scholarly journals Evaluation of Serological Diagnostic Methods for the 2009 Pandemic Influenza A (H1N1) Virus

2011 ◽  
Vol 18 (3) ◽  
pp. 520-522 ◽  
Author(s):  
Jesse Papenburg ◽  
Mariana Baz ◽  
Marie-Ève Hamelin ◽  
Chantal Rhéaume ◽  
Julie Carbonneau ◽  
...  
Keyword(s):  
Reverse Transcriptase ◽  
Pandemic Influenza ◽  
Hemagglutination Inhibition ◽  
Influenza A ◽  
H1n1 Virus ◽  
Diagnostic Methods ◽  
Rt Pcr ◽  
Virus Diagnosis ◽  
Household Contacts ◽  
Influenza A H1n1

ABSTRACTSerology improves influenza diagnosis by capturing cases missed by reverse transcriptase PCR (RT-PCR). We prospectively evaluated microneutralization and hemagglutination inhibition assays for 2009 influenza A (H1N1) virus diagnosis among 24 RT-PCR-confirmed cases and 98 household contacts. Compared to hemagglutination inhibition, microneutralization demonstrated a higher level of concordance with RT-PCR (kappa = 0.69 versus kappa = 0.60) and greater sensitivity (83% versus 71%;P= 0.016).

Development of the real-time RT-PCR detection system for determination of pandemic influenza A (H1N1) virus

2011 ◽  
Vol 55 (1) ◽  
pp. 85-87 ◽  
Author(s):  
R. GAO ◽  
D. WANG ◽  
L. WEN ◽  
X. LI ◽  
W. WANG ◽  
...  
Keyword(s):  
Real Time ◽  
Pandemic Influenza ◽  
Influenza A ◽  
H1n1 Virus ◽  
Detection System ◽  
Pcr Detection ◽  
Rt Pcr ◽  
The Real ◽  
Influenza A H1n1

scholarly journals Ultrastructural and Histopathological Studies of 2009 Pandemic Influenza A (H1N1) Virus

2010 ◽  
Vol 16 (S2) ◽  
pp. 1122-1123
Author(s):  
CS Goldsmith ◽  
MG Metcalfe ◽  
W-J Shieh ◽  
DM Blau ◽  
DC Rollin ◽  
...  
Keyword(s):  
Pandemic Influenza ◽  
Influenza A ◽  
H1n1 Virus ◽  
Influenza A H1n1 ◽  
Histopathological Studies

Extended abstract of a paper presented at Microscopy and Microanalysis 2010 in Portland, Oregon, USA, August 1 – August 5, 2010.

scholarly journals Effects of Vaccine Program against Pandemic Influenza A(H1N1) Virus, United States, 2009–2010

2013 ◽  
Vol 19 (3) ◽  
Author(s):  
Rebekah H. Borse ◽  
Sundar S. Shrestha ◽  
Anthony E. Fiore ◽  
Charisma Y. Atkins ◽  
James A. Singleton ◽  
...  
Keyword(s):  
United States ◽  
Pandemic Influenza ◽  
Influenza A ◽  
H1n1 Virus ◽  
Influenza A H1n1

scholarly journals Influenza-Like Illness in a Community Surrounding a School-Based Outbreak of 2009 Pandemic Influenza A (H1N1) Virus-Chicago, Illinois, 2009

2010 ◽  
Vol 52 (Supplement 1) ◽  
pp. S94-S101 ◽  
Author(s):  
K. B. Janusz ◽  
J. E. Cortes ◽  
F. Serdarevic ◽  
R. C. Jones ◽  
J. D. Jones ◽  
...  
Keyword(s):  
Pandemic Influenza ◽  
Influenza A ◽  
H1n1 Virus ◽  
Influenza Like Illness ◽  
School Based ◽  
Influenza A H1n1

scholarly journals Seroprevalence study in Vojvodina (Serbia) following 2009 pandemic influenza A(H1N1)v

2012 ◽  
Vol 140 (11-12) ◽  
pp. 751-755
Author(s):  
Vladimir Petrovic ◽  
Zorica Seguljev ◽  
Jasminka Nedeljkovic ◽  
Mioljub Ristic
Keyword(s):  
Pandemic Influenza ◽  
Hemagglutination Inhibition ◽  
Influenza A ◽  
Herd Immunity ◽  
Age Groups ◽  
Immunization Coverage ◽  
Control Group ◽  
Study Objective ◽  
Seroprevalence Study ◽  
Influenza A H1n1

Introduction. The seroprevalence study was performed in Vojvodina during May and June 2010 in order to asses the effects of the 2009 pandemic influenza A(H1N1)v epidemic on herd immunity. It was a part of the Serbian Ministry of Health funded nationwide study. Objective. Prevalence of antibodies against 2009 pandemic influenza A(H1N1)v was determined in a 1% sample of the population monitored for influenza-like illness and acute respiratory infections in Vojvodina through sentinel surveillance system. Methods. The study sample involved a total of 1004 inhabitants of Vojvodina. The control group consisted of randomly selected and age-adjusted 1054 sera collected in the pre-pandemic period. Sera were tested by the reaction of hemagglutination inhibition using influenza A/California/7/2009 (H1N1) antigen in dilution from 1:8 to 1:256. Antibody titers ?1:32 and ?1:8 were considered protective and diagnostic, respectively. Results. The differences between control and study sera in all age groups were significant for both diagnostic ?1/8 and protective titres ?1/32 of hemagglutination inhibition antibodies (chi square test, p<0.001). The highest percentage of seropositive subjects was registered in the age group 15-19 years followed by children aged 5-14 years. Both diagnostic and protective titres were about twice higher in the vaccinated as compared to the non-vaccinated group. There were no statistically significant differences in seroprevalence between seven districts of Vojvodina. Conclusion. The 2009 pandemic influenza A(H1N1)v epidemic significantly influenced the herd immunity in our population regardless of low immunization coverage with highest immunity levels in adolescents aged 15-19 years and with similar herd immunity levels in all the regions in the province six months after the outbreak.

scholarly journals High prevalence of antibodies to the 2009 pandemic influenza A(H1N1) virus in the Norwegian population following a major epidemic and a large vaccination campaign in autumn 2009

2010 ◽  
Vol 15 (31) ◽  
Author(s):  
K Waalen ◽  
A Kilander ◽  
S G Dudman ◽  
G H Krogh ◽  
T Aune ◽  
...  
Keyword(s):  
Pandemic Influenza ◽  
Influenza A ◽  
H1n1 Virus ◽  
Vaccination Campaign ◽  
Age Group ◽  
Norwegian Population ◽  
Influenza A H1n1 ◽  
High Prevalence ◽  
Substantial Rise ◽  
Epidemic Wave

The prevalence of antibodies reactive to the 2009 pandemic influenza A(H1N1) was determined in sera collected before the start of the pandemic, during the early phase, and after the main epidemic wave and nationwide vaccination campaign in Norway. A substantial rise in prevalence of antibodies at protective titres, from 3.2% to 44.9%, was observed between August 2009 and January 2010. The highest prevalence, 65.3%, was seen in the age group of 10-19 year-olds.

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