scholarly journals THU0509 IMPACT OF PEDIATRIC RHEUMATIC DISEASES ON MEXICAN CAREGIVERS.

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 493.2-493
Author(s):  
B. Fortuna ◽  
I. Peláez-Ballestas ◽  
F. García-Rodríguez ◽  
E. Faugier ◽  
S. Mendieta ◽  
...  

Background:Pediatric rheumatic diseases (PRD) have an important impact on different aspects of the patients’ and caregivers’ life, such as physical, emotional, economic, and social. Some studies have shown that parents of patients with PRD have important impact but there is a lack of information of this topic from Latinamerican countries.Objectives:The aim of this study is to describe and analyze the impact of juvenile idiopathic arthritis (JIA), juvenile systemic lupus erythematosus (JSLE), and juvenile dermatomyositis (JDM) on Mexican primary caregivers.Methods:This is a multicenter cross-sectional study conducted in third-level reference pediatric hospitals in Mexico from December 2018 to November 2019. We included primary caregivers of pediatric patients with JIA, JSLE, and JDM that were treated in participant centers.CAREGIVERS questionnaire, a validated multiassesment tool to measure the impact of PRD on caregivers, was applied to the participants. Collection of social, demographic, and clinical data was also performed and correlated with questionnaire results.Results:A total of 200 primary caregivers participates in the study (109 JIA, 28 JDM, and 63 JSLE), aged 38 (IQR 32 – 46), mostly women (84.5%), from 6 centers, representing 13/32 Mexican states (Figure). One third (78) had a remunerated job, 123 (61.5%) had a relationship, 77 (38.5%) reached high school or higher, and 131 (65.5%) spends more than one hour to get to the center. Patients cared aged 12 (IQR 9 – 16), mostly women (67%), 87 (43.5%) with active disease, 43 (21.5%) with any disability, 94% and 29% treated with DMARD and biologics, respectively.Feelings of worry and sadness predominant at diagnosis that decreased over time (42.5% and 28.5% vs 9.5% and 31.5%, respectively) and changed for peace (44%). Concerns about disabilities were more frequent on JIA group (34%), while pain and economic issues in JSLE (47% and 30%, respectively. Most of the caregivers feel anxiety about the future of their patients (148, 74%), regardless of the diagnosis. Participants reported that the way they spend the time, social life, and personal health worsened since diagnosis (49.5%, 32%, and 34.5%, respectively), especially in those with JSLE (60%, 39%, 46%). In 126 (63%) participants the economic situation worsened, 129 (64.5%) borrowed money (76% in JSLE, P = .03), 63 (31.5%) had problems to buy medications, and 48.5% have had problems at work. In 25 (12.5%), the family relationship was affected after diagnosis, however, the main supportive network reported were family members.Conclusion:This work described the main impacted areas in life of primary caregivers of patients with PRD, showing a perspective of the burden of the disease.References:[1]Cohen EM. Pediatr Rheumatol [Internet]. Pediatric Rheumatology; 2017;15(1):6.[2]Torres-Made.Pediatr Rheumatol18,3 (2020).Disclosure of Interests:None declared

PLoS ONE ◽  
2022 ◽  
Vol 17 (1) ◽  
pp. e0262325
Author(s):  
Nazish Imran ◽  
Fauzia Naz ◽  
Muhammad Imran Sharif ◽  
Sumbul Liaqat ◽  
Musarrat Riaz ◽  
...  

Background COVID-19 has posed unique challenges for adolescents in different dimensions of their life including education, home and social life, mental and physical health. Whether the impact is positive or negative, its significance on the overall shaping of adolescents’ lives cannot be overlooked. The aim of the present study was to explore impacts of the pandemic on the adolescents’ everyday lives in Pakistan. Methods Following ethical approval, this cross-sectional study was conducted through September to December, 2020 via an online survey on 842 adolescents with the mean age of 17.14 ± SD 1.48. Socio-demographic data and Epidemic Pandemic Impact Inventory-Adolescent Adaptation (EPII-A) was used to assess the multi-dimensional effects of the pandemic. Results Among the 842 participants, 84% were girls. Education emerged as the most negatively affected Pandemic domain (41.6–64.3%). Most of the adolescents (62.0–65.8%) had reported changes in responsibilities at home including increased time spent in helping family members. Besides, increase in workload of participants and their parents was prominent (41.8% & 47.6%). Social activities were mostly halted for approximately half (41–51%) of the participants. Increased screen time, decreased physical activity and sedentary lifestyle were reported by 52.7%, 46.3% and 40.7% respectively. 22.2–62.4% of the adolescents had a direct experience with quarantine, while 15.7% experienced death of a close friend or relative. Positive changes in their lives were endorsed by 30.5–62.4% respondents. Being male and older adolescents had significant association with negative impact across most domains (p<0.05). Conclusions Results have shown that COVID-19 exert significant multidimensional impacts on the physical, psycho-social, and home related domains of adolescents that are certainly more than what the previous researches has suggested.


