scholarly journals Exceptionally large, atypically located spindle cell lipoma

2019 ◽  
Vol 12 (10) ◽  
pp. e232209
Author(s):  
Mitchell John ◽  
Shaan Patel ◽  
George Joseph
Keyword(s):  
Spindle Cell ◽  
Excisional Biopsy ◽  
Large Mass ◽  
Spindle Cell Lipoma ◽  
Rare Presentation ◽  
Spindle Cells ◽  
Histological Appearance ◽  
Bony Involvement ◽  
Immunohistological Analysis ◽  
Rule Out

Spindle cell lipomas are a rare subtype of lipoma typically occurring in the shawl region of middle-aged men with a characteristic histological appearance consisting of mature adipocytes, ropey collagen and spindle cells. Those of extraordinary size or atypical anatomic location require a proper immunohistological workup to rule out more ominous malignancy. The authors report the rare presentation of a 54-year-old man with a large mass of the left palm causing discomfort and paresthesia for 6 months. Radiographs showed a radiolucent mass without mineralisation or bony involvement. MRI demonstrated a non-contrast-enhancing homogeneous lipomatous mass encompassing flexor tendons of the palm. Elective excisional biopsy and immunohistological analysis were consistent with spindle cell lipoma measuring 11 cm × 7 cm × 4 cm. This case is the largest spindle cell lipoma of the hand reported in the literature and appears to be the largest described in the upper extremity.

scholarly journals Left Supraclavicular Spindle Cell Lipoma

2010 ◽  
Vol 2010 ◽  
pp. 1-4 ◽  
Author(s):  
Oladejo Olaleye ◽  
Bertram Fu ◽  
Ram Moorthy ◽  
Charles Lawson ◽  
Myles Black ◽  
...  
Keyword(s):  
Spindle Cell ◽  
Excisional Biopsy ◽  
Neurological Deficits ◽  
Excision Biopsy ◽  
Low Grade ◽  
Spindle Cell Lipoma ◽  
Rare Presentation ◽  
Spindle Cells ◽  
Immuno Histochemistry ◽  
Rare Benign Tumour

Background. Spindle cell lipoma (SCL) is a benign lipomatous tumour, typically occurring in the posterior neck, shoulder or upper back of elderly males. They compose of fat, CD34 positive spindle cells, and ropey collagen on a myxoid matrix. This case highlights a rare presentation of SCL and the need for pre-operative diagnosis.Case Report. A 63-year-old gentleman presented with a pre-existing left supraclavicular mass that had recently increased in size. FNA and CT Scans were performed and results discussed in the mutidisciplinary team meeting. Excisional biopsy was recommended.Radiology. CT neck showed a left supraclavicular mass of fatty density with fine internal septations. A low-grade liposarcoma could not be excluded.Histopathology. FNA was indeterminate. Histology of specimen showed bland spindle cells with no evidence of malignancy. Immuno-histochemistry showed SCL with CD34 positivity and negative staining on CDK4 and p16.Management. Excision biopsy of the mass was performed which was technically difficult as the mass invaginated around the brachial plexus. The patient recovered well post-operatively with no neurological deficits.Conclusion. Spindle cell lipoma is a rare benign tumour and a pre-operative diagnosis based on the clinical context, imaging and immuno-histochemistry is crucial to management.

scholarly journals Lipoma of the Thumb: Spindle Cell Subtype

2016 ◽  
Vol 2016 ◽  
pp. 1-3 ◽  
Author(s):  
Johnny El Rayes ◽  
Roula Bou Sader ◽  
Elie Saliba
Keyword(s):  
Differential Diagnosis ◽  
Soft Tissue ◽  
Clinical Examination ◽  
Spindle Cell ◽  
Excisional Biopsy ◽  
Spindle Cell Lipoma ◽  
Cell Subtype ◽  
Soft Tissue Swelling ◽  
Palmar Aspect

We report hereby the case of a 61-year-old man who presented with a soft-tissue swelling on the palmar aspect of the thumb. A detailed clinical examination followed by ultrasonography and excisional biopsy confirmed a spindle cell lipoma. Lipomas are rare in the hand and exceptional in the fingers, and we report, to our knowledge, the first spindle cell lipoma in the thumb to help in the differential diagnosis of a similar swelling.

scholarly journals Histological and Ultrastructural Description of Benign Adipocytic Tumors in Farmed Striped Sea Bream (Lythognathus mormyrus)

