THU0613-HPR ADAPTATION AND VALIDATION OF THE MINI OSTEOARTHRITIS KNEE AND HIP QUALITY OF LIFE (MINI-OAKHQOL) QUESTIONNAIRE IN TURKISH POPULATION

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 548.1-548
Author(s):  
M. T. Duruöz ◽  
S. Acer Kasman ◽  
H. H. Gezer

Background:The 20-item Mini-OAKHQOL was derived from the 40-item OAKHQOL questionnaire which was developed to assess the quality of life in subjects with osteoarthritis of the lower limbs. It has 5 subscales containing physical activities, mental health, pain, social support, social functioning; and two independent items addressing sex life and professional life (1). The Mini-OAKHQOL’s good psychometric properties have recently been shown and validation studies have been done in several populations (1,2).Objectives:We aimed to investigate the validity and reliability of the Turkish version of the Mini-OAKHQOL in patients with knee and hip osteoarthritis.Methods:Patients diagnosed with knee or hip osteoarthritis clinically and radiologically were included in the study. Demographic data were noted. The French version of Mini-OAKHQOL was used for translation and adaptation. Translation-back translation methodology was applied and cross-cultural adaptation of the Mini-OAKHQOL into Turkish was done. Face and content validities were evaluated by cognitive information interviews with patients and expert committee. Internal consistency of the scale was made with Cronbach alpha coefficient. Convergent validity was evaluated by the correlations of Mini-OAKHQOL with Nothingam Health Profile (NHP), subscales of Short form 36 (SF-36), and VAS of the quality of life. The relations of the Mini-OAKHQOL with age, BMI, disease duration, VAS of the pain, WOMAC, and Lequesne Index were assessed for divergent validity. P <0.05 was considered significant.Results:Seventy-three patients (63 female, 10 male) with the mean age of 57.22 (SD: 9.91) years were recruited. The main site of the symptomatic lower limb osteoarthritis was knee in 44, hip in 25, and both in 4 patients. The mean BMI was 31.69 (SD: 11.06) and the median disease duration was 36 months (IQR: 12–72). Turkish version of Mini- OAKHQOL had a good face and content validity. Cronbach’s alpha coefficients of the subscales for internal consistency were 0.927, 0.841, 0.867, 0.771, and 0.677. Physical activities, mental health, pain dimensions of Mini-OAKHQOL had moderate to high correlations with Nottingham Health Profile and the physical functioning, physical role limitations, energy/fatigue, social functioning, pain, and general health subscales of SF-36 (rho between 0.484-0.748). The social function subscale of Mini-OAKHQOL had mild significant correlations with emotional well-being (rho: 0.239) and general health (rho: 0.315) subscales of SF36. The subscales of Mini-OAKHQOL had no correlation with disease duration, BMI, and age; and had generally moderate correlations with VAS-pain, Lequesne Index, and the WOMAC subscales. These data show good convergent and divergent validities of Mini-OAKHQOL.Conclusion:The Turkish version of the Mini-OAKHQOL is a valid and reliable instrument to assess the quality of life in patients with knee/hip osteoarthritis. In addition, it is a simple, accurate, disease-specific, and not time-consuming self-report instrument.References:[1]Guillemin F, Rat AC, Goetz C, Spitz E, Pouchot J, Coste J. The Mini-OAKHQOL for knee and hip osteoarthritis quality of life was obtained following recent shortening guidelines. J Clin Epidemiol. 2016;[2]Gonzalez Sáenz de Tejada M, Bilbao A, Herrera C, García L, Sarasqueta C, Escobar A. Validation of the Mini-OAKHQOL for use in patients with osteoarthritis in Spain. Clin Rheumatol. 2017;Disclosure of Interests:None declared

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Rainer Lüdtke ◽  
Stefan N. Willich ◽  
Thomas Ostermann

