Interstrain Variation in the Human Cytomegalovirus DNA Polymerase Sequence and Its Effect on Genotypic Diagnosis of Antiviral Drug Resistance
1999 ◽
Vol 43
(6)
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pp. 1500-1502
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Keyword(s):
ABSTRACT The polymerase (pol) coding sequence was determined for 40 independent clinical cytomegalovirus isolates sensitive to ganciclovir and foscarnet. Sequence alignments showed >98% interstrain homology and amino acid variation in only 4% of the 1,237 codons. Almost all variation occurred outside of conserved functional domains where resistance mutations have been identified.
2010 ◽
Vol 23
(4)
◽
pp. 689-712
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2010 ◽
Vol 54
(12)
◽
pp. 5004-5011
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Keyword(s):
1994 ◽
Vol 38
(2)
◽
pp. 268-274
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Keyword(s):
2020 ◽
2018 ◽
Vol 16
(2)
◽
pp. 80-95
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1998 ◽
Vol 11
(1)
◽
pp. 51-60
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Keyword(s):