Isolation of Rhodococcus sp. Strain ECU0066, a New Sulfide Monooxygenase-Producing Strain for Asymmetric Sulfoxidation
2008 ◽
Vol 75
(2)
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pp. 551-556
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Keyword(s):
ABSTRACT A new and efficient sulfide monooxygenase-producing strain, ECU0066, was isolated and identified as a Rhodococcus sp. that could transform phenylmethyl sulfide (PMS) to (S)-sulfoxide with 99% enantiomeric excess via two steps of enantioselective oxidations. Its enzyme activity could be effectively induced by adding PMS or phenylmethyl sulfoxide (PMSO) directly to a rich medium at the early log phase (6 h) of fermentation, resulting in over 10-times-higher production of the enzyme. This bacterial strain also displayed fairly good activity and enantioselectivity toward seven other sulfides, indicating a good potential for practical application in asymmetric synthesis of chiral sulfoxides.
1995 ◽
Vol 50
(2)
◽
pp. 283-288
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Keyword(s):
1994 ◽
Vol 35
(29)
◽
pp. 5297-5300
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2017 ◽
Vol 15
(29)
◽
pp. 6098-6103
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Keyword(s):
2021 ◽
pp. 109-115
1994 ◽
Vol 35
(12)
◽
pp. 1937-1940
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