Δ12-Prostaglandin J2 Is a Potent Inhibitor of Influenza A Virus Replication
2000 ◽
Vol 44
(1)
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pp. 200-204
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Keyword(s):
ABSTRACT 9-Deoxy-Δ9,Δ12-13,14-dihydro-prostaglandin D2 (Δ12-PGJ2), a natural cyclopentenone metabolite of prostaglandin D2, is shown to possess therapeutic efficacy against influenza A virus A/PR8/34 (H1N1) infection in vitro and in vivo. The results indicate that the antiviral activity is associated with induction of cytoprotective heat shock proteins and suggest novel strategies for treatment of influenza virus infection.
Keyword(s):
2010 ◽
Vol 54
(8)
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pp. 3442-3450
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Keyword(s):
2012 ◽
Vol 93
(3)
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pp. 555-559
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Keyword(s):
1999 ◽
Vol 73
(4)
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pp. 3473-3476
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Keyword(s):