Background. Cohort studies have reported that patients improve considerably after individualised homeopathic treatment. However, these results may be biased by regression to the mean (RTM).Objective. To evaluate whether the observed changes in previous cohort studies are due to RTM and to estimate RTM adjusted effects.Methods. SF-36 quality-of-life (QoL) data from a German cohort of 2827 chronically diseased adults treated by a homeopath were reanalysed by Mee and Chua’s modifiedt-test.Results. RTM adjusted effects, standardized by the respective standard deviation at baseline, were 0.12 (95% CI: 0.06–0.19,P<0.001) in the mental and 0.25 (0.22–0.28,P<0.001) in the physical summary score. Small-to-moderate effects were confirmed for the most individual diagnoses in physical, but not in mental component scores. Under the assumption that the true population mean equals the mean of all actually diseased patients, RTM adjusted effects were confirmed for both scores in most diagnoses.Conclusions. Changes in QoL after treatment by a homeopath are small but cannot be explained by RTM alone. As all analyses made conservative assumptions, true RTM adjusted effects are probably larger than presented.


Stroke ◽  
2015 ◽  
Vol 46 (suppl_1) ◽  
Author(s):  
Suzanne H Lo ◽  
Anne M Chang ◽  
Janita P Chau ◽  
Glenn E Gardner

Introduction: Health-related quality of life is a significant outcome of stroke survivors’ recovery. The 49-item English version of the Stroke Specific Quality of Life Scale (SSQOL) (Williams et al., 2009) is a stroke-specific assessment of stroke survivors’ health-related quality of life in 12 domains. However there has been no Chinese version of the scale for Chinese stroke survivors in Hong Kong. Aim: To examine the reliability and validity of the Chinese version of Stroke Specific Quality of Life Scale (SSQOL-C) in stroke survivors. Methods: SSQOL was translated into Chinese and blind back-translated by independent bilingual baccalaureate nursing students. Content validity was reviewed by an expert panel which consisted of one nurse academic, one nurse manager, three advanced practice nurses, and two registered nurses. A cross-sectional study was conducted to validate the translated version. A convenience sample of 135 adult stroke survivors were recruited from three community centres and a stroke support group in Hong Kong. Internal consistency analysis was performed. Pearson’s correlation coefficients were calculated between SSQOL-C, SF-36, and Frenchay Activities Index (FAI) to determine the convergent validity. Results: Content validity index of SSQOL-C was 0.99. SSQOL-C had high internal consistency with Cronbach’s alpha of 0.94 for the total scale, and between 0.65 and 0.90 for the 12 domains. The total SSQOL-C scores showed significant positive correlations with SF-36 physical health (r=0.58, p<0.01) and mental health (r=0.54, p<0.01) component scores, and FAI score (r=0.59, p<0.01). SSQOL-C physical subtotal scores showed significant positive correlations with SF-36 physical health (r=0.55, p<0.01) and mental health (r=0.43, p<0.01) component scores, and FAI score (r=0.54, p<0.01). SSQOL-C psychosocial subtotal scores showed significant positive correlations with SF-36 physical health (r=0.52, p<0.01) and mental health (r=0.56, p<0.01) component scores, and FAI score (r=0.56, p<0.01). Conclusion: The results showed SSQOL-C had good content and convergent validity, and reliability in Chinese stroke survivors. Further evaluation of factor structure of SSQOL-C will be conducted to determine its validity.


2012 ◽  
Vol 16 (4) ◽  
pp. 301-308 ◽  
Author(s):  
Dinalva L. Cabral ◽  
Glória E. C. Laurentino ◽  
Caroline G. Damascena ◽  
Christina D. C. M. Faria ◽  
Priscilla G. Melo ◽  
...  

2020 ◽  
Author(s):  
ming zhang ◽  
Lin Fan ◽  
Meibian Zhang ◽  
Baofeng Liu ◽  
Qiang Zeng

