scholarly journals Plasmids coding for drug resistance and localized adherence to HeLa cells in enteropathogenic Escherichia coli O55:H- and O55:H6.

1986 ◽  
Vol 51 (2) ◽  
pp. 715-717 ◽  
Author(s):  
M Z Laporta ◽  
M L Silva ◽  
I C Scaletsky ◽  
L R Trabulsi
BMJ ◽  
1982 ◽  
Vol 285 (6340) ◽  
pp. 472-473 ◽  
Author(s):  
R J Gross ◽  
L R Ward ◽  
E J Threlfall ◽  
H King ◽  
B Rowe

2011 ◽  
Vol 5 (20) ◽  
pp. 3305-3309 ◽  
Author(s):  
Mitra Motallebi ◽  
Piroozm ◽  
Ahmad ◽  
Mehdi Rohani ◽  
Hosein Akbari ◽  
...  

1995 ◽  
Vol 18 (6) ◽  
pp. 387-399 ◽  
Author(s):  
Isabel C. Scaletsky ◽  
Silvia V.M. Gatti ◽  
Franco J. da Silveira ◽  
Iara M. DeLuca ◽  
Edna Freymuller ◽  
...  

2002 ◽  
Vol 70 (4) ◽  
pp. 2206-2209 ◽  
Author(s):  
Vlademir V. Cantarelli ◽  
Akira Takahashi ◽  
Itaru Yanagihara ◽  
Yukihiro Akeda ◽  
Kinichi Imura ◽  
...  

ABSTRACT Cortactin and the translocated intimin receptor, Tir, interacted with each other in pedestal formation in HeLa cells infected with enteropathogenic Escherichia coli (EPEC). Cortactin is shown to be necessary for organizing actin pedestals in response to EPEC, based on the expression of green fluorescent protein-fused cortactin derivatives in HeLa cells.


1998 ◽  
Vol 66 (4) ◽  
pp. 1755-1758 ◽  
Author(s):  
Goni Ben-Ami ◽  
Vered Ozeri ◽  
Emanuel Hanski ◽  
Fred Hofmann ◽  
Klaus Aktories ◽  
...  

ABSTRACT Enteropathogenic Escherichia coli (EPEC) induces formation of actin pedestals in infected host cells. Agents that inhibit the activity of Rho, Rac, and Cdc42, includingClostridium difficile toxin B (ToxB), compactin, and dominant negative Rho, Rac, and Cdc42, did not inhibit formation of actin pedestals. In contrast, treatment of HeLa cells with ToxB inhibited EPEC invasion. Thus, Rho, Rac, and Cdc42 are not required for assembly of actin pedestals; however, they may be involved in EPEC uptake by HeLa cells.


1989 ◽  
Vol 93 (3) ◽  
pp. 439-446
Author(s):  
M.L. da Silva ◽  
R.A. Mortara ◽  
H.C. Barros ◽  
W. de Souza ◽  
L.R. Trabulsi

We have previously observed that enteropathogenic Escherichia coli (EPEC) adhere to HeLa cells in a localized manner, which we designated localized adherence as opposed to the diffuse pattern of adhesion. In this paper we have examined the effects of localized adherence of EPEC on the actin microfilament system of host HeLa cells. Centrifugation of bacteria onto HeLa cells improved the localized adherence and rapid rearrangements of actin filaments were detected by immunofluorescence and electron microscopy. Aggregation of microfilaments is consistently observed at the sites of localized adherence, and is abolished by cytochalasin D and low temperatures. Scanning electron microscopy indicates that these aggregates are surface microvilli entangled with attached EPEC.


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