2021 ◽  
Author(s):  
Kengo Yokomitsu ◽  
Kazuya Inoue ◽  
Tomonari Irie

Abstract BackgroundPachinko and pachislot are popular types of gambling activities in Japan. Prior studies in Japan have reported a concerning prevalence of problem gambling among adult players. While these studies have identified various gambling-related harms, Japanese research on harm-minimization strategies is scarce. Therefore, the present study aimed to analyze the effectiveness of low-investment pachinko and pachislot as a harm-reduction strategy. MethodsWe considered gamblers who played games that cost the typical amount of money to be “normal-pachi players.” Those who played low-investment games were categorized as “half-pachi players” and “quarter-pachi players,” reflecting those who played games at half or one quarter the cost of a typical machine, respectively. To assess the harm-reduction effect, a one-way ANCOVA was conducted to compare the impact of the groups (normal-pachi players [n= 101], half-pachi players [n= 104], and quarter-pachi players [n= 100]) on dependent variables, namely the number of days players had gambled during the prior month; total time and amount of money spent on gambling; debts caused by gambling; gambling severity; cognitive distortion; depressive symptoms; and problems in work, family, and social life. ResultsWe demonstrated that the amount of money spent by quarter-pachi players on gambling during the past month was lower than that of normal-pachi players. However, we did not find significant differences with respect to any other gambling-related harms among normal-, half-, and quarter-pachi players. ConclusionLow-investment pachinko and pachislot can reduce the amount of money spent on gambling. It can thus partly act as a harm-minimization strategy. Moreover, the results of the present study indicate that the problems at work affect various outcomes for gamblers. Given that 90% of the participants in this study were employed, the results of this study may have important implications for employed gamblers.


2012 ◽  
Vol 39 (10) ◽  
pp. 1934-1941 ◽  
Author(s):  
JASMINE R. GADDY ◽  
EVAN S. VISTA ◽  
JULIE M. ROBERTSON ◽  
AMY B. DEDEKE ◽  
VIRGINIA C. ROBERTS ◽  
...  

Objective.Rheumatic diseases cause significant morbidity within American Indian populations. Clinical disease presentations, as well as historically associated autoantibodies, are not always useful in making a rapid diagnosis or assessing prognosis. The purpose of our study was to identify autoantibody associations among Oklahoma tribal populations with rheumatic disease.Methods.Oklahoma tribal members (110 patients with rheumatic disease and 110 controls) were enrolled at tribal-based clinics. Patients with rheumatic disease (suspected or confirmed diagnosis) were assessed by a rheumatologist for clinical features, disease criteria, and activity measures. Blood samples were collected and tested for common rheumatic disease autoantibodies [antinuclear antibody (ANA), anti-cyclic citrullinated peptide antibodies (anti-CCP), rheumatoid factor (RF), anti-Ro, anti-La, anti-Sm, anti-nRNP, anti-ribosomal P, anti-dsDNA, and anticardiolipins].Results.In patients with suspected systemic rheumatic diseases, 72% satisfied American College of Rheumatology classification criteria: 40 (36%) had rheumatoid arthritis (RA), 16 (15%) systemic lupus erythematosus, 8 (7%) scleroderma, 8 (7%) osteoarthritis, 4 (4%) fibromyalgia, 2 (2%) seronegative spondyloarthropathy, 1 Sjögren’s syndrome, and 1 sarcoidosis. Compared to controls, RA patient sera were more likely to contain anti-CCP (55% vs 2%; p < 0.001) or RF IgM antibodies (57% vs 10%; p < 0.001); however, the difference was greater for anti-CCP. Anti-CCP positivity conferred higher disease activity scores (DAS28 5.6 vs 4.45; p = 0.021) while RF positivity did not (DAS28 5.36 vs 4.64; p = 0.15). Anticardiolipin antibodies (25% of rheumatic disease patients vs 10% of controls; p = 0.0022) and ANA (63% vs 21%; p < 0.0001) were more common in rheumatic disease patients.Conclusion.Anti-CCP may serve as a more specific RA biomarker in American Indian patients, while the clinical significance of increased frequency of anticardiolipin antibodies needs further evaluation.