Abstract Background p -Phenylenediamine (PPD) is a common component of hair dye, indicating the clinical characteristics of skin contact allergy and asthma with impaired pulmonary function. Howerver the adverse effects of PPD occupational exposure was rarely mentioned. The purpose of this study was to explore the PPD-induced pulmonary function, pruritus and health-related quality of life (HRQOL) of industrial workers of hair dye. Methods We recruited 124 workers from a hair dye manufacturer exposed to PPD. Individual PPD exposure and pulmonary function of workers were measured. The quality of life and subjective pruritus of workers was also assessed by SF-36 and VAS of pruritus, respectively. Results In the high PPD-exposed group, FVC% (percentage of forced vital capacity) was higher, while FEV1/FVC% (ratio percentage of forced expiratory volume) was lower than that in the low PPD-exposed group ( P <0.05). In terms of the HRQOL, the scores of mental health and vitality of the high PPD-exposed group were the lowest of all groups ( P <0.05), while the score of VAS was significantly higher than that of other two groups ( P <0.001). PPD levels were negatively correlated with vitality and mental health ( P <0.01). Higher PPD exposure level was correlated with a significantly higher VAS level (OR 9.394; 95%CI: 1.710, 51.622; P =0.010). The structural equation model provided a good fit to the data (χ2/df =1.607, GFI =0.901, AGFI =0.934, RMSEA =0.007, IFI =0.977, CFI =0.960, PGFI =0.615). And showed that PPD exposed level have positive effects on VAS level (β = 0.213, P <0.001). Then PPD exposed level partly via lack total score of SF-36 (β = -0.465, P =0.002); on negative effects on VAR level (β = -0.110, P <0.001). Conclusion Occupational PPD exposure might be associated with pulmonary function impairment, poor HRQOL, and subjective pruritus of workers.


2020 ◽  
Vol 102-B (7) ◽  
pp. 845-851 ◽  
Author(s):  
Graham S. Goh ◽  
Ming Han Lincoln Liow ◽  
You Wei Adriel Tay ◽  
Jerry Yongqiang Chen ◽  
Sheng Xu ◽  
...  

Aims While patients with psychological distress have poorer short-term outcomes after total knee arthroplasty (TKA), their longer-term function is unknown. We aimed to 1) assess the influence of preoperative mental health status on long-term functional outcomes, quality of life, and patient satisfaction; and 2) analyze the change in mental health after TKA, in a cohort of patients with no history of mental health disorder, with a minimum of ten years’ follow-up. Methods Prospectively collected data of 122 patients undergoing primary unilateral TKA in 2006 were reviewed. Patients were assessed pre- and postoperatively at two and ten years using the Knee Society Knee Score (KSKS) and Function Score (KSFS); Oxford Knee Score (OKS); and the Mental (MCS) and Physical Component Summary (PCS) which were derived from the 36-Item Short-Form Health Survey questionnaire (SF-36). Patients were stratified into those with psychological distress (MCS < 50, n = 51) and those without (MCS ≥ 50, n = 71). Multiple regression was used to control for age, sex, BMI, Charlson Comorbidity Index (CCI), and baseline scores. The rate of expectation fulfilment and satisfaction was compared between patients with low and high MCS. Results There was no difference in the mean KSKS, KSFS, OKS, and SF-36 PCS at two years or ten years after TKA. Equal proportions of patients in each group attained the minimal clinically important difference for each score. Psychologically distressed patients had a comparable rate of satisfaction (91.8% (47/51) vs 97.1% (69/71); p = 0.193) and fulfilment of expectations (89.8% vs 97.1%; p = 0.094). The proportion of distressed patients declined from 41.8% preoperatively to 29.8% at final follow-up (p = 0.021), and their mean SF-36 MCS improved by 10.4 points (p < 0.001). Conclusion Patients with poor mental health undergoing TKA may experience long-term improvements in function and quality of life that are comparable to those experienced by their non-distressed counterparts. These patients also achieved a similar rate of satisfaction and expectation fulfilment. Undergoing TKA was associated with improvements in mental health in distressed patients, although this effect may be due to residual confounding. Cite this article: Bone Joint J 2020;102-B(7):845–851.


2010 ◽  
Vol 37 (10) ◽  
pp. 2081-2085 ◽  
Author(s):  
MIKKEL FAURSCHOU ◽  
LENE SIGAARD ◽  
JAKOB BUE BJORNER ◽  
BO BASLUND