Animals ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 3413
Author(s):  
Massimo Orioles ◽  
Marco Galeotti ◽  
Pierpaolo Patarnello ◽  
Stefano Pizzolitto ◽  
Donatella Volpatti
Keyword(s):  
Spindle Cell ◽  
Giant Cells ◽  
Collagen Fibers ◽  
Sea Bream ◽  
Spindle Cell Lipoma ◽  
Marine Aquaculture ◽  
Spindle Cells ◽  
Adipocytic Tumors ◽  
Abundant Cytoplasm ◽  
The Masses

Cutaneous neoplasms affecting wild striped bream (Lythognathus mormyrus) have been recorded after their introduction in a marine aquaculture farm in the Adriatic Sea. The tumors were evident on 24% of the reared fish, showing single or multiple nodules, with a diameter ranging between 0.5–4.0 cm. Histologically, all the neoplastic lesions were located in the stratum spongiosum of the dermis and were surrounded by a thin capsule of connective tissue. The tumors were predominantly composed of adipocytes grouped and surrounded by a thin net of fibroblasts and collagen fibers. In some lipomas a mixture of adipocytes and uniform spindle cells were also observed. Fibroblasts and collagen fibers, or spindle cells, showing few mitotic figures were mainly observed in other nodules. Three of the tumors showed bands of cells with elongated nuclei. Five neoplasms differed from the classic spindle cell lipoma due to the presence of scattered giant cells. These cells presented acidophilic abundant cytoplasm with multiple hyperchromatic nuclei showing a concentric “floret-like” arrangement. The tumors were further characterized by ultrastructural observations that allowed ruling out the presence of virus-like particles within the lesions. Histological features of the masses lead to the identification of four prevalent patterns of neoplasms: lipoma, fibrolipoma, spindle cell lipoma (SCL), and atypical spindle cell-like lipoma (ASCL). The different neoplasms could arise from the transformation of mesenchymal cells of dermal origin. To the author’s knowledge, this is the first report describing key differential histological and ultrastructural features of these neoplasms in striped sea bream.

scholarly journals Spindle Cell Lipoma of Scrotum

2019 ◽  
Vol 2 (2) ◽  
pp. e40-e41
Author(s):  
Muhammad Iqbal ◽  
Sanjay Agarwal ◽  
Iqbal S. Shergill
Keyword(s):  
Male Patient ◽  
Spindle Cell ◽  
Benign Lesion ◽  
Histopathological Diagnosis ◽  
Spindle Cell Lipoma ◽  
Rare Presentation ◽  
Left Half

Spindle cell lipoma (SCL) in the scrotum is a very rare presentation with only a few cases reported in the literature. The most common sites for this benign lesion are the neck, shoulder, and back. We present a 72-year-old male patient with painless swelling on the left half of the scrotum with a histopathological diagnosis of SCL.

scholarly journals A 37 mm Spindle Cell Lipoma on the Floor of the Mouth

2019 ◽  
Vol 2019 ◽  
pp. 1-4 ◽  
Author(s):  
Eve Malthiery ◽  
Valérie Costes-Martineau ◽  
Marie-Alix Fauroux ◽  
Jacques-Henri Torres
Keyword(s):  
Oral Cavity ◽  
Local Anesthesia ◽  
High Frequency ◽  
Spindle Cell ◽  
Spindle Cell Lipoma ◽  
Functional Consequence ◽  
Histological Features ◽  
Floor Of The Mouth ◽  
Spindle Cells ◽  
Male Patients

Spindle cell lipoma (SCL) is a rare variety of lipoma that mostly arises in male patients and rarely affects the oral cavity. The floor of the mouth is an uncommon site for SCL, and very few cases have been reported in this location. A case of SCL is reported in a 70-year-old woman who had noticed a swelling of the floor of the mouth without any functional consequence. Both ultrasonography and RMI suggested a diagnosis of ranula, whereas clinical palpation showed a nonfluctuant mass. The lesion was excised under local anesthesia. A 37×32 mm encapsulated yellow mass was removed. Histological features (mature adipocytes and CD34+ spindle cells) led to a diagnosis of SCL. Medical imaging assessment of this lesion could have been influenced by the high frequency of the ranulas in the floor of the mouth. This case appears to be quite infrequent because of its location (floor of the mouth), its size (over 3.5 cm), and the patient’s gender (female).

