Identification of Schizosaccharomyces pombe transcription factor PGA4, which binds cooperatively to Saccharomyces cerevisiae GAL4-binding sites
1990 ◽
Vol 10
(4)
◽
pp. 1432-1438
Keyword(s):
When the DNA-binding site for the Saccharomyces cerevisiae transcription activator GAL4 is placed upstream of the Schizosaccharomyces pombe ADH1 TATA box, transcription of the ADH1 gene is activated in S. pombe in vivo by an endogenous transcription factor. In vitro studies show that this S. pombe protein, PGA4, binds specifically to DNA containing a GAL4 site and that when two GAL4 sites are present, this protein binds cooperatively. Cooperating binding of PGA4 to DNA is favored if the GAL4 sites are separated by an integral number of turns of the DNA helix.
1990 ◽
Vol 10
(4)
◽
pp. 1432-1438
◽
1993 ◽
Vol 13
(4)
◽
pp. 2091-2103
1992 ◽
Vol 12
(9)
◽
pp. 4215-4229
Keyword(s):
1991 ◽
Vol 11
(4)
◽
pp. 1935-1943
1993 ◽
Vol 13
(12)
◽
pp. 7469-7475
◽
Keyword(s):
2021 ◽