Objective.To investigate whether patients with Wegener’s granulomatosis (WG) experience reduced health-related quality of life (HRQOL) after accomplishment of remission, and to study the influence of WG-associated organ damage on HRQOL.Methods.Sixty-eight patients with inactive WG and 680 randomly selected, age- and sex-matched controls of the Danish background population completed the Medical Outcomes Study Short-Form 36 (SF-36) survey for evaluation of HRQOL. Irreversible organ damage attributable to WG and/or its treatment was assessed using the Vasculitis Damage Index (VDI).Results.The median disease duration was 7.5 (range 1–26) years in the WG group, and the median total VDI score was 2.0 (range 0–7). Compared to controls, WG patients reported impaired HRQOL reflected by significantly lower SF-36 physical component summary scores (PCS) and mental component summary scores (MCS) (p < 0.001) and by significantly lower scores in 7 out of 8 SF-36 subscales (p ≤ 0.001). In the WG group, no statistically significant correlations were found between the different SF-36 scores and the total VDI score, number of organ systems affected by damage, disease duration, or number of WG relapses. Patients with organ failure or other major forms of damage did not report significantly lower HRQOL than less severely affected patients.Conclusion.WG patients experience significantly reduced HRQOL even in phases with no apparent vasculitis disease activity. Our data indicate that the level of HRQOL does not correlate well with the extent of vasculitis-associated organ damage in WG.


2009 ◽  
Vol 35 (5) ◽  
pp. 436-441 ◽  
Author(s):  
Maria Penha Uchoa Sales ◽  
Maria Irenilza Oliveira ◽  
Isabela Melo Mattos ◽  
Cyntia Maria Sampaio Viana ◽  
Eanes Delgado Barros Pereira

OBJECTIVE: To evaluate changes in health-related quality of life (HRQoL) after twelve months of smoking cessation. METHODS: This was a prospective study to evaluate the effectiveness of a smoking cessation program on the quality of life of 60 self-referred subjects, at a public hospital, during the period of August 2006 to December 2007. The program consisted of 2-h group sessions once a week during the first month and then every 15 days over six months, followed by monthly phone contacts for another six months. The treatment was based on behavior modification and the use of bupropion in combination with nicotinic replacement therapy. Abstinence was verified by exhaled CO measurements. Patient HRQoL was quantified using the Medical Outcomes Study 36-item Short-Form Health Survey (SF-36) questionnaire. Differences in quality of life scores between quitters and non-quitters at twelve months after the initial intervention were evaluated using analysis of covariance with baseline characteristics as covariates. RESULTS: Self-reported quality of life scores were significantly higher among the 40 quitters than among the 20 non-quitters. The following SF-36 domains were most affected: role-emotional (p = 0.008); general health (p = 0.006); vitality (p < 0.001); and mental health (p = 0.002). At twelve months after the smoking cessation intervention, the SF-36 mental component and physical component summary scores were higher among quitters than among non-quitters (p = 0.004 and p = 0.001, respectively). CONCLUSIONS: Our findings illustrate that smoking abstinence is related to better HRQoL, especially in aspects of mental health.


2015 ◽  
Vol 16 (6) ◽  
pp. 621-625 ◽  
Author(s):  
Anja Kutscher ◽  
Ulf Nestler ◽  
Matthias K. Bernhard ◽  
Andreas Merkenschlager ◽  
Ulrich Thome ◽  
...  

OBJECT Congenital hydrocephalus has a major impact on the lives of patients and their relatives, as well as their long-term neurological development and social integration. The aim of this study was to assess the self-reported health-related quality of life (HRQOL) of patients after reaching adulthood. METHODS A total of 31 patients who required CSF shunt treatment for congenital hydrocephalus within the 1st year of life (between 1963 and 1987) agreed to undergo a structured SF-36 self-assessment. An age-matched German standard cohort was used as control. Additional parameters of surgical, social, and global neurological outcome were analyzed. The mean patient age was 35 years (range 26–51 years, 13 females and 18 males). Hydrocephalus etiologies were posthemorrhagic hydrocephalus (n = 9), postinfectious hydrocephalus (n = 5), aqueductal stenosis (n = 10), myelomeningocele (n = 2), and unknown cause (n = 5). RESULTS The mean modified Rankin Scale score was 1.6 (range 0–4). Hydrocephalic patients achieved lower scores for the SF-36 items physical functioning (70.5 vs 93.5, p < 0.05), physical role functioning (74.2 vs 88.3, p < 0.05), and general health perceptions (64.5 vs 72.3, p < 0.05). Emotional, social role functioning, and mental health items did not differ between the groups. Assessment of vitality and pain resulted in a trend to worse values. Whereas the Physical Component Summary score was lower (46.1 vs 54.3, p < 0.05), the Mental Component Summary score was not significantly different (50.2 vs 48.7, p = 0.3). There was neither a statistically significant difference between subgroups of different etiologies nor an association with the number of subsequent hydrocephalus-related surgeries. CONCLUSIONS Adult HRQOL for patients with congenital hydrocephalus appears to be similar to that for healthy con with regard to mental health and social functioning aspects. Physical impairment is a predominant factor of compro quality of life.


