Cloning and nucleotide sequence analysis of a gene encoding an OXA-derived beta-lactamase in Acinetobacter baumannii.
1997 ◽
Vol 41
(12)
◽
pp. 2757-2759
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Keyword(s):
A clinical strain of Acinetobacter baumannii (strain Ab41) that was resistant to all beta-lactam antibiotics tested except ceftazidime, ceftriaxone, ceftizoxime, and imipenem produced three beta-lactamases: a presumptive chromosomal cephalosporinase, a TEM-1-like beta-lactamase (pI 5.4), and a novel OXA-derived beta-lactamase named OXA-21 (pI 7.0). The gene encoding OXA-21 was located in an integron. The nucleotide sequence showed three mutations compared with the sequence of OXA-3, with two being silent; the nonsilent mutation generated a substitution of Ile-217 to Met.
1992 ◽
Vol 12
(1)
◽
pp. 47-62
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1996 ◽
Vol 40
(11)
◽
pp. 2488-2493
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1992 ◽
Vol 73
(10)
◽
pp. 2743-2750
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Keyword(s):
1986 ◽
Vol 29
(5)
◽
pp. 955-957
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Keyword(s):
2021 ◽
Vol 38
(3)
◽
pp. 301-304
1987 ◽
Vol 169
(11)
◽
pp. 5216-5223
◽
2002 ◽
Vol 50
(2)
◽
pp. 261-264
◽
Keyword(s):