Psych ◽  
2020 ◽  
Vol 2 (4) ◽  
pp. 370-384
Author(s):  
Tim Jonas Lacker ◽  
Andreas Walther ◽  
Patricia Waldvogel ◽  
Ulrike Ehlert

Background: Relationship satisfaction has been identified as an important factor in terms of extradyadic sexual involvement. However, in men, fatherhood might be associated with infidelity by leading to changes in relationship satisfaction and the social life of parents. To date, no study has focused on the association of fatherhood and infidelity, nor the influence of fatherhood on the association between relationship satisfaction and infidelity. Methods: Using a cross-sectional design, 137 fathers and 116 non-fathers were assessed regarding relationship satisfaction, infidelity, and potential confounds. Results: Significantly more fathers reported having been unfaithful in the current relationship than non-fathers (30.7% vs. 17.2%). Fathers also reported longer relationship duration, higher relationship satisfaction, and lower neuroticism than non-fathers. Furthermore, fatherhood moderated the association between relationship satisfaction and infidelity insofar that only in non-fathers reduced relationship satisfaction was associated with infidelity. Conclusions: The results suggest that fatherhood increases the risk of engaging in extradyadic sexual activities and moderates the link between relationship satisfaction and infidelity. However, results need to be interpreted with caution due to the cross-sectional study design and the lack of information about the specific time point of the infidelity incident(s).


Geriatrics ◽  
2020 ◽  
Vol 5 (4) ◽  
pp. 96
Author(s):  
Bruno Corrado ◽  
Benedetto Giardulli ◽  
Francesco Polito ◽  
Salvatore Aprea ◽  
Mariangela Lanzano ◽  
...  

Urinary incontinence is a hygienic and psychosocial problem that often brings people to restrict their social life and to experience depression. The main aim of this study was to evaluate the impact of urinary incontinence on quality of life among residents of the Metropolitan City of Naples, Italy, using a newly designed multidimensional questionnaire. The secondary objective was to find which variables affect the quality of life and symptom severity in these patients. To do so, a sample composed of twenty-eight patients was recruited in a multicentre cross-sectional study. Most of the participants had a mild impairment (60%) concerning social life and self-perception, especially those whose education was above the primary level (p = 0.036) and those who followed a pelvic floor rehabilitation program (p = 0.002). Overflow urinary incontinence was associated with a greater deterioration in the aspirational and occupational domain (p = 0.044). Symptom severity was worse in those who had comorbidities (p = 0.038), who had a high body mass index (p = 0.008) or who used diuretics (p = 0.007). In conclusion, our results suggest that there is a significant impairment of quality of life in patients who have only primary education and who follow a pelvic floor rehabilitation program.


2015 ◽  
Vol 9 (1) ◽  
pp. 42-50 ◽  
Author(s):  
Ceres Eloah Lucena Ferretti ◽  
Ricardo Nitrini ◽  
Sonia Maria Dozzi Brucki

Costs with dementia have been the focus of research around the world and indirect costs to the caregiver appear in the literature as responsible for the greatest impact. In Latin American (LA) studies, indirect costs with dementia range from 60% to 75% of family income. OBJECTIVE: To present preliminary results of the study "Description of the methods and cost analysis with dementia" currently being conducted at the Behavioral and Cognitive Neurology Unit of Hospital de Clínicas of University of São Paulo - HC-FMUSP. METHODS: A cross-sectional study which, to date, includes interviews of 93 primary caregivers. The research protocol includes a sociodemographic questionnaire, the Functional Assessment Staging (FAST) scale, the Burden Interview (Zarit), an economic classification scale, and the Resource Utilization in Dementia (RUD) scale. RESULTS: Monthly indirect costs were US$ 1,122.40, US$ 1,508.90 and US$ 1,644.70 stratified into mild, moderate and severe dementia, respectively. The projected annual indirect costs were US$ 13,468.80, US$ 18,106.80 and US$ 19,736.40, representing 69 to 169% of family income. CONCLUSION: This small sample showed that the impact of indirect costs with dementia in Brazil may be higher than that reported in other Latin American (LA) studies. These initial results may represent an important contribution for further research on costs with dementia in LA.


