willebrand factor) and enhancing (E-selectin and vascular cell adhesion molecule 1) effects. Conclusions: Regular exercise training in stable angina patients following PCI may attenuate some, but not all, inflammatory pathways, potentially contributing to the beneficial effects of exercise training on restenosis.


Author(s):  
Sajad Ahmadizad ◽  
Alireza Salimi Avansar ◽  
Khosrow Ebrahim ◽  
Mohsen Avandi ◽  
Mansour Ghasemikaram

AbstractExercise training is an effective method of weight management, and knowing about its influence on the hormones involved in the regulation of food intake and inflammation could be useful for body weight management. Therefore, the purpose of this study was to compare the effects of 6 weeks of high-intensity interval training (HIIT) and moderate-intensity continuous exercise training (MCT) on nesfatin-1, interleukin (IL)-6, and tumor necrosis factor alpha (TNF-α).Thirty sedentary overweight men (Mean±SD; age, 25±1 years) were divided into three (n=10) body mass index-matched groups. The participants in the training groups performed either HIIT or MCT protocols 3 days per week for 6 weeks followed by a week of detraining.Plasma IL-6 and TNF-α did not significantly change after training, but nesfatin increased significantly only with HIIT compared with the control group (p<0.05). In addition, fasting glucose, insulin, and homeostasis model estimated insulin resistance (HOMA-IR), decreased significantly following both HIIT and MCT training (p<0.05). After a detraining period, the plasma nesfatin-1 did not return to pre-training levels in the HIIT group.Both the HIIT and MCT groups had similar effects on inflammatory markers and insulin resistance in men who are overweight, but the HIIT seems to have better anorectic effects (as indicated by nesfatin) compared with MCT.


2016 ◽  
Author(s):  
ALEXANDRE ETECHEBERE ◽  
MARA PATRICIA TRAINA CHACON MIKAHIL ◽  
ALEX CASTRO ◽  
MARCEL LOPES DOS SANTOS ◽  
ISABELLA RIGHI ◽  
...  

Dose-Response ◽  
2018 ◽  
Vol 16 (3) ◽  
pp. 155932581879701 ◽  
Author(s):  
Borja Sañudo ◽  
Tamara Muñoz ◽  
Gareth W. Davison ◽  
Guillermo Lopez-Lluch ◽  
Jesus del Pozo-Cruz

This study aimed to compare the effect of high-intensity interval training (HIIT) with additional whole-body vibration (WBV) on body composition and lipid profile in obese/overweight adults on a hypocaloric diet. Forty adults were randomly assigned to (a) HIIT and vibration and hypocaloric diet (HIITWBV, n = 13), (b) HIIT and diet (HIIT, n = 14), and (c) diet only (control [CON], n = 13). High-intensity interval training WBV participants trained 3 times per week for 8 weeks (6 sets × 1 minute of HIIT, cycling at 90% heart rate peak followed by 1 minute of interset vibration, at a frequency of 18 Hz increasing until 25 Hz with a peak-to-peak displacement of 4 mm. Training volume increased 1 set every 2 weeks until 10 sets). The HIIT group performed HIIT training followed by 2 minutes of passive recovery, while the CON continued with their daily activities combined with calorie restriction. Body composition (body fat and fat-free mass) and biochemical indices (glucose, total cholesterol, high-density lipoprotein cholesterol, and triglycerides) were determined. Following 8 weeks, body fat was significantly reduced by 7.5% and both triglycerides and total cholesterol decreased in the HIITWBV group only (−16.5% and −11.7% respectively). This study suggests that HIIT in combination with WBV and a hypocaloric diet can improve overall lipid profile in overweight/obese individuals.


2017 ◽  
Author(s):  
ALEXANDRE ETECHEBERE ◽  
MARA PATRICIA TRAINA CHACON MIKAHIL ◽  
ALEX CASTRO ◽  
CLAUDIA R CAVAGLIERI ◽  
MARCEL LOPES DOS SANTOS

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