scholarly journals Reference Ranges for Lymphocyte Subsets among Healthy Hong Kong Chinese Adults by Single-Platform Flow Cytometry

2013 ◽  
Vol 20 (4) ◽  
pp. 602-606 ◽  
Author(s):  
W. S. Wong ◽  
A. W. I. Lo ◽  
L. P. Siu ◽  
J. N. S. Leung ◽  
S. P. Tu ◽  
...  
Keyword(s):  
Flow Cytometry ◽  
Hong Kong ◽  
Clinical Decision Making ◽  
Lymphocyte Subsets ◽  
Local Population ◽  
Suppressor Cells ◽  
Clinical Decision ◽  
Hong Kong Chinese ◽  
Reference Ranges ◽  
Chinese Adults

ABSTRACTRace, age, sex, and environmental conditions have significant impacts on lymphocyte subset values. It is important to establish the local reference ranges from healthy and non-HIV-positive adults in the local population for clinical decision making. In this study, the reference ranges for lymphocyte subsets among Chinese adults were established by analysis by single-platform flow cytometry of the lymphocyte compositions of 273 healthy adult blood donors between 17 and 59 years of age. The 95% reference ranges for CD3+T cells, CD3+CD4+T helper cells, and CD3+CD8+T suppressor cells are 723 to 2,271 cells/μl, 396 to 1,309 cells/μl, and 224 to 1,014 cells/μl, respectively. The 95% reference ranges for CD19+B cells and CD56+NK cells are 118 to 645 cells/μl and 61 to 607 cells/μl, respectively. Significant gender and age differences in the lymphocyte subsets have been demonstrated. Our results have also shown that the T-lymphocyte compositions in Hong Kong Chinese were comparable to those of other Asian populations but were different from those of Caucasians.

Long-term outcomes and predictors of chronic insomnia: A prospective study in Hong Kong Chinese adults

2012 ◽  
Vol 13 (5) ◽  
pp. 455-462 ◽  
Author(s):  
Jihui Zhang ◽  
S.P. Lam ◽  
S.X. Li ◽  
M.W.M. Yu ◽  
A.M. Li ◽  
...  
Keyword(s):  
Hong Kong ◽  
Prospective Study ◽  
Hong Kong Chinese ◽  
Chronic Insomnia ◽  
Long Term Outcomes ◽  
Chinese Adults ◽  
A Prospective Study

Flow cytometry, cellular DNA content, and prognosis in human malignancy.

1987 ◽  
Vol 5 (10) ◽  
pp. 1690-1703 ◽  
Author(s):  
D E Merkel ◽  
L G Dressler ◽  
W L McGuire
Keyword(s):  
Flow Cytometry ◽  
Data Base ◽  
Dna Content ◽  
Dna Analysis ◽  
Clinical Decision Making ◽  
Risk Groups ◽  
Clinical Decision ◽  
Tumor Type ◽  
Cellular Dna ◽  
Bladder Carcinomas

The use of flow cytometry to analyze the cellular DNA content of human malignancies has become increasingly commonplace. The relationship between abnormalities in DNA content or proliferative characteristics and prognosis is becoming clear for a variety of malignancies in part through new techniques that permit analysis of archival material. High- and low-risk groups of patients with early breast and bladder carcinomas, non-small-cell lung cancer, and colorectal, ovarian, and cervical carcinoma can be distinguished on the basis of abnormal stemline DNA content. In several hematologic and common pediatric malignancies, the prognostic relevance of DNA content flow cytometry has been similarly established. Though the interpretation of tumor cell cycle analyses is less certain, this characteristic may also be prognostically important. However, generalizations cannot be made when applying flow cytometric DNA analysis to clinical decision making. The prognostic importance of an abnormal DNA histogram for an individual patient must be assessed on the basis of the relevant data base for that particular tumor type. The current extent of this data base for various malignancies is reviewed.

Socioeconomic disadvantages over the life-course and their influence on obesity among older Hong Kong Chinese adults

2020 ◽  
Vol 30 (5) ◽  
pp. 1013-1018 ◽  
Author(s):  
Gary K K Chung ◽  
Francisco T T Lai ◽  
Dicken C Chan ◽  
Hung Wong ◽  
Eng-Kiong Yeoh ◽  
...  
Keyword(s):  
Hong Kong ◽  
Life Course ◽  
Abdominal Obesity ◽  
Cumulative Risk ◽  
Hong Kong Chinese ◽  
Mobility Models ◽  
General Obesity ◽  
Chinese Adults ◽  
Socioeconomic Mobility ◽  
The Life Course