2017 ◽  
Vol 44 (4) ◽  
pp. 512-518 ◽  
Author(s):  
Mariana Galante Santiago ◽  
Andréa Marques ◽  
Marianne Kool ◽  
Rinie Geenen ◽  
José António P. da Silva

Objective.The term “invalidation” refers to the patients’ perception that their medical condition is not recognized by the social environment. Invalidation can be a major issue in patients’ lives, adding a significant burden to symptoms and limitations while increasing the risk of physical and psychological disability. In this study in patients with rheumatic diseases, we investigated the relationship between invalidation and sociodemographic, clinical, psychological, and personality characteristics.Methods.This international cross-sectional study included 562 adults with rheumatoid arthritis (n = 124), spondyloarthritis (n = 85), systemic lupus erythematosus (n = 112), or fibromyalgia (FM; n = 241). Assessed were the family and health professionals subscales of the Illness Invalidation Inventory (3*I), happiness (Subjective Happiness Scale), personality (Ten-Item Personality Inventory), pain, and loneliness (numerical rating scales). Univariate and multivariate analyses were used to test different models.Results.Invalidation occurred in all rheumatic diseases, but patients with FM reported the most invalidation. Including all correlated variables in the multivariate model, pain remained as a determinant of invalidation by health professionals, but not by family. Regarding psychological variables, loneliness remained as a determinant of invalidation by family, but not by health professionals. FM and low levels of happiness, agreeableness, and conscientiousness were associated with invalidation while taking account of other variables.Conclusion.Invalidation occurs in all rheumatic diseases and patients with FM experience the most invalidation. Psychological factors (happiness, agreeableness, and conscientiousness), loneliness, and pain intensity are associated with invalidation, irrespective of the rheumatic disease and may deserve dedicated interventions.


2020 ◽  
Vol 66 (8) ◽  
pp. 1093-1099
Author(s):  
Wellington Douglas Rocha Rodrigues ◽  
Roseli Oselka Saccardo Sarni ◽  
Thais Tobaruela Ortiz Abad ◽  
Simone Guerra Lopes da Silva ◽  
Fabiola Isabel Suano de Souza ◽  
...  

SUMMARY AIM To describe the prevalence of dyslipidemia in children and adolescents with autoimmune rheumatic diseases (ARDs), particularly juvenile idiopathic arthritis (JIA), juvenile systemic lupus erythematosus (jSLE), and juvenile dermatomyositis (JDM). METHODS Retrospective cross-sectional study conducted in the pediatric rheumatology outpatient clinic. We evaluated 186 children and adolescents between the ages of 5 and 19 years. The medical records were reviewed for the following data: demographic and clinical features, disease activity, and lipid profile (triglycerides (TG), total cholesterol (TC), low density lipoprotein (LDL-C), high density lipoprotein (HDL-C) and very low density lipoprotein (VLDL-C)). In addition, non-HDL cholesterol was calculated as TC minus HDL-C. The cut-off points proposed by the American Academy of Pediatrics were used to classify the lipid profile. RESULTS Dyslipidemia was observed in 128 patients (68.8%), the most common being decreased HDL-C (74 patients, 39.8%). In the JIA group there was an association between the systemic subtype and altered LDL-C and NHDL-C, which demonstrated a more atherogenic profile in this subtype (p=0.027 and p=0.017, respectively). Among patients with jSLE, the cumulative corticosteroid dose was associated with an increase in LDL-C (p=0.013) and with a decrease in HDL-C (p=0.022). CONCLUSION Dyslipidemia is common in children and adolescents with ARDs, especially JIA, jSLE, and JDM, and the main alteration in the lipid profile of these patients was decreased HDL-C.


2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 909.1-909
Author(s):  
M. Viola ◽  
A. Benitez ◽  
C. Garbarino ◽  
G. Rodriguez ◽  
F. Benavidez ◽  
...  