2013 ◽  
Vol 39 (3) ◽  
pp. 349-356 ◽  
Author(s):  
Juliessa Florian ◽  
Adalberto Rubin ◽  
Rita Mattiello ◽  
Fabricio Farias da Fontoura ◽  
Jose de Jesus Peixoto Camargo ◽  
...  

OBJECTIVE: To investigate the impact of a pulmonary rehabilitation program on the functional capacity and on the quality of life of patients on waiting lists for lung transplantation. METHODS: Patients on lung transplant waiting lists were referred to a pulmonary rehabilitation program consisting of 36 sessions. Before and after the program, participating patients were evaluated with the six-minute walk test and the Medical Outcomes Study 36-item Short-Form Health Survey (SF-36). The pulmonary rehabilitation program involved muscle strengthening exercises, aerobic training, clinical evaluation, psychiatric evaluation, nutritional counseling, social assistance, and educational lectures. RESULTS: Of the 112 patients initially referred to the program, 58 completed it. The mean age of the participants was 46 ± 14 years, and females accounted for 52%. Of those 58 patients, 37 (47%) had pulmonary fibrosis, 13 (22%) had pulmonary emphysema, and 18 (31%) had other types of advanced lung disease. The six-minute walk distance was significantly greater after the program than before (439 ± 114 m vs. 367 ± 136 m, p = 0.001), the mean increase being 72 m. There were significant point increases in the scores on the following SF-36 domains: physical functioning, up 22 (p = 0.001), role-physical, up 10 (p = 0.045); vitality, up 10 (p < 0.001); social functioning, up 15 (p = 0.001); and mental health, up 8 (p = 0.001). CONCLUSIONS: Pulmonary rehabilitation had a positive impact on exercise capacity and quality of life in patients on lung transplant waiting lists.


2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Ahmad Naqib bin Baharom ◽  
Sulis Bayu Sentono

Abstract. Background: Osteoarthritis is a degenerative process disease and is a leading cause of pain and disability. It is also ranked as 11th highest contributor to disability worldwide. Many risk factors have been known that can speed the progression of osteoarthritis.Purpose: To study the correlation between age, gender, BMI, physical activities and history of trauma with quality of life in clinically diagnosed osteoarthritis patients in Orthopaedic and Traumatology Outpatient Clinic between January 2015 until December 2016.Method: This research is a hospital-based cross-sectional analytic study. The samples are clinically diagnosed osteoarthritis patients in Orthopaedic and Traumatology Outpatient Clinic in RSUD Dr. Soetomobetween January 2015 until December 2016.Results: There were 43 patients that can be reach in Orthopaedic and Traumatology Outpatient Clinic in RSUD Dr. Soetomo between January 2015 until December 2016. The mean age is 54.35 ± 5.32 years old and the most gender in the subjects are female (72.1%). The mean BMI of the subjects are 26.20 ± 3.75 and most of them are overweight (60.5%). Most of the subjects never have history of trauma (76.7%) and also have an inactive physical activities (65.1%). The quality of life of the research subjects have a mean score of 42.86 ± 12.54. After that, the correlation between the age, gender, BMI, physical activities, history of trauma and quality of life is tested. It is found that there is a significant correlation between gender, BMI and physical activities with quality of life but no significant correlation between age and history of trauma with quality of life.Conclusion: Gender still a main role in osteoarthritis development with women have a higher risk. Also patients with higher BMI and inactive patients will have a decrease quality of life. Most of the patients have an moderate quality of life.Keywords: osteoarthritis, quality of life, age, gender, physical activities, BMI, history of trauma


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