Increasing Chloramphenicol Resistance in Streptococcus pneumoniae Isolates from Papua New Guinean Children with Acute Bacterial Meningitis
2011 ◽
Vol 55
(9)
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pp. 4454-4456
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Keyword(s):
ABSTRACTIn Papua New Guinean (PNG) children with acute bacterial meningitis (ABM), allHaemophilus influenzaeisolates were resistant to chloramphenicol. AlthoughStreptococcus pneumoniaeisolates had a median chloramphenicol MIC of 3 μg/ml, it was ≥4 μg/ml in 42.8%, and the likelihood of an area under the 24-hour concentration-time curve/MIC ratio of >100 h at a MIC of ≥4 μg/ml was approximately 50%. All isolates were ceftriaxone sensitive. These data support ceftriaxone rather than conventional chloramphenicol for all PNG children with suspected ABM.
2017 ◽
Vol 11
(2)
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pp. 9-16
2016 ◽
Vol 60
(9)
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pp. 5533-5538
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2015 ◽
Vol 60
(1)
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pp. 180-189
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2010 ◽
Vol 54
(10)
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pp. 4300-4305
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1999 ◽
Vol 56
(11)
◽
pp. 640-646
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Keyword(s):