MIMICKING SOFT TISSUE TUMOUR- SPINDLE CELL LIPOMA

2021 ◽  
pp. 111-113
Author(s):  
Lahari Sampangi Ram Reddy ◽  
Indira Galidevara ◽  
Kannan R
Keyword(s):  
Spindle Cell ◽  
Complex Mixture ◽  
Variable Number ◽  
Soft Tissue Tumour ◽  
Spindle Cell Lipoma ◽  
Posterior Aspect ◽  
Spindle Cells ◽  
Tissue Tumour ◽  
The Right ◽  
Slow Growing

Spindle cell lipomas (SCL) are slow-growing benign adipocyte tumours that are most commonly seen in (1) the upper back, posterior aspect of the neck, and shoulders . Both genders are affected, but it is more (1) prevalent in males between the ages of 40 and 70 . Spindle cell lipoma is a benign tumour that is frequently confused with (1) liposarcoma. SCLs account for approximately 1.5 percent of all lipomatous tumours reported, making them uncommon . They (2) have a morphology similar to other benign and malignant fatty/spindle cell or myxoid lesions . Microscopically, it is a complex mixture of lipocytes and uniform spindle cells embedded in a mucinous matrix and traversed by (2) a variable number of birefringent collagen bres . Due to the unusual presentation and similar morphology of tumours, early diagnosis is critical; thus, diagnosis is based on clinical examination and conrmed by histopathological ndings. Because SCL has a favourable prognosis, wide local (1) excision is the treatment of choice . This is a case report of a 52-year-old male with a similar presentation in the right upper limb.

scholarly journals Spindle Cell Lipoma: A Case Report And Review Of Literature

2013 ◽  
Vol 10 (2) ◽  
pp. 92-95 ◽  
Author(s):  
P Chandrashekar ◽  
M Jose ◽  
M Dadhich ◽  
L Chatra ◽  
V Holla
Keyword(s):  
Medical Journal ◽  
Case Report ◽  
Spindle Cell ◽  
Histopathological Examination ◽  
English Literature ◽  
Review Of Literature ◽  
Spindle Cell Lipoma ◽  
Collagen Fibres ◽  
Spindle Cells ◽  
Rare Lesion

Oral spindle cell lipoma is a rare lesion and until now only 26 cases have been reported in English literature. In this article we report a case of oral spindle cell lipoma presented to our institution in July 2011, as an asymptomatic solitary growth of the buccal mucosa in a 58 year old male patient. On histopathological examination the lesion exhibited an admixture of adipocytes and spindle cells with collagen fibres and numerous mast cells. Kathmandu University Medical Journal | Vol.10 | No. 2 | Issue 38 | Apr – June 2012 | Page 92-95 DOI: http://dx.doi.org/10.3126/kumj.v10i2.7353

scholarly journals S-100 protein expressing spindle cells in spindle cell lipoma: a diagnostic pitfall

2016 ◽  
Vol 469 (4) ◽  
pp. 435-438 ◽  
Author(s):  
T. Mentzel ◽  
A. Rütten ◽  
M. Hantschke ◽  
J. L. Hornick ◽  
T. Brenn
Keyword(s):  
Spindle Cell ◽  
Spindle Cell Lipoma ◽  
Diagnostic Pitfall ◽  
Spindle Cells ◽  
S 100

Spindle Cell Lipoma of the Breast

1996 ◽  
Vol 37 (3P2) ◽  
pp. 893-895 ◽  
Author(s):  
D. N. Smith ◽  
C. M. Denison ◽  
S. C. Lester
Keyword(s):  
Spindle Cell ◽  
Spindle Cell Lipoma ◽  
Rare Type ◽  
Palpable Mass ◽  
Spindle Cells

A case of spindle cell lipoma of the breast found on mammography in a 53-year-old woman is presented. This rare type of tumor has been previously reported on only after its presentation as a palpable mass. Radiographically it appears as a well-circumscribed mass. Ultrasonographically it appears as a homogeneously hyperechoic nodule. Histologically these lesions are composed of spindle cells intermingled with adipocytes.

scholarly journals Intramuscular spindle cell lipoma/pleomorphic lipoma unusual site fore arm

2018 ◽  
Vol 6 (4) ◽  
pp. 1459
Author(s):  
Anu Anna Jacob ◽  
Geethanjali N. ◽  
Usha Poothiode
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Biopsy ◽  
Spindle Cell ◽  
Subcutaneous Tissue ◽  
Needle Aspiration ◽  
Spindle Cell Lipoma ◽  
Rare Presentation ◽  
Unusual Site ◽  
Fine Needle ◽  
Pleomorphic Lipoma

Pleomorphic lipoma/ spindle cell lipoma accounts for 15 % of lipoma within extremities, confining to the superficial plain comprising lower dermis and subcutaneous tissue. Intramuscular presentation in extrimities is a rare presentation. Here is a case of deep seated pleomorphic lipoma, of forearm, both on fine needle aspiration, biopsy and IHC confirmation. 100% of benign cases of lipoma are positive for CD 34, as stated in many studies and was also positive in our case.

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