Abstract Background The life-course perspective on socioeconomic inequality in health is a burgeoning field of research. Nonetheless, the three classic life-course models (i.e. sensitive period, cumulative risk and social mobility models) have rarely been simultaneously applied to studies on obesity. Therefore, this study examined the associations of socioeconomic positions (SEPs) across life stages and their associated life-course models with both general and abdominal obesity. Methods Face-to-face interviews were conducted among 1077 community-dwelling adults aged 50 or above during 2014–15 in Hong Kong. Experiences of poverty, educational attainment and deprivation of necessities represented respondents’ SEP in childhood, early adulthood and late adulthood, respectively. General and abdominal obesity were defined as body mass index ≥25 kg m−2 and waist-to-height ratio >0.5. Multivariable modified Poisson regression with a robust error variance was performed. Results Respondents with low childhood SEP tended to have reduced risk of general obesity [relative risk (RR) = 0.85; 95% confidence interval (CI) = 0.72–1.00], whereas those with low childhood SEP and low late-adulthood SEP tended to have increased risk of abdominal obesity (RR = 1.10; 95% CI = 1.00–1.21 and RR = 1.14; 95% CI = 1.03–1.26, respectively). Cumulative socioeconomic disadvantages showed a dose–response relationship with abdominal obesity. Also, those with upward socioeconomic mobility had lower risk of abdominal obesity, whereas those with downward socioeconomic mobility had greater risk. Conclusions Low SEP, especially in childhood, exerted contrasting effects on general and abdominal obesity among older Hong Kong Chinese adults. The three life-course models operated simultaneously in determining the risk of abdominal obesity, while support for cumulative risk and social mobility models was weak in general obesity.

Comparing the Self-Concepts of Hong Kong Chinese Adults With Visible and Not Visible Physical Disability

2003 ◽  
Vol 137 (4) ◽  
pp. 363-372 ◽  
Author(s):  
Sing-Fai Tam ◽  
Mei Hing Chan ◽  
Hoi Wa Lam ◽  
Lai Hing Lam
Keyword(s):  
Hong Kong ◽  
Physical Disability ◽  
The Self ◽  
Hong Kong Chinese ◽  
Chinese Adults

scholarly journals Flow Cytometry To Assess Cerebrospinal Fluid Fungal Burden in Cryptococcal Meningitis

2015 ◽  
Vol 54 (3) ◽  
pp. 802-804 ◽  
Author(s):  
James E. Scriven ◽  
Lisa M. Graham ◽  
Charlotte Schutz ◽  
Thomas J. Scriba ◽  
Robert J. Wilkinson ◽  
...  
Keyword(s):  
Decision Making ◽  
Flow Cytometry ◽  
Cerebrospinal Fluid ◽  
Cryptococcal Meningitis ◽  
Clinical Decision Making ◽  
Important Determinant ◽  
Clinical Decision ◽  
Fungal Burden ◽  
Rapid Technique

Fungal burden in the cerebrospinal fluid is an important determinant of mortality in cryptococcal meningitis, but its use in aiding clinical decision making is hampered by the time involved to perform quantitative cultures. Here, we demonstrate the potential of flow cytometry as a novel and rapid technique to address this issue.

DEVELOPMENT AND VALIDATION OF A SELF-CONCEPT QUESTIONNAIRE FOR HONG KONG CHINESE ADULTS WHO HAVE PHYSICAL DISABILITY

1997 ◽  
Vol 25 (1) ◽  
pp. 1-11 ◽  
Author(s):  
Sing-Fai Tam ◽  
David Watkins
Keyword(s):  
Hong Kong ◽  
Physical Disability ◽  
Internal Consistency Reliability ◽  
The Self ◽  
Hong Kong Chinese ◽  
Self Concept ◽  
Chinese Adults ◽  
Concept Model ◽  
The Disabled ◽  
Development And Validation

Previous research (Tam & Watkins, 1995) provided an understanding of the self-concepts of Hong Kong Chinese adults who have physical disability. Through constructing a hierarchical multidimensional self-concept model for the disabled population, a theoretical basis was established for the development of a questionnaire to measure their self-concepts. Subsequent efforts focused on validating this instrument, the Self-Concept Questionnaire for Physically Disabled Hong Kong Chinese (SCQPD). The results provided evidence that this instrument is psychometrically sound. The scales have satisfactory internal consistency reliability and factor analysis of these scales makes conceptual sense. Some evidence for construct validity is also presented.

Polymorphisms in the IL-4, IL-4 Receptor α Chain, TNF-α, and Lymphotoxin-α Genes and Risk of Asthma in Hong Kong Chinese Adults

2007 ◽  
Vol 144 (2) ◽  
pp. 114-122 ◽  
Author(s):  
Judith C.W. Mak ◽  
Fanny W.S. Ko ◽  
Chung M. Chu ◽  
Helen C.M. Leung ◽  
Henry W. Chan ◽  
...  
Keyword(s):  
Hong Kong ◽  
Hong Kong Chinese ◽  
Chinese Adults ◽  
Tnf Α ◽  
Α Chain ◽  
Lymphotoxin Α
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