Background:Infectious diseases are increased in patients with rheumatic disorders; vaccination improves morbidity and mortalityObjectives:The aim of this study was to describe the frequency of vaccination in patients with rheumatic disorders and to compare the results with those obtained in 2009 and 2013 in a similar population. We also identified factors leading to lack of vaccination and patients beliefs on vaccines.Methods:Multicentric cross sectional study in patients with autoinmune diseases from external rheumatology offices. Evaluation of vaccination status and patients´ knowledge about vaccines were studied. A comparative analysis was carried out with the series registered in 2009 and 2013 in a similar population.Results:179 patients (158 female, 88.3% and 21 male, 11.7%) were evaluated. Median age was 52 years. Main pathologies were: Rheumatoid Arthritis 65.9% (n:118), Systemic Lupus Erythematosus 11.7% (n:21), Systemic Sclerosis 3.9% (7), Sjogren Syndrome n = 3.4% (n:6), other diseases 15% (n: 27). Median disease duration: 8.87 years. Ninety three percent of patients (n:167) were taking inmunomodulators and 36.8% (n: 66) were using oral corticosteroids (20mg/day or less); 26,8% patients (n: 48) were receiving biological therapies. Vaccination frequency in the population was: Influenza 82% (147); 13-valent conjugate pneumococcal 69.3% (124), 23-valent pneumococcal 64.2% (115) and hepatitis B 62% (111). Comparative with 2009 and 2013 series there was an increase in the rate of vaccinated patients: influenza (82% vs. 39,1% and 74,2% respectively), antineumococcal (64% vs. 17% and 29%) and hepatitis B (62% vs. 6,7% and 26,7%).Reasons for non-vaccination were absence of medical indication (41% of patients for hepatitis B; 32% for 23-valent pneumococcal; 38% for 13-valent pneumococcal and 34% for influenza).139 patients (77, 7%) knew the benefits of vaccines, 164 (91, 6%) thought vaccines are useful; 134 (74,9%) reported that vaccines may decrease dying probability, 155 (86,5%) thought that vaccines are effective to prevent diseases and 149 patients (83,2%) believed that they prevent serious infections. 71 patients (39%) believed that vaccines can lead to serious consequences and 99 (55,3%) that they are more likely to acquire infections than the rest of the population.Conclusion:Frequency of vaccination has increased since 2009 but there is still misinformation regarding vaccines risks and benefits. Promotion and information is essential to improve adherence.References:[1]2019 update of EULAR recommendations for vaccination in adult patients with autoimmune inflammatory rheumatic diseases. Furer V, et al. Ann Rheum Dis 2020;79:39–52[2] Vaccines and Disease-Modifying Antirheumatic Drugs: Practical Implications for the Rheumatologist. Friedman MA et al. Rheum Dis Clin North Am. 2017 Feb; 43 (1):1-13.[3] Recommendations and barriers to vaccination in systemic lupus erythematosus. Garg M et al. Autoimmun Rev. 2018 Oct; 17 (10):990-1001.[4] Comparison of national clinical practice guidelines and recommendations on vaccination of adult patients with autoimmune rheumatic diseases. Papadopoulou D. et al. Rheumatol Int. 2014 Feb;34 (2):151-63.[5] Guías de recomendaciones de prevención de infecciones en pacientes que reciben modificadores de la respuesta biológica. Jordán R. Et al. Rev Arg Reumatol. 2014; 25 (2): 08-26.Disclosure of Interests:Malena Viola: None declared, Alejandro Benitez: None declared, Cecilia Garbarino: None declared, Gonzalo Rodriguez: None declared, Federico Benavidez: None declared, Claudia Peon: None declared, Eliana Soledad Blanco: None declared, Hernan Molina: None declared, Gimena Gómez: None declared, griselda redondo: None declared, Maria DeLaVega: None declared, Dario Mata: None declared, Augusto Riopedre: None declared, Osvaldo Messina Speakers bureau: Amgen; Americas Health Foundation; Pfizer


VASA ◽  
2019 ◽  
Vol 48 (3) ◽  
pp. 262-269 ◽  
Author(s):  
Christian-Alexander Behrendt ◽  
Tilo Kölbel ◽  
Thea Schwaneberg ◽  
Holger Diener ◽  
Ralf Hohnhold ◽  
...  

Abstract. Background: Worldwide prevalence of peripheral artery disease (PAD) is increasing and peripheral vascular intervention (PVI) has become the primary invasive treatment. There is evidence that multidisciplinary team decision-making (MTD) has an impact on in-hospital outcomes. This study aims to depict practice patterns and time changes regarding MTD of different medical specialties. Methods: This is a retrospective cross-sectional study design. 20,748 invasive, percutaneous PVI of PAD conducted in the metropolitan area of Hamburg (Germany) were consecutively collected between January 2004 and December 2014. Results: MTD prior to PVI was associated with lower odds of early unsuccessful termination of the procedures (Odds Ratio 0.662, p < 0.001). The proportion of MTD decreased over the study period (30.9 % until 2009 vs. 16.6 % from 2010, p < 0.001) while rates of critical limb-threatening ischemia (34.5 % vs. 42.1 %), patients´ age (70 vs. 72 years), PVI below-the-knee (BTK) (13.2 % vs. 22.4 %), and rates of severe TASC C/D lesions BTK (43.2 % vs. 54.2 %) increased (all p < 0.001). Utilization of MTD was different between medical specialties with lowest frequency in procedures performed by internists when compared to other medical specialties (7.1 % vs. 25.7 %, p < 0.001). Conclusions: MTD prior to PVI is associated with technical success of the procedure. Nonetheless, rates of MTD prior to PVI are decreasing during the study period. Future studies should address the impact of multidisciplinary vascular teams on long-term outcomes.


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